C
Christopher J. O'Donnell
Researcher at VA Boston Healthcare System
Publications - 914
Citations - 140860
Christopher J. O'Donnell is an academic researcher from VA Boston Healthcare System. The author has contributed to research in topics: Framingham Heart Study & Genome-wide association study. The author has an hindex of 159, co-authored 869 publications receiving 126278 citations. Previous affiliations of Christopher J. O'Donnell include Brown University & Veterans Health Administration.
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High-throughput Multimodal Automated Phenotyping (MAP) with Application to PheWAS
Katherine P. Liao,Katherine P. Liao,Katherine P. Liao,Jiehuan Sun,Jiehuan Sun,Tianrun Cai,Tianrun Cai,Tianrun Cai,Nicholas Link,Chuan Hong,Jie Huang,Jennifer E. Huffman,Jessica L. Gronsbell,Yichi Zhang,Yichi Zhang,Yuk Lam Ho,Victor M. Castro,Vivian S. Gainer,Shawn N. Murphy,Christopher J. O'Donnell,Christopher J. O'Donnell,J. Michael Gaziano,J. Michael Gaziano,J. Michael Gaziano,Kelly Cho,Kelly Cho,Kelly Cho,Peter Szolovits,Isaac S. Kohane,Sheng Yu,Tianxi Cai,Tianxi Cai +31 more
TL;DR: An automated high-throughput phenotyping method integrating International Classification of Diseases codes and narrative data extracted using natural language processing (NLP) is developed, facilitating use in studies requiring large scale phenotypes, such as PheWAS.
Journal ArticleDOI
Mendelian Randomization Evidence for Cardiovascular Precision Medicine.
Journal ArticleDOI
Predictive densities for models with stochastic regressors and inequality constraints: Forecasting local-area wheat yield
TL;DR: In this paper, the authors describe and illustrate how to obtain forecasts when some of those regressors are stochastic and their values have not yet been realized, using a Bayesian predictive density.
Journal ArticleDOI
Cross-Ancestry Investigation of Venous Thromboembolism Genomic Predictors
Florian Thibord,Derek Klarin,Jennifer A. Brody,Ming-Huei Chen,Michael Levin,Daniel I. Chasman,Ellen L. Goode,Kristian Hveem,Maris Teder-Laving,Angel Martinez-Perez,Dylan Aïssi,Delphine Daian-Bacq,Kaoru Ito,Pradeep Natarajan,Pamela L. Lutsey,Girish N. Nadkarni,Paul S. de Vries,Gabriel Cuellar-Partida,Brooke N. Wolford,Jack Pattee,Charles Kooperberg,S. Braekkan,Ruifang Li-Gao,Noémie Saut,Corriene Sept,Marine Germain,Renae Judy,Kerri L. Wiggins,Darae Ko,Christopher J. O'Donnell,Kent D. Taylor,Franco Giulianini,Mariza de Andrade,Therese Haugdahl Nøst,Anne Boland,Jean-Philippe Empana,Satoshi Koyama,Thomas Gilliland,Ron Do,Jennifer E. Huffman,Xin Wang,Wei Zhou,José Manuel Soria,Juan Carlos Souto,Nathan Pankratz,Jeffrey Haessler,Kristian Hindberg,Frits R. Rosendaal,Constance Turman,Robert Olaso,Rachel L. Kember,Traci M. Bartz,Julie Lynch,Susan R. Heckbert,Sebastian M. Armasu,Ben Michael Brumpton,David M. Smadja,Xavier Jouven,Issei Komuro,Katharine R. Clapham,Ruth J. F. Loos,Cristen J. Willer,Maria Sabater-Lleal,James S. Pankow,Alexander P. Reiner,Vânia M. Morelli,Paul M. Ridker,Astrid van Hylckama Vlieg,Jean-François Deleuze,Peter Kraft,Daniel J. Rader,Kyung Min Lee,Bruce M. Psaty,Anne Heidi Skogholt,Joseph Emmerich,Pierre Suchon,Stephen S. Rich,Ha My T. Vy,Weihong Tang,Rebecca D. Jackson,J. D. Hansen,Pierre-Emmanuel Morange,Christopher Kabrhel,David-Alexandre Trégouët,Scott M. Damrauer,Andrew Johnson,Nicholas L. Smith +86 more
TL;DR: The authors' cross-ancestry GWAS meta-analyses identified new loci associated with VTE, which highlight new pathways to thrombosis and provide novel molecules that may be useful in the development of improved antithrombotic treatments.
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Current practice and future promise for clinical noninvasive measurements of subclinical atherosclerotic disease in the elderly.
TL;DR: Ongoing studies will provide important information regarding the appropriate role of the many newer, high-resolution tests of subclinical atherosclerosis in disease prediction, treatment, and tracking of disease progression in the elderly.