J
J. Cooper Roddey
Researcher at University of California, San Diego
Publications - 19
Citations - 3235
J. Cooper Roddey is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Genome-wide association study & Brain size. The author has an hindex of 18, co-authored 19 publications receiving 2878 citations. Previous affiliations of J. Cooper Roddey include Utrecht University.
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Journal ArticleDOI
Identification of common variants associated with human hippocampal and intracranial volumes
Jason L. Stein,Sarah E. Medland,Sarah E. Medland,Alejandro Arias Vasquez,Alejandro Arias Vasquez,Derrek P. Hibar,Rudy E Senstad,Anderson M. Winkler,Anderson M. Winkler,Roberto Toro,Roberto Toro,Katja Appel,Katja Appel,Richard Barteček,Ørjan Bergmann,Manon Bernard,Andrew A. Brown,Dara M. Cannon,M. Mallar Chakravarty,Andrea Christoforou,Andrea Christoforou,Martin Domin,Oliver Grimm,Marisa O. Hollinshead,Marisa O. Hollinshead,Avram J. Holmes,Georg Homuth,Jouke-Jan Hottenga,Camilla Langan,Lorna M. Lopez,Narelle K. Hansell,Kristy S. Hwang,Sungeun Kim,Gonzalo Laje,Phil Lee,Xinmin Liu,Xinmin Liu,Eva Loth,Anbarasu Lourdusamy,Morten Mattingsdal,Sebastian Mohnke,Susana Muñoz Maniega,Kwangsik Nho,Kwangsik Nho,Allison C. Nugent,Carol O'Brien,Martina Papmeyer,Benno Pütz,Adaikalavan Ramasamy,Jerod M. Rasmussen,Mark Rijpkema,Mark Rijpkema,Shannon L. Risacher,J. Cooper Roddey,Emma J. Rose,Mina Ryten,Li Shen,Emma Sprooten,Eric Strengman,Alexander Teumer,Daniah Trabzuni,Jessica A. Turner,Kristel R. van Eijk,Theo G.M. van Erp,Marie-José van Tol,Marie-José van Tol,Marie-José van Tol,Katharina Wittfeld,Christiane Wolf,Saskia Woudstra,André Aleman,Saud Alhusaini,Laura Almasy,Elisabeth B. Binder,David G. Brohawn,Rita M. Cantor,Melanie A. Carless,Aiden Corvin,Michael Czisch,Joanne E. Curran,Gail Davies,Marcio Almeida,Norman Delanty,Norman Delanty,Chantal Depondt,Ravi Duggirala,Thomas D. Dyer,Susanne Erk,Jesen Fagerness,Peter T. Fox,Nelson B. Freimer,Michael Gill,Harald H H Göring,Donald J. Hagler,D. Hoehn,Florian Holsboer,Martine Hoogman,Norbert Hosten,Neda Jahanshad,Matthew P. Johnson,Dalia Kasperaviciute,Jack W. Kent,Peter Kochunov,Peter Kochunov,Jack L. Lancaster,Stephen M. Lawrie,David C. Liewald,René C.W. Mandl,Mar Matarin,Manuel Mattheisen,Eva M. Meisenzahl,Ingrid Melle,Ingrid Melle,Eric K. Moses,Thomas W. Mühleisen,Matthias Nauck,Markus M. Nöthen,Rene L. Olvera,Massimo Pandolfo,G. Bruce Pike,Ralf Puls,Ivar Reinvang,Miguel E. Rentería,Miguel E. Rentería,Marcella Rietschel,Joshua L. Roffman,Natalie A. Royle,Dan Rujescu,Jonathan Savitz,Jonathan Savitz,Hugo G. Schnack,Knut Schnell,Nina Y. Seiferth,Colin Smith,Vidar M. Steen,Vidar M. Steen,Maria del C. Valdés Hernández,Martijn P. van den Heuvel,Nic J.A. van der Wee,Nic J.A. van der Wee,Neeltje E.M. van Haren,Joris A. Veltman,Henry Völzke,Robert Walker,Lars T. Westlye,Christopher D. Whelan,Ingrid Agartz,Dorret I. Boomsma,Gianpiero L. Cavalleri,Anders M. Dale,Anders M. Dale,Srdjan Djurovic,Srdjan Djurovic,Wayne C. Drevets,Wayne C. Drevets,Peter Hagoort,Peter Hagoort,Peter Hagoort,Jeremy Hall,Andreas Heinz,Clifford R. Jack,Tatiana Foroud,Stephanie Le Hellard,Stephanie Le Hellard,Fabio Macciardi,Grant W. Montgomery,Jean-Baptiste Poline,David J. Porteous,Sanjay M. Sisodiya,John M. Starr,Jessika E. Sussmann,Arthur W. Toga,Dick J. Veltman,Henrik Walter,Michael W. Weiner,Joshua C. Bis,M. Arfan Ikram,Albert V. Smith,Vilmundur Gudnason,Christophe Tzourio,Christophe Tzourio,Meike W. Vernooij,Lenore J. Launer,Charles DeCarli,Sudha Seshadri,Ole A. Andreassen,Ole A. Andreassen,Liana G. Apostolova,Mark E. Bastin,John Blangero,Han G. Brunner,Randy L. Buckner,Sven