J
Jose C. Florez
Researcher at Harvard University
Publications - 414
Citations - 58686
Jose C. Florez is an academic researcher from Harvard University. The author has contributed to research in topics: Type 2 diabetes & Diabetes mellitus. The author has an hindex of 87, co-authored 357 publications receiving 50750 citations. Previous affiliations of Jose C. Florez include George Washington University & University of California, Davis.
Papers
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Journal ArticleDOI
It's not black and white: individualizing metformin treatment in type 2 diabetes.
TL;DR: African Americans were shown to be more responsive to metformin in terms of a change in HbA1C, even after adjusting for all relevant covariates, and this provocative finding, if confirmed, would define African Americans as more likely met formin responders when compared to European Americans.
Journal ArticleDOI
Case records of the Massachusetts General Hospital. Case 17-2013. A 56-year-old woman with poorly controlled diabetes mellitus and fatigue.
TL;DR: A 56-year-old woman with diabetes mellitus was admitted to this hospital because of hyperglycemia and chest pain.
Journal ArticleDOI
Genome-wide Association Study of Change in Fasting Glucose over time in 13,807 non-diabetic European Ancestry Individuals.
Ching-Ti Liu,Jordi Merino,Jordi Merino,Denis Rybin,Daniel DiCorpo,Kelly S. Benke,Jennifer L. Bragg-Gresham,Mickaël Canouil,Tanguy Corre,Tanguy Corre,Harald Grallert,Aaron Isaacs,Aaron Isaacs,Zoltán Kutalik,Zoltán Kutalik,Jari Lahti,Letizia Marullo,Carola Marzi,Laura J. Rasmussen-Torvik,Ghislain Rocheleau,Ghislain Rocheleau,Ghislain Rocheleau,Rico Rueedi,Rico Rueedi,Chiara Scapoli,Niek Verweij,Nicole Vogelzangs,Sara M. Willems,Loic Yengo,Stephan J. L. Bakker,John Beilby,John Beilby,Jennie Hui,Eero Kajantie,Martina Müller-Nurasyid,Wolfgang Rathmann,Beverley Balkau,Beverley Balkau,Sven Bergmann,Sven Bergmann,Sven Bergmann,Johan G. Eriksson,Johan G. Eriksson,Jose C. Florez,Jose C. Florez,Philippe Froguel,Philippe Froguel,Tamara B. Harris,Joseph Hung,Joseph Hung,Alan James,Alan James,Maryam Kavousi,Iva Miljkovic,Arthur W. Musk,Arthur W. Musk,Lyle J. Palmer,Annette Peters,Ronan Roussel,Ronan Roussel,Ronan Roussel,Pim van der Harst,Cornelia M. van Duijn,Peter Vollenweider,Inês Barroso,Inga Prokopenko,Inga Prokopenko,Josée Dupuis,Josée Dupuis,James B. Meigs,James B. Meigs,Nabila Bouatia-Naji,Nabila Bouatia-Naji +72 more
TL;DR: In this article, the authors conducted a genome-wide association study of longitudinal fasting glucose changes in up to 13,807 non-diabetic individuals of European descent from nine cohorts.
Book ChapterDOI
Chapter 14 – Diabetes
Miriam S. Udler,Jose C. Florez +1 more
TL;DR: This chapter will summarize the concept, history, and recent discoveries produced by genomic studies for T2D and glycemic traits, and highlighted possible targets for pharmacogenetics.
Journal ArticleDOI
The Type 2 Diabetes Knowledge Portal: An open access genetic resource dedicated to type 2 diabetes and related traits.
Maria C. Costanzo,Marcin von Grotthuss,Jeffrey Massung,Dongkeun Jang,Lizz Caulkins,Ryan Koesterer,Clint Gilbert,Ryan P. Welch,Parul Kudtarkar,Quy Hoang,Andrew P. Boughton,Preeti Singh,Ying Sun,Marc Duby,Annie Moriondo,Trang Nguyen,Patrick Smadbeck,Benjamin Alexander,Mackenzie E Brandes,Mary Carmichael,Peter Dornbos,Todd Green,Kenneth C. Huellas-Bruskiewicz,Yue Ji,Alexandria Kluge,Aoife McMahon,Josep M. Mercader,Oliver Ruebenacker,Sebanti Sengupta,Dylan Spalding,Daniel Taliun,Philip Smith,Melissa K. Thomas,Beena Akolkar,M. Julia Brosnan,Andriy Cherkas,Audrey Y. Chu,Eric B. Fauman,Caroline S. Fox,Tania Nayak Kamphaus,Melissa R. Miller,Lynette Qu Nguyen,Afshin Parsa,Dermot F. Reilly,Hartmut Ruetten,David Wholley,Norann A. Zaghloul,Gonçalo R. Abecasis,David Altshuler,Thomas M. Keane,Mark I. McCarthy,Kyle J. Gaulton,Jose C. Florez,Michael Boehnke,Noël P. Burtt,Nicholette Allred,Jennifer E. Below,Richard N. Bergman,Joline W.J. Beulens,John Blangero,Krister Bokvist,Erwin P. Bottinger,Donald W. Bowden,Christopher Brown,Kenneth T. Bruskiewicz,Ines dos Santos Cebola,John C. Chambers,Yii-Der Ida Chen,Chris P. Clark,Melina Claussnitzer,Nancy J. Cox,Marcel den Hoed,Duc Tuan Dong,Ravindranath Duggirala,Josée Dupuis,Petra J. M. Elders,Jesse M. Engreitz,Jorge Ferrer,Jason Flannick,Paul Flicek,Matthew Flickinger,Timothy M. Frayling,Kelly A. Frazer,Anna L. Gloyn,Craig L. Hanis,Robert Hanson,Andrew T. Hattersley,Hae Kyung Im,Sidra Iqbal,Suzanne B.R. Jacobs,Tadeusz Jordan,Tania Nayak Kamphaus,Fredrik Karpe,Seung K. Kim,Kasper Lage,Leslie A. Lange,Michael Lazar,Donna E. Lehman,Ching-Ti Liu,Ruth J. F. Loos,Ronald C.W. Ma,Patrick MacDonald,Matthew T. Maurano,Gil McVean,James B. Meigs,Braxton D. Mitchell,Karen L. Mohlke,Samuel Morabito,Claire Morgan,Shannon E. Mullican,Sharvari Narendra,Maggie C.Y. Ng,Colin N. A. Palmer,Stephen C. J. Parker,Antonio Parrado,Aaron C. Pawlyk,Ewan R. Pearson,Andrew S. Plump,Michael A. Province,Thomas Quertermous,Susan Redline,Bing Ren,Stephen S. Rich,J. Brent Richards,Jerome I. Rotter,Rany M. Salem,Maike Sander,Michael Sanders,Dharambir K. Sanghera,Laura J. Scott,David Siedzik,Xueling Sim,Robert Sladek,Kerrin S. Small,Peter Stein,Heather M. Stringham,Katalin Susztak,Leen M 't Hart,Kent D. Taylor,Jennifer A. Todd,Miriam S. Udler,Benjamin F. Voight,Andre Wan,Kaan Yuksel +143 more
TL;DR: The Type 2 Diabetes Knowledge Portal (T2DKP) as discussed by the authors is a public resource of genetic datasets and genomic annotations dedicated to type 2 diabetes and related traits, which can be used for access to complex disease genetic results.