C
Christopher J. O'Donnell
Researcher at VA Boston Healthcare System
Publications - 914
Citations - 140860
Christopher J. O'Donnell is an academic researcher from VA Boston Healthcare System. The author has contributed to research in topics: Framingham Heart Study & Genome-wide association study. The author has an hindex of 159, co-authored 869 publications receiving 126278 citations. Previous affiliations of Christopher J. O'Donnell include Brown University & Veterans Health Administration.
Papers
More filters
Posted ContentDOI
Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes
Julia K. Goodrich,Moriel Singer-Berk,Rachel Son,Abigail Sveden,Jordan Wood,Eleina M. England,Joanne B. Cole,Ben Weisburd,Nicholas A. Watts,Zachary Zappala,Haichen Zhang,Kristin A. Maloney,Andrew Dahl,Carlos A. Aguilar-Salinas,Gil Atzmon,Gil Atzmon,Francisco Barajas-Olmos,Nir Barzilai,John Blangero,Eric Boerwinkle,Eric Boerwinkle,Lori L. Bonnycastle,Erwin P. Bottinger,Donald W. Bowden,Federico Centeno-Cruz,John C. Chambers,John C. Chambers,Nathalie Chami,Nathalie Chami,Edmund Chan,Juliana C.N. Chan,Ching-Yu Cheng,Yoon Shin Cho,Cecilia Contreras-Cubas,Emilio J. Cordova,Adolfo Correa,Ralph A. DeFronzo,Ravindranath Duggirala,Josée Dupuis,Ma. Eugenia Garay-Sevilla,Humberto García-Ortiz,Christian Gieger,Benjamin Glaser,Clicerio González-Villalpando,Ma Elena Gonzalez,Niels Grarup,Leif Groop,Leif Groop,Myron D. Gross,Christopher A. Haiman,Sohee Han,Craig L. Hanis,Torben Hansen,Nancy L. Heard-Costa,Brian E. Henderson,Juan Manuel Malacara Hernandez,Mi Yeong Hwang,Sergio Islas-Andrade,Marit E. Jørgensen,Marit E. Jørgensen,Marit E. Jørgensen,Hyun Min Kang,Bong-Jo Kim,Young-Jin Kim,Heikki A. Koistinen,Heikki A. Koistinen,Heikki A. Koistinen,Jaspal S. Kooner,Johanna Kuusisto,Soo Heon Kwak,Markku Laakso,Leslie A. Lange,Jong-Young Lee,Juyoung Lee,Donna M. Lehman,Allan Linneberg,Allan Linneberg,Jianjun Liu,Jianjun Liu,Ruth J. F. Loos,Ruth J. F. Loos,Valeriya Lyssenko,Valeriya Lyssenko,Ronald C.W. Ma,Angélica Martínez-Hernández,James B. Meigs,James B. Meigs,Thomas Meitinger,Elvia Mendoza-Caamal,Karen L. Mohlke,Andrew D. Morris,Andrew D. Morris,Alanna C. Morrison,Maggie C.Y. Ng,Peter M. Nilsson,Christopher J. O'Donnell,Lorena Orozco,Colin N. A. Palmer,Kyong Soo Park,Kyong Soo Park,Kyong Soo Park,Wendy S. Post,Oluf Pedersen,Michael Preuss,Bruce M. Psaty,Bruce M. Psaty,Alexander P. Reiner,Cristina Revilla-Monsalve,Stephen S. Rich,Jerome I. Rotter,Danish Saleheen,Claudia Schurmann,Claudia Schurmann,Xueling Sim,Robert Sladek,Kerrin S. Small,Wing-Yee So,Xavier Soberón,Tim D. Spector,Konstantin Strauch,Tim M. Strom,E. Shyong Tai,Claudia H. T. Tam,Yik Ying Teo,Farook Thameem,Brian Tomlinson,Russell P. Tracy,Tiinamaija Tuomi,Jaakko Tuomilehto,Teresa Tusié-Luna,Rob M. van Dam,Rob M. van Dam,Ramachandran S. Vasan,James G. Wilson,Daniel R. Witte,Tien Yin Wong,Lizz Caulkins,Noël P. Burtt,Noah Zaitlen,Mark I. McCarthy,Mark I. McCarthy,Michael Boehnke,Toni I. Pollin,Jason Flannick,Jason Flannick,Jason Flannick,Josep M. Mercader,Josep M. Mercader,Anne H. O’Donnell-Luria,Anne H. O’Donnell-Luria,Anne H. O’Donnell-Luria,Samantha Baxter,Jose C. Florez,Jose C. Florez,Daniel G. MacArthur,Daniel G. MacArthur,Miriam S. Udler-Aubrey,Miriam S. Udler-Aubrey,for Amp-T D-Genes Consortia +158 more
TL;DR: Additional epidemiologic and genetic factors contributing to risk prediction are assessed, demonstrating that inclusion of common polygenic variation significantly improved biomarker estimation for two monogenic dyslipidemias.
Journal ArticleDOI
A Response to “Holding GUSTO Up to the Light”
TL;DR: The GustO investigators dispute the statement that no thrombolytic regimen in the GUSTO trial showed any mortality advantage for patients treated 4 or more hours after symptom onset, a critical issue because most patients with acute myocardial infarction in the United States come to the hospital during this time frame.
Journal ArticleDOI
Aging syndrome genes and premature coronary artery disease
Adrian F. Low,Christopher J. O'Donnell,Christopher J. O'Donnell,Sekar Kathiresan,Sekar Kathiresan,Brendan M. Everett,Claudia U. Chae,Stanley Y. Shaw,Patrick T. Ellinor,Calum A. MacRae +9 more
TL;DR: The data do not support the hypothesis that premature CAD is associated with common variants in the progeroid syndrome genes LMNA and KLOTHO.
Journal ArticleDOI
A systematic heritability analysis of the human whole blood transcriptome.
Tianxiao Huan,Chunyu Liu,Roby Joehanes,Xiaoling Zhang,Brian H. Chen,Andrew D. Johnson,Chen Yao,Paul Courchesne,Christopher J. O'Donnell,Peter J. Munson,Daniel Levy +10 more
TL;DR: It is discovered that BMI GWAS SNPs in 16p11.2 are associated with several BMI differentially expressed genes in a cis manner (e.g., SULT1A1, SPNS1, and TUFM).
Journal ArticleDOI
Weed seed spread and its prevention: The role of roadside wash down.
Ali Ahsan Bajwa,Thi Minh Hong Nguyen,Thi Minh Hong Nguyen,S. C. Navie,Christopher J. O'Donnell,Steve W. Adkins +5 more
TL;DR: The roadside wash down facilities found throughout Queensland can remove a substantial amount of viable weed seed from vehicles, including the invasive parthenium weed, and the use of such facilities should be strongly encouraged.