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Atsushi Takahashi
Researcher at Tohoku University
Publications - 132
Citations - 9039
Atsushi Takahashi is an academic researcher from Tohoku University. The author has contributed to research in topics: Genome-wide association study & Catalysis. The author has an hindex of 40, co-authored 129 publications receiving 7490 citations. Previous affiliations of Atsushi Takahashi include National Institute of Advanced Industrial Science and Technology & Claude Bernard University Lyon 1.
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Journal ArticleDOI
Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations
Yukinori Okada,Michiaki Kubo,Hiroko Ohmiya,Atsushi Takahashi,Natsuhiko Kumasaka,Naoya Hosono,Shiro Maeda,Wanqing Wen,Rajkumar Dorajoo,Rajkumar Dorajoo,Min Jin Go,Wei Zheng,Norihiro Kato,Jer-Yuarn Wu,Jer-Yuarn Wu,Qi Lu,Tatsuhiko Tsunoda,Kazuhiko Yamamoto,Yusuke Nakamura,Naoyuki Kamatani,Toshihiro Tanaka +20 more
TL;DR: A genome-wide association study and replication studies with 62,245 east Asian subjects identified two new body mass index–associated loci and an interaction between a SNP in the KLF9 locus and one in the MSTN locus should provide useful insights into the etiology of obesity.
Journal ArticleDOI
Genetic variants in GPR126 are associated with adolescent idiopathic scoliosis.
Ikuyo Kou,Yohei Takahashi,Todd A. Johnson,Atsushi Takahashi,Long Guo,Jin Dai,Xu-sheng Qiu,Swarkar Sharma,Swarkar Sharma,Aki Takimoto,Yoji Ogura,Hua Jiang,Huang Yan,Katsuki Kono,Noriaki Kawakami,Koki Uno,Manabu Ito,Shohei Minami,Haruhisa Yanagida,Hiroshi Taneichi,Naoya Hosono,Taichi Tsuji,Teppei Suzuki,Hideki Sudo,Toshiaki Kotani,Ikuho Yonezawa,Douglas Londono,Derek Gordon,John A. Herring,John A. Herring,Kota Watanabe,Kazuhiro Chiba,Naoyuki Kamatani,Qing Jiang,Yuji Hiraki,Michiaki Kubo,Yoshiaki Toyama,Tatsuhiko Tsunoda,Carol Wise,Carol Wise,Yong Qiu,Chisa Shukunami,Morio Matsumoto,Shiro Ikegawa +43 more
TL;DR: A new susceptibility locus on chromosome 6q24.1 in Japanese is identified and the most significantly associated SNP, rs6570507, was in GPR126 (encoding G protein–coupled receptor 126), which was replicated in Han Chinese and European-ancestry populations.
Journal ArticleDOI
A genome-wide association study identifies an association of a common variant in TERT with susceptibility to idiopathic pulmonary fibrosis.
Taisei Mushiroda,Sukanya Wattanapokayakit,Atsushi Takahashi,Toshihiro Nukiwa,Shouji Kudoh,T. Ogura,H Taniguchi,Michiaki Kubo,Naoyuki Kamatani,Yusuke Nakamura +9 more
TL;DR: It is suggested that the common genetic variation within TERT may contribute to the risk of sporadic IFP in the Japanese population.
