J
Jo Spencer
Researcher at King's College London
Publications - 171
Citations - 12045
Jo Spencer is an academic researcher from King's College London. The author has contributed to research in topics: B cell & Antibody. The author has an hindex of 48, co-authored 156 publications receiving 11345 citations. Previous affiliations of Jo Spencer include University College London & Guy's and St Thomas' NHS Foundation Trust.
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Journal ArticleDOI
Biases in Ig λ Light Chain Rearrangements in Human Intestinal Plasma Cells
TL;DR: Out-of-frame rearrangements of IgVλJλ from plasma cells, including those involving the Vλ5 family, have a significant tendency not to involve Jλ1, consistent with the hypothesis that this population includes rearrangement generated by secondary recombination events.
Journal ArticleDOI
Tumour infiltrating T-cells in gastric lymphoma.
TL;DR: Evidence suggests that rather than having anti-tumour activity, TIL's may have a critical role in supporting the progression of B cell lymphomas arising in mucosa associated lymphoid tissue (MAUFtype lymphomas).
Journal ArticleDOI
Defective STAT5 Activation and Aberrant Expression of BCL6 in Naive CD4 T Cells Enhances Follicular Th Cell–like Differentiation in Patients with Granulomatosis with Polyangiitis
Sangmi Kim,Lena Boehme,Louise Nel,Alina Casian,Shirish Sangle,Estefania Nova-Lamperti,Vlad C. Seitan,Jo Spencer,Paul Lavender,David D'Cruz,Susan D. John +10 more
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Journal ArticleDOI
Basic Science208. Stem Cell Factor Expression is Increased in the Skin of Patients with Systemic Sclerosis and Promotes Proliferation and Migration of Fibroblasts in vitro
Sarah Karrar,Xu Shiwen,Joana Nikotorowicz-Buniak,David J. Abraham,Christopher P. Denton,Richard Stratton,Rachel Bayley,Kerry A. Kite,Elizabeth Clay,Jacqueline P. Smith,George D. Kitas,Christopher D. Buckley,Stephen P. Young,Lingying Ye,Libin Zhang,Jane Goodall,Hill Gaston,Huji Xu,Pamela M. K. Lutalo,Yuan Zhao,Lee Meng Choong,Shirish Sangle,Jo Spencer,David D'Cruz,Oliwia Rysnik,Kirsty McHugh,Paul Bowness,Lisa Rump-Goodrich,Derek Mattey,Oksana Kehoe,Jim Middleton,Alison J. Cartwright,Caroline Schmutz,Ayman Askari,David H. Gardner,Louisa E. Jeffery,Karim Raza,David M. Sansom,Martin Fitzpatrick,Graham R. Wallace,Stephen Young,Jacqueline Shaw,Hiroko Hatano,Alberto Cauli,Joanna L. Giles,Alessandro Mathieu,Simon Kollnberger,Steve J. Webster,Lou Ellis,Louise O'Brien,Tim J. Fitzmaurice,Abdul Nazeer Moideen,Laura Evans,Louise Emma Osgood,Anwen Williams,Simon Jones,Chris Thomas,Valerie O'Donnell,Mari Nowell,Lylia Ouboussad,Sinisa Savic,Laura J. Dickie,Janina Hintze,Chi H. Wong,Graham P. Cook,Maya H Buch,Paul Emery,Michael F. McDermott,Sarah A. Hardcastle,Celia L. Gregson,Kevin Deere,George Davey Smith,Paul A Dieppe,Jonathan H Tobias,Elaine M. Dennison,Mark Edwards,Jim Bennett,David Coggon,Keith Palmer,Cyrus Cooper,Daniel F. McWilliams,Adam Young,Patrick Kiely,David A. Walsh,Hilary Taylor,Ian Harding,J. Hutchinson,I. Nelson,Ashley W Blom,Jon Tobias,Emma