R
Raffaele Ferrari
Researcher at University College London
Publications - 46
Citations - 1923
Raffaele Ferrari is an academic researcher from University College London. The author has contributed to research in topics: Genome-wide association study & Frontotemporal dementia. The author has an hindex of 19, co-authored 46 publications receiving 1241 citations. Previous affiliations of Raffaele Ferrari include National Institutes of Health & Texas Tech University Health Sciences Center.
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Journal ArticleDOI
Genome, transcriptome and proteome: the rise of omics data and their integration in biomedical sciences.
Claudia Manzoni,Demis A. Kia,Jana Vandrovcova,John Hardy,Nicholas W. Wood,Patrick A. Lewis,Patrick A. Lewis,Raffaele Ferrari +7 more
TL;DR: This review cuts across the boundaries between genomics, transcriptomics and proteomics, summarizing how omics data are generated, analysed and shared and provides an overview of the current strengths and weaknesses of this global approach.
Journal ArticleDOI
Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies
Iris J. Broce,Celeste M. Karch,Natalie Wen,Chun Chieh Fan,Yunpeng Wang,Yunpeng Wang,Chin Hong Tan,Naomi Kouri,Owen A. Ross,Günter U. Höglinger,Günter U. Höglinger,Ulrich Müller,John Hardy,Parastoo Momeni,Christopher P. Hess,William P. Dillon,Zachary A. Miller,Luke W. Bonham,Gil D. Rabinovici,Howard J. Rosen,Gerard D. Schellenberg,Andre Franke,Tom H. Karlsen,Tom H. Karlsen,Jan H. Veldink,Raffaele Ferrari,Jennifer S. Yokoyama,Bruce L. Miller,Ole A. Andreassen,Ole A. Andreassen,Anders M. Dale,Rahul S. Desikan,Leo P. Sugrue +32 more
TL;DR: The genetic results suggest that for a subset of patients, immune dysfunction may contribute to FTD risk, and have potential implications for clinical trials targeting immune dysfunction in patients with FTD.
Journal ArticleDOI
Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture
Ruth Chia,Marya S. Sabir,Sara Bandres-Ciga,Sara Saez-Atienzar,Regina H. Reynolds,Regina H. Reynolds,Regina H. Reynolds,Emil K. Gustavsson,Emil K. Gustavsson,Ronald L. Walton,Samreen Ahmed,Coralie Viollet,Jinhui Ding,Mary B. Makarious,Monica Diez-Fairen,Makayla K. Portley,Zalak Shah,Yevgeniya Abramzon,Yevgeniya Abramzon,Dena G. Hernandez,Cornelis Blauwendraat,David J. Stone,John D. Eicher,Laura Parkkinen,Olaf Ansorge,Lorraine N. Clark,Lawrence S. Honig,Karen Marder,Afina W. Lemstra,Peter St George-Hyslop,Peter St George-Hyslop,Elisabet Londos,Kevin Morgan,Tammaryn Lashley,Thomas T. Warner,Zane Jaunmuktane,Douglas Galasko,Isabel Santana,Pentti J. Tienari,Liisa Myllykangas,Minna Oinas,Nigel J. Cairns,John C. Morris,Glenda M. Halliday,Vivianna M. Van Deerlin,John Q. Trojanowski,Maurizio Grassano,Maurizio Grassano,Andrea Calvo,Gabriele Mora,Antonio Canosa,Gianluca Floris,Ryan C. Bohannan,Francesca Brett,Ziv Gan-Or,Joshua T. Geiger,Anni Moore,Patrick May,Rejko Krüger,Rejko Krüger,David S. Goldstein,Grisel Lopez,Nahid Tayebi,Ellen Sidransky,Lucy