Journal ArticleDOI
Identification of type 2 diabetes loci in 433,540 East Asian individuals
Cassandra N. Spracklen,Cassandra N. Spracklen,Momoko Horikoshi,Young Jin Kim,Kuang Lin,Fiona Bragg,Sanghoon Moon,Ken Suzuki,Claudia H. T. Tam,Yasuharu Tabara,Soo Heon Kwak,Fumihiko Takeuchi,Jirong Long,Victor Jun Yu Lim,Jin-Fang Chai,Chien-Hsiun Chen,Masahiro Nakatochi,Jie Yao,Jie Yao,Hyeok Sun Choi,Apoorva K Iyengar,Hannah J Perrin,Sarah M Brotman,Martijn van de Bunt,Anna L. Gloyn,Jennifer E. Below,Jennifer E. Below,Michael Boehnke,Donald W. Bowden,John C. Chambers,Anubha Mahajan,Anubha Mahajan,Mark I. McCarthy,Maggie C.Y. Ng,Maggie C.Y. Ng,Lauren E. Petty,Lauren E. Petty,Weihua Zhang,Weihua Zhang,Andrew P. Morris,Andrew P. Morris,Andrew P. Morris,Linda S. Adair,Masato Akiyama,Zheng Bian,Juliana C.N. Chan,Li-Ching Chang,Miao-Li Chee,Yii-Der Ida Chen,Yii-Der Ida Chen,Yuan-Tsong Chen,Zhengming Chen,Lee-Ming Chuang,Shufa Du,Penny Gordon-Larsen,Myron D. Gross,Xiuqing Guo,Xiuqing Guo,Yu Guo,Sohee Han,Annie-Green Howard,Wei Huang,Yi-Jen Hung,Yi-Jen Hung,Mi Yeong Hwang,Chii-Min Hwu,Chii-Min Hwu,Sahoko Ichihara,Masato Isono,Hye-Mi Jang,Guozhi Jiang,Jost B. Jonas,Yoichiro Kamatani,Tomohiro Katsuya,Takahisa Kawaguchi,Chiea Chuen Khor,Chiea Chuen Khor,Katsuhiko Kohara,Myung-Shik Lee,Myung-Shik Lee,Nanette R. Lee,Liming Li,Jianjun Liu,Jianjun Liu,Andrea O.Y. Luk,Jun Lv,Yukinori Okada,Mark A Pereira,Charumathi Sabanayagam,Shi Jinxiu,Dong Mun Shin,Wing-Yee So,Atsushi Takahashi,Brian Tomlinson,Brian Tomlinson,Fuu Jen Tsai,Rob M. van Dam,Yong-Bing Xiang,Ken Yamamoto,Toshimasa Yamauchi,Kyungheon Yoon,Canqing Yu,Jian-Min Yuan,Liang Zhang,Wei Zheng,Michiya Igase,Yoon Shin Cho,Jerome I. Rotter,Jerome I. Rotter,Ya Xing Wang,Wayne Huey-Herng Sheu,Wayne Huey-Herng Sheu,Mitsuhiro Yokota,Jer-Yuarn Wu,Ching-Yu Cheng,Tien Yin Wong,Xiao-Ou Shu,Norihiro Kato,Kyong-Soo Park,Kyong-Soo Park,Kyong-Soo Park,E-Shyong Tai,Fumihiko Matsuda,Woon-Puay Koh,Ronald Cw Ma,Shiro Maeda,Iona Y Millwood,Ju Young Lee,Takashi Kadowaki,Robin G. Walters,Bong-Jo Kim,Karen L. Mohlke,Xueling Sim +132 more
TL;DR: A meta-analysis of genome-wide association study data from 77,418 individuals of East Asian ancestry with type 2 diabetes identifies novel variants associated with increased risk of type 2abetes in both East Asian and European populations.
Journal ArticleDOI
Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk
Ben Zhang,Wei Hua Jia,Koichi Matsuda,Sun-Seog Kweon,Keitaro Matsuo,Yong-Bing Xiang,Aesun Shin,Sun Ha Jee,Dong Hyun Kim,Qiuyin Cai,Jirong Long,Jiajun Shi,Wanqing Wen,Gong Yang,Yanfeng Zhang,Chun Li,Bingshan Li,Yan Guo,Zefang Ren,Bu Tian Ji,Zhi Zhong Pan,Atsushi Takahashi,Min-Ho Shin,Fumihiko Matsuda,Yu-Tang Gao,Jae Hwan Oh,Soriul Kim,Yoon Ok Ahn,Andrew T. Chan,Jenny Chang-Claude,Martha L. Slattery,Stephen B. Gruber,Fredrick R. Schumacher,Stephanie L. Stenzel,Graham Casey,Hyeong Rok Kim,Jin Young Jeong,Ji Won Park,Hong Lan Li,Satoyo Hosono,Sang-Hee Cho,Michiaki Kubo,Xiao-Ou Shu,Yi Xin Zeng,Wei Zheng +44 more
TL;DR: A genome-wide association study of CRC in East Asians with 14,963 cases and 31,945 controls and identified 6 new loci associated with CRC risk, which map to genes with established roles in colorectal tumorigenesis.