C
Christopher J. O'Donnell
Researcher at VA Boston Healthcare System
Publications - 914
Citations - 140860
Christopher J. O'Donnell is an academic researcher from VA Boston Healthcare System. The author has contributed to research in topics: Framingham Heart Study & Genome-wide association study. The author has an hindex of 159, co-authored 869 publications receiving 126278 citations. Previous affiliations of Christopher J. O'Donnell include Brown University & Veterans Health Administration.
Papers
More filters
Journal ArticleDOI
Integrative DNA, RNA, and Protein Evidence Connects TREML4 to Coronary Artery Calcification
Shurjo K. Sen,Kimberly Boelte,Jennifer J. Barb,Roby Joehanes,Xiaoqing Zhao,Qi Cheng,Lila Adams,Jamie K. Teer,David S. Accame,Soma Chowdhury,Larry N. Singh,Maryam Kavousi,Patricia A. Peyser,Laura Quigley,Debra A. Long Priel,Karen Lau,Douglas B. Kuhns,Teizo Yoshimura,Andrew D. Johnson,Shih-Jen Hwang,Marcus Y. Chen,Andrew E. Arai,Eric D. Green,James C. Mullikin,Frank D. Kolodgie,Christopher J. O'Donnell,Renu Virmani,Peter J. Munson,Daniel W. McVicar,Leslie G. Biesecker +29 more
TL;DR: Overall, integrative RNA, DNA, and protein evidence implicating TREML4 in coronary artery calcification is presented, which connects multimodal genomics data with a commonly used clinical marker of cardiovascular disease.
Journal Article
Common variants at 10 genomic loci influence hemoglobin A1C levels via glycemic and nonglycemic pathways (Diabetes (2010) 59, (3229-3239))
Nicole Soranzo,Serena Sanna,Eleanor Wheeler,Christian Gieger,Dörte Radke,Josée Dupuis,Nabila Bouatia-Naji,Claudia Langenberg,Inga Prokopenko,Elliot S. Stolerman,Manjinder S. Sandhu,Matthew M. Heeney,Joseph M. Devaney,Muredach P. Reilly,Sally L. Ricketts,Alexandre F.R. Stewart,Benjamin F. Voight,Christina Willenborg,Benjamin J. Wright,David Altshuler,Dan E. Arking,Beverley Balkau,Daniel R. Barnes,Eric Boerwinkle,Bernhard O. Böhm,Amélie Bonnefond,Lori L. Bonnycastle,Dorret I. Boomsma,Stefan R. Bornstein,Yvonne Böttcher,Suzannah Bumpstead,Mary Susan Burnett-Miller,Harry Campbell,Antonio Cao,John C. Chambers,Robert Clark,Francis S. Collins,Josef Coresh,Eco J. C. de Geus,Mariano Dei,Panos Deloukas,Angela Döring,Josephine M. Egan,Roberto Elosua,Luigi Ferrucci,Nita G. Forouhi,Caroline S. Fox,Christopher S. Franklin,Maria Grazia Franzosi,Sophie Gallina,Anuj Goel,J. Graessler,Harald Grallert,Andreas Greinacher,David Hadley,Alistair S. Hall,Anders Hamsten,Caroline Hayward,Simon Heath,Christian Herder,Georg Homuth,Jouke-Jan Hottenga,Rachel Hunter-Merrill,Thomas Illig,Anne U. Jackson,Antti Jula,Marcus E. Kleber,Christopher W. Knouff,Augustine Kong,Jaspal S. Kooner,Anna Köttgen,Peter Kovacs,Knut Krohn,Brigitte Kühnel,Johanna Kuusisto,Markku Laakso,Mark Lathrop,Cécile Lecoeur,Man Li,Mingyao Li,Ruth J. F. Loos,Jian'an Luan,Valeriya Lyssenko,Reedik Mägi,Patrik K. E. Magnusson,Anders Mälarstig,Massimo Mangino,María Teresa Martínez-Larrad,Winfried März,Wendy L. McArdle,Ruth McPherson,Christa Meisinger,Thomas Meitinger,Olle Melander,Karen L. Mohlke,Vincent Mooser,Mario A. Morken,Narisu Narisu,David M. Nathan,Matthias Nauck,Christopher J. O'Donnell,Konrad Oexle,Nazario Olla,James S. Pankow,Felicity Payne,John F. Peden,Nancy L. Pedersen,Leena Peltonen,Markus Perola,Markus Perola,Ozren Polasek,Eleonora Porcu,Daniel J. Rader,Wolfgang Rathmann,Samuli Ripatti,Samuli Ripatti,Ghislain Rocheleau,Michael Roden,Igor Rudan,Veikko Salomaa,Richa Saxena,David Schlessinger,Heribert Schunkert,Peter Schwarz,Udo Seedorf,Elizabeth Selvin,Manuel Serrano-Ríos,Peter Shrader,Angela Silveira,David S. Siscovick,Kjioung Song,Tim D. Spector,Kari Stefansson,Valgerdur Steinthorsdottir,David P. Strachan,Rona J. Strawbridge,Michael Stumvoll,Ida Surakka,Ida Surakka,Amy J. Swift,Toshiko Tanaka,Alexander Teumer,Gudmar Thorleifsson,Unnur Thorsteinsdottir,Anke Tönjes,Gianluca Usala,Veronique Vitart,Henry Völzke,Henri Wallaschofski,Dawn M. Waterworth,Hugh Watkins,H.-Erich Wichmann,Sarah H. Wild,Gonneke Willemsen,Gordon H. Williams,James F. Wilson,Juliane Winkelmann,Alan F. Wright,Carina Zabena,Jing Hua Zhao,Stephen E. Epstein,Jeanette Erdmann,Hakon Hakonarson,Sekar Kathiresan,Kay-Tee Khaw,Robert Roberts,Nilesh J. Samani,Mark D. Fleming,Robert Sladek,Gonçalo R. Abecasis,Michael Boehnke,Philippe Froguel,Leif Groop,Mark I. McCarthy,W. H. Linda Kao,Jose C. Florez,Manuela Uda,Nicholas J. Wareham,Inês Barroso,James B. Meigs +179 more
TL;DR: This article calculated net reclassification of diabetes mellitus patients using a database of patients diagnosed with type 2 diabetes over a 12-month period and found that the number of patients with diabetes decreases with age and disease progression.