Norcliffe-Kaufmann,Jose-Alberto Palma,Horacio Kaufmann,Vikram G. Shakkottai,Matthew H. Perkins,Kathy L. Newell,Thomas Gasser,Claudia Schulte,Francesco Landi,Erika Salvi,Daniele Cusi,Eliezer Masliah,Ronald C. Kim,Chad A. Caraway,Edwin S. Monuki,Maura Brunetti,Ted M. Dawson,Liana S. Rosenthal,Marilyn S. Albert,Olga Pletnikova,Juan C. Troncoso,Margaret E. Flanagan,Qinwen Mao,Eileen H. Bigio,Eloy Rodríguez-Rodríguez,Jon Infante,Carmen Lage,Isabel González-Aramburu,Pascual Sánchez-Juan,Bernardino Ghetti,Julia Keith,Sandra E. Black,Mario Masellis,Ekaterina Rogaeva,Charles Duyckaerts,Alexis Brice,Suzanne Lesage,Georgia Xiromerisiou,Matthew J. Barrett,Bension S. Tilley,Steve M. Gentleman,Giancarlo Logroscino,Geidy E. Serrano,Thomas G. Beach,Ian G. McKeith,Alan J. Thomas,Johannes Attems,Christopher Morris,Laura Palmer,Seth Love,Claire Troakes,Safa Al-Sarraj,Angela Hodges,Dag Aarsland,Dag Aarsland,Gregory Klein,Scott M. Kaiser,Randy Woltjer,Pau Pastor,Lynn M. Bekris,James B. Leverenz,Lilah M. Besser,Amanda B. Kuzma,Alan E. Renton,Alison Goate,David A. Bennett,Clemens R. Scherzer,Huw R. Morris,Raffaele Ferrari,Diego Albani,Stuart Pickering-Brown,Kelley Faber,Walter A. Kukull,Estrella Morenas-Rodríguez,Estrella Morenas-Rodríguez,Alberto Lleó,Juan Fortea,Daniel Alcolea,Jordi Clarimón,Mike A. Nalls,Luigi Ferrucci,Susan M. Resnick,Toshiko Tanaka,Tatiana Foroud,Neill R. Graff-Radford,Zbigniew K. Wszolek,Tanis J. Ferman,Bradley F. Boeve,John Hardy,Eric J. Topol,Ali Torkamani,Andrew B. Singleton,Mina Ryten,Mina Ryten,Dennis W. Dickson,Adriano Chiò,Owen A. Ross,J. Raphael Gibbs,Clifton L. Dalgard,Bryan J. Traynor,Bryan J. Traynor,Bryan J. Traynor,Sonja W. Scholz +166 more
TL;DR: This article performed whole-genome sequencing in large cohorts of Lewy body dementia (LBD) cases and neurologically healthy controls to study the genetic architecture of this understudied form of dementia, and to generate a resource for the scientific community.
Journal ArticleDOI
NeuroChip, an updated version of the NeuroX genotyping platform to rapidly screen for variants associated with neurological diseases
Cornelis Blauwendraat,Faraz Faghri,Lasse Pihlstrøm,Joshua T. Geiger,Alexis Elbaz,Suzanne Lesage,Jean-Christophe Corvol,Patrick May,Aude Nicolas,Yevgeniya Abramzon,Natalie A. Murphy,J. Raphael Gibbs,Mina Ryten,Raffaele Ferrari,Jose Bras,Rita Guerreiro,Julie Williams,Rebecca Sims,Steven J. Lubbe,Dena G. Hernandez,Kin Y. Mok,Kin Y. Mok,Laurie Robak,Roy H. Campbell,Ekaterina Rogaeva,Bryan J. Traynor,Ruth Chia,Sun Ju Chung,John Hardy,Alexis Brice,Nicholas W. Wood,Henry Houlden,Joshua M. Shulman,Huw R. Morris,Thomas Gasser,Thomas Gasser,Rejko Krüger,Peter Heutink,Peter Heutink,Manu Sharma,Javier Simón-Sánchez,Javier Simón-Sánchez,Mike A. Nalls,Andrew B. Singleton,Sonja W. Scholz +44 more
TL;DR: The NeuroChip has a more comprehensive and improved content, which makes it a reliable, high-throughput, cost-effective screening tool for genetic research and molecular diagnostics in neurodegenerative diseases.
