G
Gemma Lombardi
Researcher at University of Florence
Publications - 50
Citations - 1290
Gemma Lombardi is an academic researcher from University of Florence. The author has contributed to research in topics: Medicine & Frontotemporal dementia. The author has an hindex of 11, co-authored 30 publications receiving 811 citations.
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Journal ArticleDOI
Presymptomatic cognitive and neuroanatomical changes in genetic frontotemporal dementia in the Genetic Frontotemporal dementia Initiative (GENFI) study: a cross-sectional analysis
Jonathan D. Rohrer,Jennifer M. Nicholas,Jennifer M. Nicholas,David M. Cash,John C. van Swieten,Elise G.P. Dopper,Lize C. Jiskoot,Rick van Minkelen,Serge A.R.B. Rombouts,M. Jorge Cardoso,Shona Clegg,Miklos Espak,Simon Mead,David L. Thomas,Enrico De Vita,Mario Masellis,Sandra E. Black,Morris Freedman,Ron Keren,Bradley J. MacIntosh,Ekaterina Rogaeva,David F. Tang-Wai,Maria Carmela Tartaglia,Robert Laforce,Fabrizio Tagliavini,Pietro Tiraboschi,Veronica Redaelli,Sara Prioni,Marina Grisoli,Barbara Borroni,Alessandro Padovani,Daniela Galimberti,Elio Scarpini,Andrea Arighi,Giorgio G. Fumagalli,James B. Rowe,Ian Coyle-Gilchrist,Caroline Graff,Caroline Graff,Marie Fallström,Vesna Jelic,Vesna Jelic,Anne Kinhult Ståhlbom,Anne Kinhult Ståhlbom,Christin Andersson,Christin Andersson,Håkan Thonberg,Håkan Thonberg,Lena Lilius,Giovanni B. Frisoni,Giuliano Binetti,Michela Pievani,Martina Bocchetta,Luisa Benussi,Roberta Ghidoni,Elizabeth Finger,Sandro Sorbi,Benedetta Nacmias,Gemma Lombardi,Cristina Polito,Jason D. Warren,Sebastien Ourselin,Nick C. Fox,Martin N. Rossor +63 more
TL;DR: Structural imaging and cognitive changes can be identified 5-10 years before expected onset of symptoms in asymptomatic adults at risk of genetic frontotemporal dementia, which could help to define biomarkers that can stage presymPTomatic disease and track disease progression.
Journal ArticleDOI
Prevalence of sleep disturbances in mild cognitive impairment and dementing disorders: a multicenter Italian clinical cross-sectional study on 431 patients.
Biancamaria Guarnieri,Fulvio Adorni,Massimo Musicco,Ildebrando Appollonio,Enrica Bonanni,Paolo Caffarra,Carlo Caltagirone,G Cerroni,L. Concari,Filomena I.I. Cosentino,S. Ferrara,S. Fermi,Raffaele Ferri,Giorgio Gelosa,Gemma Lombardi,Debora Mazzei,S. Mearelli,Elisa Morrone,Luigi Murri,Flavio Nobili,Stefano Passero,Roberta Perri,Raffaele Rocchi,P. Sucapane,Gloria Tognoni,Silvia Zabberoni,Sandro Sorbi +26 more
TL;DR: A careful clinical evaluation of sleep disorders should be performed routinely in the clinical setting of persons with cognitive decline, and Instrumental supports should be used only in selected patients.
Journal ArticleDOI
Age at symptom onset and death and disease duration in genetic frontotemporal dementia: an international retrospective cohort study.
