J
José A. Salas
Researcher at University of Oviedo
Publications - 188
Citations - 9577
José A. Salas is an academic researcher from University of Oviedo. The author has contributed to research in topics: Gene cluster & Streptomyces. The author has an hindex of 54, co-authored 181 publications receiving 8873 citations. Previous affiliations of José A. Salas include International Sleep Products Association.
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Journal ArticleDOI
Minimum Information about a Biosynthetic Gene cluster.
Marnix H. Medema,Marnix H. Medema,Renzo Kottmann,Pelin Yilmaz,Matthew Cummings,John B. Biggins,Kai Blin,Irene de Bruijn,Yit-Heng Chooi,Yit-Heng Chooi,Jan Claesen,R. Cameron Coates,Pablo Cruz-Morales,Srikanth Duddela,Stephanie Düsterhus,Daniel J. Edwards,David P. Fewer,Neha Garg,Christoph Geiger,Juan Pablo Gomez-Escribano,Anja Greule,Michalis Hadjithomas,Anthony S. Haines,Eric J. N. Helfrich,Matthew L. Hillwig,Keishi Ishida,Adam C. Jones,Carla S. Jones,Katrin Jungmann,Carsten Kegler,Hyun Uk Kim,Hyun Uk Kim,Peter Kötter,Daniel Krug,Joleen Masschelein,Alexey V. Melnik,Simone M. Mantovani,Emily A. Monroe,Marcus A. Moore,Nathan A. Moss,Hans-Wilhelm Nützmann,Guohui Pan,Amrita Pati,Daniel Petras,F. Jerry Reen,Federico Rosconi,Zhe Rui,Zhenhua Tian,Nicholas J. Tobias,Yuta Tsunematsu,Yuta Tsunematsu,Philipp Wiemann,Elizabeth E. Wyckoff,Xiaohui Yan,Grace Yim,Fengan Yu,Yunchang Xie,Bertrand Aigle,Alexander Kristian Apel,Carl J. Balibar,Emily P. Balskus,Francisco Barona-Gómez,Andreas Bechthold,Helge B. Bode,Rainer Borriss,Sean F. Brady,Axel A. Brakhage,Patrick Caffrey,Yi-Qiang Cheng,Jon Clardy,Russell J. Cox,Russell J. Cox,René De Mot,Stefano Donadio,Mohamed S. Donia,Wilfred A. van der Donk,Wilfred A. van der Donk,Pieter C. Dorrestein,Sean Doyle,Arnold J. M. Driessen,Monika Ehling-Schulz,K. D. Entian,Michael A. Fischbach,Lena Gerwick,William H. Gerwick,Harald Gross,Bertolt Gust,Christian Hertweck,Christian Hertweck,Monica Höfte,Susan E. Jensen,Jianhua Ju,Leonard Katz,Leonard Kaysser,Jonathan L. Klassen,Nancy P. Keller,Jan Kormanec,Oscar P. Kuipers,Tomohisa Kuzuyama,Nikos C. Kyrpides,Nikos C. Kyrpides,Hyung Jin Kwon,Sylvie Lautru,Rob Lavigne,Chia Y. Lee,Bai Linquan,Xinyu Liu,Wen Liu,Andriy Luzhetskyy,Taifo Mahmud,Yvonne Mast,Carmen Méndez,Mikko Metsä-Ketelä,Jason Micklefield,Douglas A. Mitchell,Bradley S. Moore,Leonilde M. Moreira,Rolf Müller,Brett A. Neilan,Markus Nett,Jens Nielsen,Jens Nielsen,Fergal O'Gara,Fergal O'Gara,Hideaki Oikawa,Anne Osbourn,Marcia S. Osburne,Bohdan Ostash,Shelley M. Payne,Jean-Luc Pernodet,Miroslav Petricek,Jörn Piel,Olivier Ploux,Jos M. Raaijmakers,José A. Salas,Esther K. Schmitt,Barry Scott,Ryan F. Seipke,Ben Shen,David H. Sherman,Kaarina Sivonen,Michael J. Smanski,Margherita Sosio,Evi Stegmann,Roderich D. Süssmuth,Kapil Tahlan,Christopher M. Thomas,Yi Tang,Andrew W. Truman,Muriel Viaud,Jonathan D. Walton,Christopher T. Walsh,Tilmann Weber,Gilles P. van Wezel,Barrie Wilkinson,Joanne M. Willey,Wolfgang Wohlleben,Gerard D. Wright,Nadine Ziemert,Changsheng Zhang,Sergey B. Zotchev,Rainer Breitling,Eriko Takano,Frank Oliver Glöckner,Frank Oliver Glöckner +164 more
TL;DR: This work proposes the Minimum Information about a Biosynthetic Gene cluster (MIBiG) data standard, to facilitate consistent and systematic deposition and retrieval of data on biosynthetic gene clusters.
Journal ArticleDOI
Indolocarbazole natural products: occurrence, biosynthesis, and biological activity
TL;DR: The indolocarbazole family of natural products, including the biosynthetically related bisindolylmaleimides, is reviewed, with an emphasis on the development of analogs that have entered clinical trials for its future use against cancer or other diseases.
Journal ArticleDOI
Antitumor Compounds from Marine Actinomycetes
TL;DR: Actinomycetes are the producers of a large number of natural products with different biological activities, including antitumor properties, and have attracted special attention in the last years for their ability to produce interesting pharmacological lead compounds.
Journal ArticleDOI
Improving production of bioactive secondary metabolites in actinomycetes by metabolic engineering.
TL;DR: In this review, the development of recombinant DNA technology has provided new tools for approaching yields improvement by means of genetic manipulation of biosynthetic pathways as applied to bioactive secondary metabolites produced by actinomycetes.
Journal ArticleDOI
Combinatorial biosynthesis of antitumor indolocarbazole compounds
Cesar Sanchez,Lili Zhu,Alfredo F. Braña,Aaroa Pérez Salas,Jürgen Rohr,Carmen Méndez,José A. Salas +6 more
TL;DR: A biological process based on combinatorial biosynthesis for the production of indolocarbazole compounds (or their precursors) in engineered microorganisms as a complementary approach to chemical synthesis is reported.