F
Falk Hildebrand
Researcher at Norwich University
Publications - 87
Citations - 16383
Falk Hildebrand is an academic researcher from Norwich University. The author has contributed to research in topics: Microbiome & Metagenomics. The author has an hindex of 32, co-authored 74 publications receiving 11776 citations. Previous affiliations of Falk Hildebrand include Norwich Research Park & University of Sussex.
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Journal ArticleDOI
Richness of human gut microbiome correlates with metabolic markers
Trine Nielsen,Junjie Qin,Edi Prifti,Falk Hildebrand,Gwen Falony,Mathieu Almeida,Manimozhiyan Arumugam,Jean-Michel Batto,Sean Kennedy,Pierre Leonard,Junhua Li,Kristoffer Sølvsten Burgdorf,Niels Grarup,Torben Jørgensen,Torben Jørgensen,Torben Jørgensen,Ivan Brandslund,Henrik Nielsen,Agnieszka S. Juncker,Marcelo Bertalan,Florence Levenez,Nicolas Pons,Simon Rasmussen,Shinichi Sunagawa,Julien Tap,Sebastian Tims,Erwin G. Zoetendal,Søren Brunak,Karine Clément,Karine Clément,Joël Doré,Michiel Kleerebezem,Karsten Kristiansen,Pierre Renault,Thomas Sicheritz-Pontén,Willem M. de Vos,Willem M. de Vos,Jean-Daniel Zucker,Jean-Daniel Zucker,Jean-Daniel Zucker,Jeroen Raes,Torben Hansen,Torben Hansen,Peer Bork,Jun Wang,S. Dusko Ehrlich,Oluf Pedersen +46 more
TL;DR: The authors' classifications based on variation in the gut microbiome identify subsets of individuals in the general white adult population who may be at increased risk of progressing to adiposity-associated co-morbidities.
Journal ArticleDOI
Structure and function of the global ocean microbiome
Shinichi Sunagawa,Luis Pedro Coelho,Samuel Chaffron,Jens Roat Kultima,Karine Labadie,Guillem Salazar,Bardya Djahanschiri,Georg Zeller,Daniel R. Mende,Adriana Alberti,Francisco M. Cornejo-Castillo,Paul I. Costea,Corinne Cruaud,Francesco d'Ovidio,Stefan Engelen,Isabel Ferrera,Josep M. Gasol,Lionel Guidi,Falk Hildebrand,Florian Kokoszka,Cyrille Lepoivre,Gipsi Lima-Mendez,Julie Poulain,Bonnie T. Poulos,Marta Royo-Llonch,Hugo Sarmento,Sara Vieira-Silva,Céline Dimier,Marc Picheral,Sarah Searson,Stefanie Kandels-Lewis,Tara Oceans Coordinators,Chris Bowler,Colomban de Vargas,Gabriel Gorsky,Nigel Grimsley,Pascal Hingamp,Daniele Iudicone,Olivier Jaillon,Fabrice Not,Hiroyuki Ogata,Stephane Pesant,Sabrina Speich,Lars Stemmann,Matthew B. Sullivan,Jean Weissenbach,Patrick Wincker,Eric Karsenti,Jeroen Raes,Silvia G. Acinas,Peer Bork +50 more
TL;DR: This work identifies ocean microbial core functionality and reveals that >73% of its abundance is shared with the human gut microbiome despite the physicochemical differences between these two ecosystems.
Journal ArticleDOI
Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota
Kristoffer Forslund,Falk Hildebrand,Falk Hildebrand,Trine Nielsen,Gwen Falony,Gwen Falony,Shinichi Sunagawa,Edi Prifti,Sara Vieira-Silva,Sara Vieira-Silva,Valborg Gudmundsdottir,Helle Krogh Pedersen,Manimozhiyan Arumugam,Karsten Kristiansen,Anita Y. Voigt,Anita Y. Voigt,Henrik Vestergaard,Rajna Hercog,Paul I. Costea,Jens Roat Kultima,Junhua Li,Torben Jørgensen,Torben Jørgensen,Florence Levenez,Joël Doré,H. Bjørn Nielsen,Søren Brunak,Søren Brunak,Jeroen Raes,Jeroen Raes,Jeroen Raes,Torben Hansen,Torben Hansen,Jun Wang,S. Dusko Ehrlich,S. Dusko Ehrlich,Peer Bork,Oluf Pedersen +37 more
TL;DR: A unified signature of gut microbiome shifts in T2D with a depletion of butyrate-producing taxa is reported, highlighting the need to disentangle gut microbiota signatures of specific human diseases from those of medication.
Journal ArticleDOI
Human gut microbes impact host serum metabolome and insulin sensitivity
Helle Krogh Pedersen,Valborg Gudmundsdottir,Henrik Nielsen,Tuulia Hyötyläinen,Tuulia Hyötyläinen,Trine G. Nielsen,Benjamin A. H. Jensen,Kristoffer Forslund,Falk Hildebrand,Falk Hildebrand,Edi Prifti,Edi Prifti,Gwen Falony,Florence Levenez,Joël Doré,Ismo Mattila,Ismo Mattila,Damian R. Plichta,Päivi Pöhö,Päivi Pöhö,Lars Hellgren,Manimozhiyan Arumugam,Shinichi Sunagawa,Sara Vieira-Silva,Torben Jørgensen,Torben Jørgensen,Jacob Bak Holm,Kajetan Trošt,Karsten Kristiansen,Susanne Brix,Jeroen Raes,Jeroen Raes,Jun Wang,Torben Hansen,Torben Hansen,Peer Bork,Søren Brunak,Søren Brunak,Matej Orešič,Matej Orešič,Matej Orešič,S. Dusko Ehrlich,S. Dusko Ehrlich,Oluf Pedersen +43 more
TL;DR: It is shown how the human gut microbiome impacts the serum metabolome and associates with insulin resistance in 277 non-diabetic Danish individuals and suggested that microbial targets may have the potential to diminish insulin resistance and reduce the incidence of common metabolic and cardiovascular disorders.
Journal ArticleDOI
Structure and function of the global topsoil microbiome.
Mohammad Bahram,Mohammad Bahram,Mohammad Bahram,Falk Hildebrand,Sofia K. Forslund,Sofia K. Forslund,Jennifer L. Anderson,Nadejda A. Soudzilovskaia,Peter M. Van Bodegom,Johan Bengtsson-Palme,Sten Anslan,Sten Anslan,Luis Pedro Coelho,Helery Harend,Jaime Huerta-Cepas,Marnix H. Medema,Mia R. Maltz,Sunil Mundra,Pål Axel Olsson,Mari Pent,Sergei Põlme,Shinichi Sunagawa,Martin Ryberg,Leho Tedersoo,Peer Bork,Peer Bork +25 more
TL;DR: It is shown that bacterial, but not fungal, genetic diversity is highest in temperate habitats and that microbial gene composition varies more strongly with environmental variables than with geographic distance, and that the relative contributions of these microorganisms to global nutrient cycling varies spatially.