Linn Öijerstedt

TL;DR: In this paper, a meta-analysis was conducted to identify potential genetic modifiers of disease onset and disease risk in frontotemporal lobar degeneration (FTLD) carriers.

TL;DR: It is proposed that maintaining the efficient organization of the brain's functional network supports cognitive health even as atrophy and connectivity decline presymptomatically.

TL;DR: In this paper, facial emotion recognition (FER) and faux pas (FP) recognition tests were used to study social cognition within the Genetic Frontotemporal Dementia Initiative (GENFI), a large familial FTD cohort of C9orf72, GRN, and MAPT mutation carriers.

TL;DR: Data is presented here on the incidence of trisomy 21 mosaicism in a cohort of normal fetal ovarian samples, indicating that an accumulation of tr isomy 21 germ cells does indeed take place during fetal oogenesis, and this trend continues during the third trimester of pregnancy and postnatally, up until ovulation, thereby explaining the maternal age effect in Down syndrome.

TL;DR: In this paper, a multiplexed antibody-based suspension bead array was used to analyse levels of 111 proteins in CSF samples from 221 individuals from families with genetic frontotemporal dementia.