C
Christopher J. O'Donnell
Researcher at VA Boston Healthcare System
Publications - 914
Citations - 140860
Christopher J. O'Donnell is an academic researcher from VA Boston Healthcare System. The author has contributed to research in topics: Framingham Heart Study & Genome-wide association study. The author has an hindex of 159, co-authored 869 publications receiving 126278 citations. Previous affiliations of Christopher J. O'Donnell include Brown University & Veterans Health Administration.
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Mendelian Randomization evaluation of causal effects of fibrinogen on incident coronary heart disease
Cavin K. Ward-Caviness,Paul S. de Vries,Paul S. de Vries,Kerri L. Wiggins,Jennifer E. Huffman,Lisa R. Yanek,Lawrence F. Bielak,Franco Giulianini,Xiuqing Guo,Marcus E. Kleber,Marcus E. Kleber,Tim Kacprowski,Stefan Groβ,Astrid Petersman,George Davey Smith,Fernando Pires Hartwig,Fernando Pires Hartwig,Jack Bowden,Gibran Hemani,Martina Muller-Nuraysid,Konstantin Strauch,Wolfgang Koenig,Wolfgang Koenig,Melanie Waldenberger,Thomas Meitinger,Nathan Pankratz,Eric Boerwinkle,Eric Boerwinkle,Weihong Tang,Yi-Ping Fu,Andrew D. Johnson,Ci Song,Moniek P.M. de Maat,André G. Uitterlinden,Oscar H. Franco,Jennifer A. Brody,Barbara McKnight,Yii-Der Ida Chen,Bruce M. Psaty,Rasika A. Mathias,Diane M. Becker,Patricia A. Peyser,Jennifer A. Smith,Suzette J. Bielinski,Paul M. Ridker,Kent D. Taylor,Jie Yao,Russell P. Tracy,Graciela E. Delgado,Stella Trompet,Stella Trompet,Naveed Sattar,J. Wouter Jukema,Lewis C. Becker,Sharon L.R. Kardia,Jerome I. Rotter,Winfried März,Winfried März,Winfried März,Marcus Dörr,Daniel I. Chasman,Abbas Dehghan,Abbas Dehghan,Christopher J. O'Donnell,Nicholas L. Smith,Nicholas L. Smith,Nicholas L. Smith,Annette Peters,Alanna C. Morrison +68 more
TL;DR: An important update to initial Mendelian Randomization analyses of the causal effect of fibrinogen on coronary heart disease (CHD) utilized single variants and did not take advantage of modern, multivariant approaches is provided.
Journal ArticleDOI
Abstract 12228: Development of a Novel Polygenic Risk Score to Predict Risk of Aortic Stenosis Events
Aeron Small,Giorgio E. M. Melloni,Frederick K. Kamanu,Carolina Roselli,Brian A. Bergmark,Marc P. Bonaca,Michelle ODonoghue,Robert P. Giugliano,Benjamin M. Scirica,Deepak L. Bhatt,Elliott M. Antman,Itamar Raz,Gina M. Peloso,Peter W.F. Wilson,Christopher J. O'Donnell,Pradeep Natarajan,Eugene Braunwald,Steven A. Lubitz,Patrick T. Ellinor,Christian T. Ruff,Marc S. Sabatine +20 more
TL;DR: The authors developed a novel polygenic risk score that predicts clinical risk of aortic stenosis-related adverse events in patients with cardiometabolic disease, even after adjustment for traditional risk factors.
Journal ArticleDOI
Prevalence and distribution of aortic plaque by sex and age group among community-dwelling adults.
Saadia Qazi,Philimon Gona,Noriko Oyama-Manabe,Carol J Salton,Christopher J. O'Donnell,Warren J. Manning,Michael L Chuang +6 more
TL;DR: In this article , non-calcified atherosclerotic plaque in the descending aorta was quantified by noncontrast cardiovascular magnetic resonance (CMR) in a community-dwelling cohort of adults.
Posted ContentDOI
Estimating State-Allocable Production Technologies When There are Two States of Nature and State Allocations of Inputs are Unobserved
TL;DR: In this paper, a Bayesian methodology is used to estimate more flexible types of state-contingent technologies, including the theory of the firm, principal-agent relationships, and consumer choice.