Clark,Joshua Parker,Marwan Bukhari,Keeranur Jayakumar,Patrick Kiely,Janet Diffin,Mark Lunt,Tarnya Marshall,J. Chipping,Deborah P M Symmons,Suzanne M. Verstappen,James Bluett,John Bowes,Pauline Ho,Neil McHugh,David Buden,Oliver FitzGerald,Anne Barton,John R. Glossop,N B Nixon,Richard D. Emes,P. T. Dawes,William E. Farrell,Derek L. Mattey,Ian C. Scott,S Steer,Seth Seegobin,Anne M. Hinks,Stephen Eyre,Ann W. Morgan,Anthony G. Wilson,Lynne J. Hocking,Paul Wordsworth,Jane Worthington,Andrew Cope,Cathryn M. Lewis,Sandra G. Guerra,Bahja A. Ahmed,David Abraham,Carmen Fonseca,J. E.M. Robinson,John Taylor,Lubna Haroon Rashid,Edward Flynn,John D. Isaacs,Jennifer H. Barrett,Belinda Kingston,Mohamed Ahmed,John R. Kirwan,Robert Marshall,Kate E. Chapman,Robert Pearson,Carol Heycock,Clive Kelly,Martin Rynne,Vadivelu Saravanan,Jennifer Hamilton,Aamir Saeed,Robert J. Coughlan,John J. Carey,Ziad Farah,Wendy Matthews,Carolyn Bell,Sharon Petford,Lisa-Marie Tibbetts,Karen M J Douglas,Wendy Holden,Joanna M. Ledingham,Margaret Fletcher,Rachel Winfield,Zoe Price,Kirsten Mackay,Chris Dixon,Raymond Oppong,Sue Jowett,Elaine Nicholls,David G T Whitehurst,Susan L. Hill,Alison Hammond,Elaine M Hay,Krysia Dziedzic,Carina Righetti,Maximilan Lebmeier,Victoria Manning,Michael Hurley,David Scott,Ernest Choy,Lindsay Bearne,Elena Nikiphorou,Stephen Morris,D. James,Ernest Wong,Julie Long,Alex Fletcher,Simon Holmes,Peter Hockey,Mohsin Abbas,C. Chattopadhyay,Julia Flint,Mary Gayed,Karen Schreiber,Subha Arthanari,Mohamed Nisar,Munther A. Khamashta,Caroline Gordon,Ian Giles,Joanna C. Robson,Amit Kiran,Joe Maskell,Nigel Arden,Andrew Hutchings,Akan Emin,David Culliford,Bhaskar Dasgupta,William Hamilton,Raashid Luqmani,Hannah Jethwa,Dorota Rowczenio,H Trojer,Thirusha Russell,Jutta Loeffler,Philip N. Hawkins,Helen J. Lachmann,Inderjeet Verma,Ashit Syngle,Pawan Krishan,Nidhi Garg,Stephen P. McGowan,Dave T. Gerrard,Hector Chinoy,William E. Ollier,Robert G. Cooper,Janine A. Lamb,Lucia Taborda,Pedro Correia Azevedo,David A. Isenberg,Kirsten M. Leyland,Andrew Judge,Dave Hunter,D Hart,Muhammad K. Javaid,Mark H. Edwards,A E Litwic,Karen A. Jameson,Dorly Deeg,J Cushnaghan,Avan Aihie Sayer,Darshan Jagannath,Camille Parsons,Laura Stoppiello,Paul Mapp,Sadaf Ashraf,D. Wilson,R. Hill,Brigitte Scammell,Claire Y J Wenham,Patricia Shore,Richard Hodgson,Andrew J. Grainger,Jean Aaron,Lesley Hordon,Philip G. Conaghan,Yaron Bar-Ziv,Yiftah Beer,Yuvan Ran,Shaike Benedict,Nahum Halperin,Michael Drexler,Amit Mor,Ganit Segal,Amnon Lahad,Amir Haim,Udi Rath,David M. Morgensteren,Moshe Salai,Avi Elbaz,Vishwanath G. Vasishta,Emma Derrett-Smith,Rachel K. Hoyles,Korsa Khan,Amara Ezeonyeji,Gagandeep Takhar,Voon H Ong,Lorraine Loughrey,Lesley-Anne Bissell,Elizabeth M A Hensor,Giuseppina Abignano,Anthony C. Redmond,Francesco Del Galdo,Frances Hall,Anshuman P. Malaviya,Muhammad K Nisar,Sharon Baker,Anita Furlong,Alison Mitchell,Anna L. Godfrey,Michael Ruddlesden,Andreas V. Hadjinicolaou,Michael Hughes,Tonia L. Moore,Neil O'Leary,Andrew Tracey,Holly Ennis,Graham Dinsdale,Chris Roberts,Ariane L. Herrick,Christopher