C
Christopher J. O'Donnell
Researcher at VA Boston Healthcare System
Publications - 914
Citations - 140860
Christopher J. O'Donnell is an academic researcher from VA Boston Healthcare System. The author has contributed to research in topics: Framingham Heart Study & Genome-wide association study. The author has an hindex of 159, co-authored 869 publications receiving 126278 citations. Previous affiliations of Christopher J. O'Donnell include Brown University & Veterans Health Administration.
Papers
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Journal ArticleDOI
A MUC5B Gene Polymorphism, rs35705950-T, Confers Protective Effects Against COVID-19 Hospitalization but Not Severe Disease or Mortality
Anurag Verma,Jessica Minnier,Emily S. Wan,Jennifer E. Huffman,Lina Gao,Jacob Joseph,Yuk-Lam Ho,Wen-Chih Wu,Kelly Cho,Bryan L. Gorman,Nallakkandi Rajeevan,Saiju Pyarajan,Helene Garcon,James B. Meigs,Yan V. Sun,Peter D. Reaven,John E. McGeary,A. Suzuki,Joel Gelernter,Julie Lynch,Jeffrey M Peterson,Seyedeh M. Zekavat,Pradeep Natarajan,Sharvari Dalal,Darshana Jhala,Mehrdad Arjomandi,Elise Gatsby,Kristine E. Lynch,Robert A. Bonomo,Mathew S. Freiberg,Gita A. Pathak,Jin Zhou,Curtis J. Donskey,R. Madduri,Quinn S. Wells,Rose D L Huang,Renato Polimanti,Kyong-Mi Chang,Katherine P. Liao,Philip S. Tsao,Peter W.F. Wilson,Adriana M. Hung,Christopher J. O'Donnell,John Michael Gaziano,Richard L. Hauger,Sudha K. Iyengar,Shiuh Wen Luoh +46 more
TL;DR: The MUC5B variant rs35705950-T may confer protection in COVID-19 hospitalizations and among MVP individuals of European ancestry, it was associated with fewer post-CO VID-19 pneumonia events.
Posted Content
Imposing Observation-Varying Equality Constraints Using Generalised Restricted Least Squares
TL;DR: In this paper, a generalized restricted least squares (GRLS) estimator is proposed for estimating a constant returns to scale production function, which collapses to RLS in cases where the restrictions are observation-invariant.
Journal Article
The combined effect of biological control with plant competition on the management of parthenium weed (parthenium hysterophorus l.)
Asad Shabbir,Kunjithapatham Dhileepan,Myron P. Zalucki,Christopher J. O'Donnell,Naeem Khan,Zahid Hanif,Steve W. Adkins +6 more
TL;DR: Biological control and competitive plants can complement one another to bring about improved management of parthenium weed in Australia and this approach may be adopted in countries where some of the biological control agents are already present.
Journal ArticleDOI
Genetic loci associated with prevalent and incident myocardial infarction and coronary heart disease in the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium
Julie Hahn,Yi-Ping Fu,Michael R. Brown,Joshua C. Bis,Paul S. de Vries,Paul S. de Vries,Mary F. Feitosa,Lisa R. Yanek,Stefan Weiss,Franco Giulianini,Albert V. Smith,Xiuqing Guo,Traci M. Bartz,Diane M. Becker,Lewis C. Becker,Eric Boerwinkle,Eric Boerwinkle,Jennifer A. Brody,Yii-Der Ida Chen,Oscar H. Franco,Megan L. Grove,Tamara B. Harris,Albert Hofman,Albert Hofman,Shih-Jen Hwang,Brian G. Kral,Lenore J. Launer,Marcello Ricardo Paulista Markus,Kenneth Rice,Stephen S. Rich,Paul M. Ridker,Paul M. Ridker,Fernando Rivadeneira,Jerome I. Rotter,Nona Sotoodehnia,Kent D. Taylor,André G. Uitterlinden,André G. Uitterlinden,Uwe Völker,Henry Völzke,Jie Yao,Daniel I. Chasman,Daniel I. Chasman,Marcus Dörr,Vilmundur Gudnason,Rasika A. Mathias,Wendy S. Post,Bruce M. Psaty,Abbas Dehghan,Abbas Dehghan,Christopher J. O'Donnell,Alanna C. Morrison +51 more
TL;DR: One known locus (ANGPTL4), four new loci (PLCL1, RC3H2, TMPRSS5, and LDLRAD1) associated with cardiovascular disease risk that warrant further investigation, and no loci were significantly associated with all-cause mortality following a MI or CHD event.