J
Jose C. Florez
Researcher at Harvard University
Publications - 414
Citations - 58686
Jose C. Florez is an academic researcher from Harvard University. The author has contributed to research in topics: Type 2 diabetes & Diabetes mellitus. The author has an hindex of 87, co-authored 357 publications receiving 50750 citations. Previous affiliations of Jose C. Florez include George Washington University & University of California, Davis.
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Journal ArticleDOI
Impact of Literacy and Numeracy on Motivation for Behavior Change After Diabetes Genetic Risk Testing
Jason L. Vassy,Kelsey O'Brien,Jessica L. Waxler,Elyse R. Park,Linda M. Delahanty,Jose C. Florez,James B. Meigs,Richard W. Grant +7 more
TL;DR: While patients reported that high-risk genetic results would motivate them to adopt healthy lifestyle changes, response to low-risk results varied by patient numeracy and literacy, and anticipated responses may not correlate with true behavior change.
Journal ArticleDOI
Pharmacogenetics in type 2 diabetes: potential implications for clinical practice
Chunmei Huang,Jose C. Florez +1 more
TL;DR: A contemporary overview of the pharmacogenetic field in its current state is offered, potential obstacles are identified, and future directions are highlighted to highlight future directions.
Journal ArticleDOI
Precision medicine in diabetes: an opportunity for clinical translation
TL;DR: How mounting data sets generated during the last decade to understand biological variability are now inspiring new venues to clarify diabetes nosology and ultimately translate findings into more effective prevention and treatment strategies is examined.
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Factors Affecting the Decline in Incidence of Diabetes in the Diabetes Prevention Program Outcomes Study (DPPOS)
Richard F. Hamman,Edward S. Horton,Elizabeth Barrett-Connor,George A. Bray,Costas A. Christophi,Jill P. Crandall,Jose C. Florez,Sarah E. Fowler,Ronald N. Goldberg,Steven E. Kahn,William C. Knowler,John M. Lachin,Mary Beth Murphy,Elizabeth M. Venditti +13 more
TL;DR: No combination of behavioral risk factors explained the lower DPPOS rates of diabetes progression in the placebo and metformin groups, whereas weight gain was the factor associated with higher rates of progress in the intensive lifestyle intervention group.
Journal ArticleDOI
Variation at the Melanocortin 4 Receptor Gene and Response to Weight-Loss Interventions in the Diabetes Prevention Program
Qing Pan,Linda M. Delahanty,Kathleen A. Jablonski,William C. Knowler,Steven E. Kahn,Jose C. Florez,Jose C. Florez,Paul W. Franks +7 more
TL;DR: To assess associations and genotype × treatment interactions for melanocortin 4 receptor (MC4R) locus variants and obesity‐related traits, a large number of variants and treatment interactions were identified.