Journal ArticleDOI
New estimates and a decomposition of provincial productivity change in China
TL;DR: In this paper, the authors compute and decompose provincial-level Fare-Primont TFP indexes for the period 1978 to 2010 and find evidence of rapid TFP growth mostly due to technical change, but with changes in scale-mix efficiency also playing a supplementary role.
Journal ArticleDOI
Development of the Initial Surveys for the All of Us Research Program
Robert M. Cronin,Rebecca N Jerome,Brandy Mapes,Regina Andrade,Rebecca Johnston,Jennifer E. Ayala,David G. Schlundt,Kemberlee Bonnet,Sunil Kripalani,Kathryn Goggins,Kathryn Goggins,Kenneth A. Wallston,Mick P. Couper,Michael R. Elliott,Paul A. Harris,Mark Begale,Fatima Munoz,Maria Lopez-Class,David Cella,David M. Condon,Mona AuYoung,Kathleen M. Mazor,Steve Mikita,Michael Manganiello,Nicholas Borselli,Stephanie L. Fowler,Joni L. Rutter,Joshua C. Denny,Elizabeth W. Karlson,Brian K. Ahmedani,Christopher J. O'Donnell +30 more
TL;DR: The process used to develop and refine the initial three surveys for the All of Us Research Program, building a national longitudinal cohort and collecting data from multiple information sources to advance precision medicine is reported.
Journal ArticleDOI
Meta-analysis of genome-wide association studies of HDL cholesterol response to statins
Iris Postmus,Helen R. Warren,Stella Trompet,Benoit J. Arsenault,Christy L. Avery,Joshua C. Bis,Daniel I. Chasman,Daniel I. Chasman,Catherine E. de Keyser,Harshal Deshmukh,Daniel S. Evans,QiPing Feng,Xiaohui Li,Roelof A.J. Smit,Albert V. Smith,Fangui Sun,Kent D. Taylor,Alice M. Arnold,Michael R. Barnes,Bryan J. Barratt,John Betteridge,S. Matthijs Boekholdt,Eric Boerwinkle,Brendan M. Buckley,Y. D.I. Chen,Anton J. M. de Craen,Steven R. Cummings,Joshua C. Denny,Marie-Pierre Dubé,Paul N. Durrington,Gudny Eiriksdottir,Ian Ford,Xiuqing Guo,Tamara B. Harris,Susan R. Heckbert,Susan R. Heckbert,Albert Hofman,G. Kees Hovingh,John J. P. Kastelein,L. J. Launer,Ching-Ti Liu,Yongmei Liu,Thomas Lumley,Thomas Lumley,Paul M. McKeigue,Patricia B. Munroe,Andrew Neil,Deborah A. Nickerson,Fredrik Nyberg,Fredrik Nyberg,Eoin O'Brien,Christopher J. O'Donnell,Christopher J. O'Donnell,Wendy Post,Neil R Poulter,Ramachandran S. Vasan,Kenneth Rice,Stephen S. Rich,Fernando Rivadeneira,Naveed Sattar,Peter S. Sever,Sue Shaw-Hawkins,Denis C. Shields,P. Eline Slagboom,Nicholas L. Smith,Nicholas L. Smith,Joshua D. Smith,Nona Sotoodehnia,Nona Sotoodehnia,Alice Stanton,Alice Stanton,David J. Stott,Bruno H. Stricker,Til Stürmer,André G. Uitterlinden,Wei-Qi Wei,Rudi G. J. Westendorp,Eric A. Whitsel,Kerri L. Wiggins,Russell A. Wilke,Christie M. Ballantyne,Helen M. Colhoun,L. Adrienne Cupples,Oscar H. Franco,Vilmundur Gudnason,Graham A. Hitman,Colin N. A. Palmer,Bruce M. Psaty,Bruce M. Psaty,Paul M. Ridker,Jeanette M. Stafford,Charles M. Stein,Jean-Claude Tardif,Mark J. Caulfield,J. Wouter Jukema,Jerome I. Rotter,Ronald M. Krauss +96 more
TL;DR: CETP may be the only detectable locus with common genetic variants that influence HDL-C response to statin treatment substantially in individuals of European descent, and there is evidence that this pharmacogenetic effect is independent of its association with baseline LDL-C levels.