scispace - formally typeset
C

Christopher J. O'Donnell

Researcher at VA Boston Healthcare System

Publications -  914
Citations -  140860

Christopher J. O'Donnell is an academic researcher from VA Boston Healthcare System. The author has contributed to research in topics: Framingham Heart Study & Genome-wide association study. The author has an hindex of 159, co-authored 869 publications receiving 126278 citations. Previous affiliations of Christopher J. O'Donnell include Brown University & Veterans Health Administration.

Papers
More filters
Journal ArticleDOI

γ′ Fibrinogen: Evaluation of a New Assay for Study of Associations with Cardiovascular Disease

Rehana S. Lovely, +6 more
- 01 May 2010 - 
TL;DR: An immunometric technique to measure gamma' fibrinogen concentrations in plasma shows excellent utility for cardiovascular risk analysis and the sensitivity and specificity of gamma’ fibr inogen in evaluating CAD patients was determined with ROC curve analysis.
Journal ArticleDOI

Parental Obesity and Offspring Serum Alanine and Aspartate Aminotransferase Levels: The Framingham Heart Study

Rohit Loomba, +12 more
- 01 Apr 2008 - 
TL;DR: Early-onset paternal obesity, but not maternal obesity, increases the odds of elevated serum ALT levels in offspring, suggesting a predisposition to developing elevated serum alanine aminotransferase levels that may be mediated through familial early-ONSet obesity.
Journal ArticleDOI

Assessment by cardiovascular magnetic resonance, electron beam computed tomography, and carotid ultrasonography of the distribution of subclinical atherosclerosis across Framingham risk strata.

Sekar Kathiresan, +12 more
- 01 Feb 2007 - 
TL;DR: In a community-based sample, correlations among subclinical Atherosclerosis test results are low, and a substantial proportion has high levels of subclinical atherosclerosis detected on >or=2 imaging tests.
Journal ArticleDOI

Evidence for a Gene Influencing Serum Bilirubin on Chromosome 2q Telomere: A Genomewide Scan in the Framingham Study

Jing-Ping Lin, +5 more
- 01 Apr 2003 - 
TL;DR: The genome scan demonstrated significant evidence of linkage of serum bilirubin to chromosome 2q, with a LOD score of 3.8 at location 243 cM, and it is suggested that UGT1A1 may be a major gene controlling serum bilIRubin levels in the population.
Journal ArticleDOI

Assessment of Genetic Determinants of the Association of γ′ Fibrinogen in Relation to Cardiovascular Disease

Rehana S. Lovely, +8 more
- 01 Oct 2011 - 
TL;DR: A genome-wide association study on 3042 participants from the Framingham Heart Study Offspring Cohort found fibrinogen is associated with prevalent CVD and with SNPs exclusively in and near the fibrInogen gene locus, which encodes the &ggr; chain.