P. Denton,Loic Guillevin,Elke Hunsche,Daniel Rosenberg,Barbara Schwierin,Martin Scott,Thomas Krieg,Marina Anderson,Marco Matucci-Cerinic,Rebecca O. Alade,Shiwen Xu,Svetlana I. Nihtyanova,Kristina E N Clark,Frederick W.K. Tam,Robert J. Unwin,Richard Stratton,Benjamin E. Schreiber,Chong Seng Edwin Lim,Elisa Corsiero,Nurhan Sutcliffe,Hedda Wardemann,Costantino Pitzalis,Michele Bombardieri,Hasan Tahir,Simon Donnelly,Mandy Greenwood,Toby O. Smith,Vicky Easton,Holly Bacon,Emma Jerman,Kate Armon,Fiona Poland,Alex J. MacGregor,Désirée van der Heijde,Joachim Sieper,Dirk Elewaut,Aileen L. Pangan,Dianne Nguyen,Christoffel Badenhorst,Sandra Kirby,Douglas White,Andrew A. Harrison,José A. García,Simon Stebbings,James W. MacKay,Sharief Aboelmagd,Karl Gaffney,Atul Deodhar,Jurgen Braun,Michael Mack,B. Hsu,Tim Gathany,Chenglong Han,Robert D. Inman,Nicola Cooper-Moss,Jonathan Packham,Vicky Y. Strauss,Jane E. Freeston,Laura C. Coates,Jackie L Nam,Anna R. Moverley,Philip S. Helliwell,Richard J. Wakefield,Philip J. Mease,R. Fleischmann,J. Wollenhaupt,A. A. Deodhar,D. Kielar,F. Woltering,C. Stach,B. Hoepken,T. Arledge,D. Gladman,G. Coteur,A. Kavanaugh,O. Purcaru,Iain McInnes,Alice B Gottlieb,Lluis Puig,Proton Rahman,Christopher T. Ritchlin,Shu Li,Yuhua Wang,Alan M. Mendelsohn,Mittie Doyle,William Tillett,Deepak R Jadon,Gavin Shaddick,Charlotte Cavill,G. Robinson,Raj Sengupta,Eleanor Korendowych,Corinne S de Vries,Rebecca C. Thomas,Toshihide Shuto,Noemi Busquets-Pérez,Helena Marzo-Ortega,Dennis McGonagle,Gavin Richards,S. J. Bingham,P John Hamlin,Rebecca Adshead,Susannah Cambridge,Praema Suppiah,Mary P. Cullinan,Anita Nolan,W. M. Thompson,Hannah R. Mathieson,Sarah L. Mackie,Domini Bryer,Maria Krutikov,Leanne Gray,Ellen Bruce,Andrew Keat,William Innes,Ranjeet Pandit,Lesley Kay,S A LAPShINA,L. Myasoutova,Shandor Erdes,Dinny Wallis,Nicola Waldron,Iona Thorne,Claire Harris,Kanchan Vohra,Dinesh Khinchi,Ladbans Kaur,Alexis Jones,Nikki Harrison,Denise Harris,Timothy L. Jones,Jonathan Rees,Alexander N. Bennett,Shahid Fazal,Nicola Tugnet,Nick Barkham,Neil Basu,Andrew McClean,Lorraine Harper,Esther N. Amft,Neeraj Dhaun,Raashid A. Luqmani,Mark A. Little,David R. Jayne,Oliver Flossmann,John McLaren,Vinod Kumar,David M. Reid,Gary J. Macfarlane,Gareth Jones,Max Yates,Richard A. Watts,Laszlo Igali,Chetan Mukhtyar,Helen Doll,Stephen Yew,Ravi Suppiah,Peter Hoglund,David Jayne,Kerstin Westman,Win Win Maw,Pravin Patil,Mark R. Williams,Tochukwa Adizie,Dimitrios Christidis,Frances Borg,Alexander Robertson,Adam P. Croft,Stuart Smith,S. Carr,S. Youssouf,A. Salama,C. Pusey,L. Harper,M. Morgan +470 more
TL;DR: It is demonstrated that in vitro, SCF promotes proliferation and migration of fibroblasts and that its blockade using specific antibodies results in reduction in both these processes.
Journal Article
FOXp(3)(+) T-regulatory cell infiltrates in orofacial granulomatosis
Carlo Nunes,Michael Escudier,P. J. Shirlaw,Neil B. Rayment,Barry N. Hudspith,Gareth Parkes,Liljana Petrovska,Miranda Lomer,Jonathan Brostoff,C Chinyana,E Odell,Stephen Challacombe,Jeremy D. Sanderson,Jo Spencer +13 more