M
Matthew Moll
Researcher at Brigham and Women's Hospital
Publications - 72
Citations - 929
Matthew Moll is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 8, co-authored 38 publications receiving 439 citations. Previous affiliations of Matthew Moll include Penn State Milton S. Hershey Medical Center & Boston University.
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Journal ArticleDOI
A Heteromeric Plastidic Pyruvate Kinase Complex Involved in Seed Oil Biosynthesis in Arabidopsis
TL;DR: The identified pyruvate kinase catalyzes a crucial step in the conversion of photosynthate into oil, suggesting a preferred plastid route from its substrate phosphoenolpyruvates to fatty acids.
Journal ArticleDOI
COPDGene® 2019: Redefining the Diagnosis of Chronic Obstructive Pulmonary Disease.
Katherine E Lowe,Elizabeth A. Regan,Antonio Anzueto,Erin Austin,John H. M. Austin,Terri H. Beaty,Panayiotis V. Benos,Christopher J. Benway,Surya P. Bhatt,Eugene R. Bleecker,Sandeep Bodduluri,Jessica Bon,Jessica Bon,Aladin M. Boriek,Adel Boueiz,Russell P. Bowler,Matthew J. Budoff,Richard Casaburi,Peter J. Castaldi,Jean-Paul Charbonnier,Michael H. Cho,Alejandro P. Comellas,Douglas Conrad,Corinne Costa Davis,Gerard J. Criner,Douglas Curran-Everett,Jeffrey L. Curtis,Dawn L. DeMeo,Alejandro A. Diaz,Mark T. Dransfield,Jennifer G. Dy,Ashraf Fawzy,Margaret Fleming,Eric Flenaugh,Marilyn G. Foreman,Spyridon Fortis,Hirut T. Gebrekristos,Sarah Schmidt Grant,Philippe Grenier,Tian Gu,Abhya Gupta,MeiLan K. Han,Nicola A. Hanania,Nadia N. Hansel,Lystra P. Hayden,Craig P. Hersh,Brian D. Hobbs,Eric A. Hoffman,James C. Hogg,John E. Hokanson,Karin F. Hoth,Albert Hsiao,Stephen M. Humphries,Kathleen Jacobs,Francine L. Jacobson,Ella A. Kazerooni,Victor Kim,Woo Jin Kim,Gregory L. Kinney,Harald Koegler,Sharon M. Lutz,David A. Lynch,Neil R. MacIntye,Barry J. Make,Nathaniel Marchetti,Fernando J. Martinez,Diego J. Maselli,Anne M. Mathews,Meredith C. McCormack,Merry-Lynn McDonald,Charlene McEvoy,Matthew Moll,Sarah S. Molye,Susan Murray,Hrudaya Nath,John D. Newell,John D. Newell,Mariaelena Occhipinti,Matteo Paoletti,Trisha M. Parekh,Massimo Pistolesi,Katherine A. Pratte,Nirupama Putcha,M.F. Ragland,Joseph M. Reinhardt,Stephen I. Rennard,Stephen I. Rennard,Richard Rosiello,James C. Ross,Harry B. Rossiter,Harry B. Rossiter,Ingo Ruczinski,Raúl San José Estépar,Frank C. Sciurba,Jessica C. Sieren,Harjinder Singh,Xavier Soler,Xavier Soler,Robert M. Steiner,Matthew Strand,William W. Stringer,Ruth Tal-Singer,Byron Thomashow,Gonzalo Vegas Sanchez-Ferrero,John W. Walsh,Emily S. Wan,Emily S. Wan,George R. Washko,J. Michael Wells,Chris H. Wendt,Gloria Westney,Ava C. Wilson,Robert A. Wise,Andrew Yen,Kendra A. Young,Jeong H. Yun,Edwin K. Silverman,James D. Crapo +117 more
TL;DR: A substantial portion of smokers with respiratory symptoms and imaging abnormalities do not manifest spirometric obstruction as defined by population normals, and these individuals are at significant risk of death and spirometric disease progression.
Journal ArticleDOI
A linear prognostic score based on the ratio of interleukin-6 to interleukin-10 predicts outcomes in COVID-19.
