John L. Harwood

TL;DR: In this article, the authors proposed that membrane microheterogeneity is important for regulating heat-shock protein (HSP) response and that when particular membrane intercalating compounds are used to alter membrane properties, the simultaneous normalization of dysregulated expression of HSPs causes beneficial responses to disease states.

TL;DR: Observations emphasize the importance of membranes and their lipids in the heat shock response and provide a new perspective for guiding further studies into the mechanisms that mediate cellular and organismal responses to heat stress.

TL;DR: There is good evidence that olive oil is protective in cardiovascular diseases and cancer, and its mechanism of action may involve effects on blood lipids, but other mechanisms, including effects on immune function, endothelial function and the coagulation pathways remain possible and are discussed.

TL;DR: Results show that acetyl-CoA carboxylase is the major flux controlling enzyme for light-stimulated lipid synthesis in these tissues.

TL;DR: The classic heat shock (stress) response (HSR) was originally attributed to protein denaturation, but it is observed that a deregulated HSR is found in a large number of important diseases where more detailed knowledge of the molecular mechanisms involved may offer timely opportunities for clinical interventions and new, innovative drug treatments.