Journal ArticleDOI
Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study
Cyril Pottier,Xiaolai Zhou,Ralph B. Perkerson,Matthew B. Baker,Gregory D. Jenkins,Daniel J. Serie,Roberta Ghidoni,Luisa Benussi,Giuliano Binetti,Adolfo López de Munain,Adolfo López de Munain,Miren Zulaica,Miren Zulaica,Fermin Moreno,Fermin Moreno,Isabelle Le Ber,Florence Pasquier,Didier Hannequin,Raquel Sánchez-Valle,Anna Antonell,Albert Lladó,Tammee M. Parsons,Nicole A. Finch,Elizabeth Finger,Carol F. Lippa,Edward D. Huey,Manuela Neumann,Manuela Neumann,Peter Heutink,Peter Heutink,Matthis Synofzik,Matthis Synofzik,Carlo Wilke,Carlo Wilke,Robert A. Rissman,Robert A. Rissman,Jarosław Sławek,Emilia J. Sitek,Peter Johannsen,Jorgen E. Nielsen,Yingxue Ren,Marka van Blitterswijk,Mariely DeJesus-Hernandez,Elizabeth Christopher,Melissa E. Murray,Kevin F. Bieniek,Bret M. Evers,Camilla Ferrari,Sara Rollinson,Anna Richardson,Elio Scarpini,Giorgio G. Fumagalli,Giorgio G. Fumagalli,Alessandro Padovani,John Hardy,Parastoo Momeni,Raffaele Ferrari,Francesca Frangipane,Raffaele Maletta,Maria Anfossi,Maura Gallo,Leonard Petrucelli,EunRan Suh,Oscar L. Lopez,Tsz H. Wong,Jeroen van Rooij,Harro Seelaar,Simon Mead,Richard J. Caselli,Eric M. Reiman,Marwan N. Sabbagh,Mads Kjolby,Anders Nykjaer,Anna Karydas,Adam L. Boxer,Lea T. Grinberg,Jordan Grafman,Salvatore Spina,Salvatore Spina,Adrian L. Oblak,M.-Marsel Mesulam,Sandra Weintraub,Changiz Geula,John R. Hodges,Olivier Piguet,William S. Brooks,William S. Brooks,David J. Irwin,John Q. Trojanowski,Edward B. Lee,Keith A. Josephs,Joseph E. Parisi,Nilufer Ertekin-Taner,David S. Knopman,Benedetta Nacmias,Irene Piaceri,Silvia Bagnoli,Sandro Sorbi,Marla Gearing,Jonathan Glass,Thomas G. Beach,Sandra E. Black,Mario Masellis,Ekaterina Rogaeva,Jean-Paul Vonsattel,Lawrence S. Honig,Julia Kofler,Amalia C. Bruni,Julie S. Snowden,David M. A. Mann,Stuart Pickering-Brown,Janine Diehl-Schmid,Juliane Winkelmann,Daniela Galimberti,Caroline Graff,Linn Öijerstedt,Claire Troakes,Safa Al-Sarraj,Safa Al-Sarraj,Carlos Cruchaga,Nigel J. Cairns,Jonathan D. Rohrer,Glenda M. Halliday,John B.J. Kwok,John C. van Swieten,John C. van Swieten,Charles L. White,Bernardino Ghetti,Jill R. Murell,Ian R. Mackenzie,Ging-Yuek Robin Hsiung,Barbara Borroni,Giacomina Rossi,Fabrizio Tagliavini,Zbigniew K. Wszolek,Ronald C. Petersen,Eileen H. Bigio,Murray Grossman,Vivianna M. Van Deerlin,William W. Seeley,Bruce L. Miller,Neill R. Graff-Radford,Bradley F. Boeve,Dennis W. Dickson,Joanna M. Biernacka,Rosa Rademakers +145 more
TL;DR: In this paper, a meta-analysis was conducted to identify potential genetic modifiers of disease onset and disease risk in frontotemporal lobar degeneration (FTLD) carriers.