Katrina M. Moore,Jennifer M. Nicholas,Murray Grossman,Corey T. McMillan,David J. Irwin,Lauren Massimo,Vivianna M. Van Deerlin,Jason D. Warren,Nick C. Fox,Martin N. Rossor,Simon Mead,Martina Bocchetta,Bradley F. Boeve,David S. Knopman,Neill Graff-Radford,Leah K. Forsberg,Rosa Rademakers,Zbigniew K. Wszolek,John C. van Swieten,Lize C. Jiskoot,Lieke H.H. Meeter,Elise G.P. Dopper,Janne M. Papma,Julie S. Snowden,Jennifer A. Saxon,Matthew Jones,Stuart Pickering-Brown,Isabelle Le Ber,Agnès Camuzat,Alexis Brice,Paola Caroppo,Roberta Ghidoni,Michela Pievani,Luisa Benussi,Giuliano Binetti,Bradford C. Dickerson,Diane Lucente,Samantha Krivensky,Caroline Graff,Linn Öijerstedt,Marie Fallström,Håkan Thonberg,Nupur Ghoshal,John C. Morris,Barbara Borroni,Alberto Benussi,Alessandro Padovani,Daniela Galimberti,Elio Scarpini,Giorgio G. Fumagalli,Giorgio G. Fumagalli,Ian R. Mackenzie,Ging-Yuek Robin Hsiung,Pheth Sengdy,Adam L. Boxer,Howie Rosen,Joanne Taylor,Matthis Synofzik,Matthis Synofzik,Carlo Wilke,Carlo Wilke,Patricia Sulzer,Patricia Sulzer,John R. Hodges,Glenda M. Halliday,John B.J. Kwok,Raquel Sánchez-Valle,Albert Lladó,Sergi Borrego-Écija,Isabel Santana,Maria Rosário Almeida,Miguel Tábuas-Pereira,Fermin Moreno,Myriam Barandiaran,Begoña Indakoetxea,Johannes Levin,Johannes Levin,Adrian Danek,James B. Rowe,Thomas E. Cope,Markus Otto,Sarah Anderl-Straub,Alexandre de Mendonça,Carolina Maruta,Mario Masellis,Sandra E. Black,Philippe Couratier,Géraldine Lautrette,Edward D. Huey,Sandro Sorbi,Benedetta Nacmias,Robert Laforce,Marie Pier L. Tremblay,Rik Vandenberghe,Philip Van Damme,Philip Van Damme,Emily Rogalski,Sandra Weintraub,Alexander Gerhard,Alexander Gerhard,Chiadi U. Onyike,Simon Ducharme,Sokratis G. Papageorgiou,Adeline Su Lyn Ng,Amy Brodtmann,Elizabeth Finger,Rita Guerreiro,Jose Bras,Jonathan D. Rohrer,Carolin Heller,Rhian S Convery,Ione O.C. Woollacott,Rachelle Shafei,Jonathan Graff-Radford,David T.W. Jones,Christina Dheel,Rodolfo Savica,Maria I. Lapid,Matt Baker,Julie A. Fields,Ralitza H. Gavrilova,Kimiko Domoto-Reilly,Jackie M. Poos,Emma L. van der Ende,Jessica L. Panman,Laura Donker Kaat,Harro Seelaar,Anna Richardson,Giovanni B. Frisoni,Anna Mega,Silvia Fostinelli,Huei Hsin Chiang,Antonella Alberici,Andrea Arighi,Chiara Fenoglio,Hilary W. Heuer,Bruce L. Miller,Anna Karydas,Jamie Fong,Maria João Leitão,Beatriz Santiago,Diana Duro,Carlos Ferreira,Alazne Gabilondo,Maria de Arriba,Mikel Tainta,Miren Zulaica,Catarina S. Ferreira,Elisa Semler,Albert C. Ludolph,Bernhard Landwehrmeyer,Alexander E Volk,Gabriel Miltenberger,Ana Verdelho,Sónia Afonso,Maria Carmela Tartaglia,Morris Freedman,Ekaterina Rogaeva,Camilla Ferrari,Irene Piaceri,Valentina Bessi,Gemma Lombardi,Frédéric St-Onge,Marie Claire Doré,Rose Bruffaerts,Mathieu Vandenbulcke,Jan Van den Stock,M.-Marsel Mesulam,Eileen H. Bigio,Christos Koros,John Papatriantafyllou,Christos Kroupis,Leonidas Stefanis,Christien Shoesmith,Erik Robertson,Giovanni Coppola,Eliana Marisa Ramos,Daniel H. Geschwind +177 more
TL;DR: An international study of age at symptom onset, age at death, and disease duration in individuals with mutations in GRN, MAPT, and C9orf72 to investigate the extent to which variability in age at onset and at death could be accounted for by family membership and the specific mutation carried.