Oliver J. McElvaney,Oliver J. McElvaney,Brian D. Hobbs,Dandi Qiao,Oisín F. McElvaney,Oisín F. McElvaney,Matthew Moll,Natalie L McEvoy,Jennifer Clarke,Eoin O'Connor,Seán Walsh,Michael H. Cho,Gerard F. Curley,Gerard F. Curley,Noel G. McElvaney,Noel G. McElvaney +15 more
TL;DR: The relationship between the ratio of interleukin (IL)-6 to IL-10 and clinical outcome in 80 patients hospitalized for COVID-19 was studied, and a simple 5-point linear score predictor of clinical outcome was created, the Dublin-Boston score.
Journal ArticleDOI
Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data
Pierrick Wainschtein,Deepti Jain,Zhili Zheng,Stella Aslibekyan,Diane M. Becker,Wenjian Bi,Jennifer A. Brody,Jenna C. Carlson,Adolfo Correa,Margaret Mengmeng Du,Lindsay Fernández-Rhodes,Kendra Ferrier,Misa Graff,Jiang He,Nancy L. Heard-Costa,Heather M. Highland,Joel N. Hirschhorn,Candace M Howard-Claudio,Carmen R. Isasi,Rebecca D. Jackson,Jicai Jiang,Roby Joehanes,Anne E. Justice,Rita R. Kalyani,Sharon L.R. Kardia,Ethan M. Lange,Meryl S. LeBoff,Seunggeun Lee,Xihao Li,Zilin Li,Elise Lim,Danyu Lin,Xihong Lin,Simin Liu,Ying Chang Lu,Joanna Manson,Lisa A. Martin,Caitlin P. McHugh,Julie L. Mikulla,Solomon K. Musani,Maggie C.Y. Ng,Deborah A. Nickerson,Nicholette D. Palmer,James C. Perry,Ulrike Peters,Michael Preuss,Qibin Qi,Laura M. Raffield,Laura J. Rasmussen-Torvik,Alexander P. Reiner,Emily M. Russell,Colleen M. Sitlani,Jennifer A. Smith,Cassandra N. Spracklen,Tao Wang,Zhe Wang,Jennifer Wessel,Hanfei Xu,Mohammadi Yaser,Sachiko Yoneyama,Kendra A. Young,Jingwen Zhang,Xinruo Zhang,Hufeng Zhou,Xiaofeng Zhu,Sebastian Zoellner,Namiko Abe,Gonçalo R. Abecasis,François Aguet,Laura Almasy,Álvaro Alonso,Seth A. Ament,Peter Anderson,Pramod Anugu,Deborah Applebaum-Bowden,Kristin G. Ardlie,Dan E. Arking,Allison E. Ashley-Koch,Tim Assimes,Paul L. Auer,Dimitrios Avramopoulos,Najib T. Ayas,Adithya Balasubramanian,John Barnard,Kathleen C. Barnes,Ronald G. Barr,Emily Barron-Casella,Lucas Barwick,Terri H. Beaty,Gerald Beck,Lewis C. Becker,Rebecca L. Beer,Amber L. Beitelshees,Emelia J. Benjamin,Takis Benos,Marcos Bezerra,Lawrence F. Bielak,Joshua A Bis,Thomas W. Blackwell,John Blangero,Donald W. Bowden,Russell P. Bowler,Ulrich Broeckel,Jai G. Broome,Deborah L. Brown,Karen L. Bunting,Esteban G. Burchard,Carlos Bustamante,Erin J Buth,Brian E. Cade,Jonathan Cardwell,Vincent J. Carey,Julie Carrier,April P Carson,Cara L. Carty,Richard Casaburi,Juan Pablo Casas Romero,James M. Casella,Peter J. Castaldi,Mark Chaffin,Christy Y. P. Chang,Yi-Cheng Chang,Sameer Chavan,Bo Chen,Wei-Min Chen,Mi Ae Cho,Seung Hoan Choi,Lee-Ming Chuang,Ren-Hua