Jose C. Florez

TL;DR: The Rare and Atypical Diabetes Network (RADIANT) as discussed by the authors performed a study of individuals and, if deemed informative, their family members with uncharacterized forms of diabetes, using genomic (whole-genome [WGS], RNA, and mitochondrial sequencing), phenotypic (vital signs, biometric measurements, questionnaires, and photography), metabolomics, and metabolic assessments.

TL;DR: In this paper , the authors used random survival forest and Lasso methods to identify the optimal miR predictors and the Cox proportional hazards to model time to T2D overall and within intervention arms.

TL;DR: In this article, a genome-wide association study was conducted to evaluate the genetic determinants of lipid traits in youth with Type 2 diabetes through a genome wide association study, which identified a novel association between a deletion on chromosome 3 (3:67817380_AT/A_Deletion:RP11-81N13.1) and triglyceride levels at genomewide level of significance with each risk allele increasing triglycerides by 20%.

TL;DR: The MAGIC study presented here presents a novel and scalable approach called “informed consent” that aims to provide real-time information about the protective and non-trivial effects of vaccination on heart disease and stroke in women.