Journal ArticleDOI
Structural magnetic resonance imaging for the early diagnosis of dementia due to Alzheimer's disease in people with mild cognitive impairment
Gemma Lombardi,Giada Crescioli,Enrica Cavedo,Ersilia Lucenteforte,Giovanni Casazza,Alessandro Giacco Bellatorre,Chiara Lista,Giorgio Costantino,Giovanni B. Frisoni,Gianni Virgili,Graziella Filippini +10 more
TL;DR: To assess the diagnostic accuracy of structural magnetic resonance imaging for the early diagnosis of dementia due to Alzheimer's disease in people with MCI, Cochrane Dementia and Cognitive Improvement's Specialised Register and the databases was searched and overall measures of relative accuracy in subgroup analyses were obtained.
Journal ArticleDOI
Functional network resilience to pathology in presymptomatic genetic frontotemporal dementia
Timothy Rittman,Robin J Borchert,Simon Jones,John C. van Swieten,Barbara Borroni,Daniela Galimberti,Mario Masellis,Mario Masellis,Mario Masellis,Maria Carmela Tartaglia,Caroline Graff,Caroline Graff,Fabrizio Tagliavini,Giovanni B. Frisoni,Robert Laforce,Elizabeth Finger,Alexandre de Mendonça,Sandro Sorbi,Jonathan D. Rohrer,James B. Rowe,Sónia Afonso,Maria Rosário Almeida,Sarah Anderl-Straub,Christin Andersson,Anna Antonell,Silvana Archetti,Andrea Arighi,Andrea Arighi,Mircea Balasa,Myriam Barandiaran,Núria Bargalló,Robart Bartha,Benjamin Bender,Luisa Benussi,Valentina Bessi,Giuliano Binetti,Sandra E. Black,Martina Bocchetta,Sergi Borrego-Écija,Jose Bras,Rose Bruffaerts,Paola Caroppo,David M. Cash,Miguel Castelo-Branco,Rhian S Convery,Thomas E. Cope,Maura Cosseddu,Maria de Arriba,Giuseppe Di Fede,Zigor Diaz,Katrina M. Dick,Diana Duro,Chiara Fenoglio,Chiara Fenoglio,Camilla Ferrari,C. Ferreira,Toby Flanagana,Nick C. Fox,Morris Freedman,Giorgio G. Fumagalli,Giorgio G. Fumagalli,Giorgio G. Fumagalli,Alazne Gabilondo,Roberto Gasparotti,Serge Gauthier,Stefano Gazzina,Roberta Ghidoni,Giorgio Giaccone,Ana Gorostidi,Caroline V. Greaves,Rita Guerreiro,Carolin Heller,Tobias Hoegen,Begoña Indakoetxea,Vesna Jelic,Lize C. Jiskoot,Hans-Otto Karnath,Ron Keren,Maria João Leitão,Albert Lladó,Gemma Lombardi,Sandra V. Loosli,Carolina Maruta,Simon Mead,Lieke H.H. Meeter,Gabriel Miltenberger,Rick van Minkelen,Sara Mitchell,Benedetta Nacmias,Mollie Neason,Jennifer M. Nicholas,Linn Öijerstedt,Jaume Olives,Alessandro Padovani,Jessica L. Panman,Janne M. Papma,Michela Pievani,Yolande A.L. Pijnenburg,Enrico Premi,Sara Prioni,Catharina Prix,Rosa Rademakers,Veronica Redaelli,Ekaterina Rogaeva,Pedro Rosa-Neto,Giacomina Rossi,Martin Rosser,Beatriz Santiago,Elio Scarpini,Elio Scarpini,Sonja Schönecker,Elisa Semler,Rachelle Shafei,Christen Shoesmith,Miguel Tábuas-Pereira,Mikel Tainta,Ricardo Taipa,David F. Tang-Wai,David L. Thomas,Håkan Thonberg,Carolyn Timberlake,Pietro Tiraboschi,Philip Vandamme,Mathieu Vandenbulcke,Michele Veldsman,Ana Verdelho,Jorge Villanua,Jason D. Warren,Carlo Wilke,Ione O.C. Woollacott,Elisabeth Wlasich,Henrik Zetterberg,Miren Zulaica +132 more
TL;DR: It is proposed that maintaining the efficient organization of the brain's functional network supports cognitive health even as atrophy and connectivity decline presymptomatically.