Chung,C. Clish,Suzy C. Comhair,Matthew P. Conomos,Elaine Cornell,Carolyn J. Crandall,J. A. Crapo,Joanne E. Curran,Jeffrey R. Curtis,Brian Custer,Coleen M. Damcott,Dawood Darbar,Sean David,Colleen P. Davis,Michelle Daya,L. de las Fuentes,Paul S. de Vries,Michael DeBaun,Ranjan Deka,Dawn L. DeMeo,Scott Devine,Huyen Dinh,Harshavardhan Doddapaneni,Qing Duan,Shannon Dugan-Perez,Ravindranath Duggirala,J. Peter Durda,Susan K. Dutcher,Charles B. Eaton,Lynette Ekunwe,A. El Boueiz,Leslie S. Emery,Serpil C. Erzurum,Charles D. Farber,Jesse Farek,Tasha E. Fingerlin,Matthew Flickinger,Nora Franceschini,Christian D. Frazar,Mao Fu,Stephanie M. Fullerton,Lucinda Fulton,Stacey Gabriel,Weiniu Gan,Shanshan Gao,Yan Gao,Margery Gass,Heather Geiger,Bruce Gelb,M. Geraci,Soren Germer,Robert E. Gerszten,Auyon J. Ghosh,Richard Gibbs,Christopher R. Gignoux,M. Ruban Gladwin,David E. Glahn,Stephanie M. Gogarten,Da-Wei Gong,Harald H.H. Gőring,Sharon L. Graw,Kathryn J. Gray,Daniel Grine,Colin Gross,C. Charles Gu,Yue Guan,Namrata Gupta,David M. Haas,Jeffrey Haessler,Michael N. Hall,Yi Han,Patrick J. Hanly,Daniel N. Harris,Nicola L. Hawley,Benjamin D. Heavner,David Herrington,Craig P. Hersh,Bertha Hidalgo,James E. Hixson,Brian D. Hobbs,John Hokanson,Elliot Hong,Karin F. Hoth,Chao A. Hsiung,Jianhong Hu,Yi Jen Hung,Haley Huston,Chii-Min Hwu,Marguerite R. Irvin,Cashell E. Jaquish,Jill M. Johnsen,Andrew Johnson,Craig Johnson,Richard Karl. Johnston,Kimberly Jones,Hyun Min Kang,Robert Kaplan,Shannon Jeanne Kelly,Eimear E. Kenny,Michael Kessler,Alyna T. Khan,Ziad Khan,Wonji Kim,John Kimoff,Greg Kinney,Barbara A. Konkle,Holly B. Kramer,Christoph Lange,Jiwon Lee,Sandra L. Lee,Wen-Jane Lee,Jonathon LeFaive,David K. Levine,Daniel Levy,Joshua P. Lewis,Xiaohui Li,Yun Li,Henry J. Lin,Honghuang Lin,Yongmei Liu,Yu Liu,Kathryn L. Lunetta,James Luo,Ulysses J. Magalang,Michael P. Mahaney,Barry J. Make,Ani Manichaikul,Alisa K. Manning,Melissa A. Marton,Susan Mathai,Susanne May,Patrick F. McArdle,Sean K. McFarland,Daniel J. McGoldrick,Becky McNeil,Hao Mei,J.R. Meigs,Vipin Menon,Luisa Mestroni,Ginger A. Metcalf,Deborah A. Meyers,Emmanuel Mignot,Nancy Min,Mollie A. Minear,Ryan L. Minster,Matthew Moll,Zeineen Momin,May E. Montasser,Courtney G. Montgomery,Donna M. Muzny,Josyf C. Mychaleckyj,Girish N. Nadkarni,Rakhi Naik,Take Naseri,Pradeep Natarajan,Sergei Nekhai,Sarah C. Nelson,Bonnie Neltner,Caitlin E. Nessner,Osuji Nkechinyere,T. O’Connor,Heather M. Ochs-Balcom,Geoffrey Okwuonu,Allan Pack,David T. Paik,James S. Pankow,George J. Papanicolaou,Cora Parker,Gina M. Peloso,Juan M. Peralta,Marco V Perez,Patricia A. Peyser,L. Phillips,Jacob Pleiness,Toni I. Pollin,Wendy