Cichon,Giovanni Coppola,Giovanni Coppola,Greig I. de Zubicaray,Ian J. Deary,Gary Donohoe,Eco J. C. de Geus,Thomas Espeseth,Thomas Espeseth,Guillén Fernández,Guillén Fernández,Guillén Fernández,David C. Glahn,David C. Glahn,Hans J. Grabe,Hans J. Grabe,John Hardy,Hilleke E. Hulshoff Pol,Mark Jenkinson,René S. Kahn,Colm McDonald,Andrew M. McIntosh,Francis J. McMahon,Katie L. McMahon,Andreas Meyer-Lindenberg,Derek W. Morris,Bertram Müller-Myhsok,Thomas E. Nichols,Thomas E. Nichols,Roel A. Ophoff,Roel A. Ophoff,Tomáš Paus,Zdenka Pausova,Brenda W.J.H. Penninx,Steven G. Potkin,Philipp G. Sämann,Andrew J. Saykin,Gunter Schumann,Jordan W. Smoller,Joanna M. Wardlaw,Michael E. Weale,Nicholas G. Martin,Barbara Franke,Barbara Franke,Margaret J. Wright,Paul M. Thompson +237 more
TL;DR: In this article, the authors report genome-wide association meta-analyses and replication for mean bilateral hippocampal, total brain and intracranial volumes from a large multinational consortium.
Journal ArticleDOI
Improved Detection of Common Variants Associated with Schizophrenia by Leveraging Pleiotropy with Cardiovascular-Disease Risk Factors
Ole A. Andreassen,Ole A. Andreassen,Ole A. Andreassen,Srdjan Djurovic,Srdjan Djurovic,Wesley K. Thompson,Andrew J. Schork,Kenneth S. Kendler,Michael Conlon O'Donovan,Dan Rujescu,Thomas Werge,Martijn van de Bunt,Andrew P. Morris,Mark I. McCarthy,J. Cooper Roddey,Linda K. McEvoy,Rahul S. Desikan,Anders M. Dale +17 more
TL;DR: A genetic-pleiotropy-informed method for improving gene discovery with the use of GWAS summary-statistics data and enrichment of SNPs associated with schizophrenia (SCZ) as a function of the association with several CVD risk factors and a corresponding reduction in false discovery rate is presented.
Journal ArticleDOI
All SNPs are not created equal: genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs.
Andrew J. Schork,Wesley K. Thompson,Phillip H. Pham,Phillip H. Pham,Ali Torkamani,Ali Torkamani,J. Cooper Roddey,Patrick F. Sullivan,John R. Kelsoe,Michael Conlon O'Donovan,Helena Furberg,Nicholas J. Schork,Nicholas J. Schork,Nicholas J. Schork,Ole A. Andreassen,Anders M. Dale +15 more
TL;DR: The utility of stratification for improving power of GWAS in complex phenotypes, with increased rejection rates from 20% in height to 300% in schizophrenia with traditional FDR and sFDR both fixed at 0.05 is demonstrated.
Journal ArticleDOI
Alzheimer Disease: Quantitative Structural Neuroimaging for Detection and Prediction of Clinical and Structural Changes in Mild Cognitive Impairment
Linda K. McEvoy,Christine Fennema-Notestine,J. Cooper Roddey,Donald J. Hagler,Dominic Holland,David S. Karow,Christopher J. Pung,James B. Brewer,Anders M. Dale +8 more
TL;DR: Semiautomated, individually specific quantitative MR imaging methods can be used to identify a pattern of regional atrophy in MCI that is predictive of clinical decline and structural loss that may aid in prediction of patient prognosis and increase the efficiency of clinical trials.
Journal ArticleDOI
Improved Detection of Common Variants Associated with Schizophrenia and Bipolar Disorder Using Pleiotropy-Informed Conditional False Discovery Rate
Ole A. Andreassen,Wesley K. Thompson,Andrew J. Schork,Stephan Ripke,Morten Mattingsdal,John R. Kelsoe,Kenneth S. Kendler,Michael Conlon O'Donovan,Dan Rujescu,Thomas Werge,Pamela Sklar,J. Cooper Roddey,Chi-Hua Chen,Linda K. McEvoy,Rahul S. Desikan,Rahul S. Desikan,Srdjan Djurovic,Anders M. Dale +17 more
TL;DR: Together, these findings show the feasibility of genetic pleiotropy-informed methods to improve gene discovery in SCZ and BD and indicate overlapping genetic mechanisms between these two disorders.