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Jose C. Florez

Researcher at Harvard University

Publications -  414
Citations -  58686

Jose C. Florez is an academic researcher from Harvard University. The author has contributed to research in topics: Type 2 diabetes & Diabetes mellitus. The author has an hindex of 87, co-authored 357 publications receiving 50750 citations. Previous affiliations of Jose C. Florez include George Washington University & University of California, Davis.

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Whole Genome Sequence Association Analysis of Fasting Glucose and Fasting Insulin Levels in Diverse Cohorts from the NHLBI TOPMed Program

Daniel DiCorpo, +100 more
- 04 Jan 2021 - 
TL;DR: In this paper, a high-coverage whole-genome sequencing (WGS) analysis from fifteen cohorts in the NHLBI Trans-Omics for Precision Medicine (TOPMed) program was conducted.
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Effects of Initial Combinations of Gemigliptin Plus Metformin Compared with Glimepiride Plus Metformin on Gut Microbiota and Glucose Regulation in Obese Patients with Type 2 Diabetes: The INTESTINE Study

TL;DR: In this article , the effects of combinations of gemigliptin-metformin vs. glimepiride-meformin as initial therapies on gut microbiota and glucose homeostasis in drug-naïve patients with type 2 diabetes were investigated.
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223-OR: Identification of Novel Therapies for Monogenic Diabetes Using Connectivity Map (CMap)

TL;DR: Udler et al. as mentioned in this paper used CMap to identify 15 classes of medications with significantly enriched connectivity with HNF1A-knockdown by Mann-Whitney U-test (BH-adjusted P< 0.05).
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Proteomic analysis of cardiometabolic biomarkers and predictive modeling of severe outcomes in patients hospitalized with COVID-19

TL;DR: In this article , the authors performed proteomic analysis and developed predictive models for severe outcomes and used them to predict the outcomes of out-of-sample patients hospitalized with COVID-19 later in the surge (N = 194).