S. Post,Julia Powers Becker,Meher Preethi Boorgula,Pankaj Qasba,Dandi Qiao,Zhaohui S. Qin,Nicholas Rafaels,Mahitha Rajendran,D. C. Rao,Aakrosh Ratan,Robert M. Reed,Catherine Reeves,Muagututi‘a Sefuiva Reupena,Kenneth Rice,Rébecca Robillard,Nicolas Robine,Carolina Roselli,Ingo Ruczinski,Alexi M Runnels,Pamela Russell,Sarah E. Ruuska,Kathleen A. Ryan,Ester Cerdeira Sabino,Danish Saleheen,Shabnam Salimi,Sejal Salvi,Steven L. Salzberg,Kevin Sandow,Vijay G. Sankaran,Jireh Santibanez,Karen Schwander,David A. Schwartz,Frank C. Sciurba,Christine E. Seidman,Jonathan Seidman,Vivien A. Sheehan,Stephanie Sherman,Amol C. Shetty,Aniket Shetty,Wayne H-H Sheu,Brian H. Silver,Edwin K. Silverman,Robert Skomro,Josh Smith,Tanja Smith,Sylvia Smoller,Beverly M. Snively,Michael Snyder,Tamar Sofer,Nona Sotoodehnia,Adrienne M. Stilp,Garrett R. Storm,Elizabeth A. Streeten,Jessica Lasky-Su,Yun Ju Sung,Jody S. Sylvia,Adam A. Szpiro,Daniel Taliun,Hua Tang,Margaret A. Taub,Kent D. Taylor,Matthew D. Taylor,Simeon I. Taylor,Marilyn I. Telen,Timothy A. Thornton,M. Threlkeld,Lesley F. Tinker,David L. Tirschwell,Sarah A. Tishkoff,Hemant K. Tiwari,Catherine Tong,Russell P. Tracy,Michael Y. Tsai,Dhananjay Vaidya,David Van Den Berg,Peter VandeHaar,Scott I. Vrieze,Tarik Walker,Robert B. Wallace,Avram D. Walts,Fei Fei Wang,Heming Wang,Jiongming Wang,Karol E. Watson,Jennifer Watt,Daniel E. Weeks,Joshua S. Weinstock,Scott T. Weiss,Lu-Chen Weng,Cristen J. Willer,Kayleen Williams,L. Keoki Williams,Carla F. Wilson,James F. Wilson,Lara Heermans Winterkorn,Quenna Wong,Joseph M. Wu,Huichun Xu,Ivana V. Yang,Ketian Yu,Seyedeh M. Zekavat,Yingze Zhang,Snow Xueyan Zhao,Wei Zhao,Michael C. Zody,L. Adrienne Cupples,Aladdin H. Shadyab,Barbara McKnight,Benjamin Shoemaker,Braxton D. Mitchell,Bruce M. Psaty,Charles Kooperberg,Ching-Ti Liu,Christine M. Albert,Dan M. Roden,Daniel I. Chasman,Donald M. Lloyd-Jones,Donna K. Arnett,Elizabeth A. Regan,Eric Boerwinkle,Jerome I. Rotter,Jeffrey R. O'Connell,Lisa R. Yanek,Mariza de Andrade,Matthew A. Allison,M. McDonald,Mina K. Chung,Myriam Fornage,Nathalie Chami,Nicholas L. Smith,Patrick T. Ellinor,Ramachandran S. Vasan,Rasika A. Mathias,Ruth J. F. Loos,Stephen S. Rich,Steven A. Lubitz,Susan R. Heckbert,Susan Redline,Xiuqing Guo,Y. D. Chen,Cecelia A. Laurie,Ryan D. Hernandez,Stephen T. McGarvey,Michael E. Goddard,Cathy C. Laurie,Kari E. North,Leslie A. Lange,Bruce S. Weir,Loic Yengo,Jian Yang,Peter M. Visscher +453 more
TL;DR: The results imply that rare variants, in particular those in regions of low linkage disequilibrium, are a major source of the still missing heritability of complex traits and disease.