J
Jose C. Florez
Researcher at Harvard University
Publications - 414
Citations - 58686
Jose C. Florez is an academic researcher from Harvard University. The author has contributed to research in topics: Type 2 diabetes & Diabetes mellitus. The author has an hindex of 87, co-authored 357 publications receiving 50750 citations. Previous affiliations of Jose C. Florez include George Washington University & University of California, Davis.
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Journal ArticleDOI
Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps.
Anubha Mahajan,Daniel Taliun,Matthias Thurner,Neil R. Robertson,Jason M. Torres,N. William Rayner,N. William Rayner,Anthony Payne,Valgerdur Steinthorsdottir,Robert A. Scott,Niels Grarup,James P. Cook,Ellen M. Schmidt,Matthias Wuttke,Chloé Sarnowski,Reedik Mägi,Jana Nano,Christian Gieger,Stella Trompet,Cécile Lecoeur,Michael Preuss,Bram P. Prins,Xiuqing Guo,Lawrence F. Bielak,Jennifer E. Below,Donald W. Bowden,John C. Chambers,Young-Jin Kim,Maggie C.Y. Ng,Lauren E. Petty,Xueling Sim,Weihua Zhang,Weihua Zhang,Amanda J. Bennett,Jette Bork-Jensen,Chad M. Brummett,Mickaël Canouil,Kai-Uwe Ec Kardt,Krista Fischer,Sharon L.R. Kardia,Florian Kronenberg,Kristi Läll,Ching-Ti Liu,Adam E. Locke,Jian'an Luan,Ioanna Ntalla,Vibe Nylander,Sebastian Schönherr,Claudia Schurmann,Loic Yengo,Erwin P. Bottinger,Ivan Brandslund,Cramer Christensen,George Dedoussis,Jose C. Florez,Ian Ford,Oscar H. Franco,Timothy M. Frayling,Vilmantas Giedraitis,Sophie Hackinger,Andrew T. Hattersley,Christian Herder,M. Arfan Ikram,Martin Ingelsson,Marit E. Jørgensen,Marit E. Jørgensen,Torben Jørgensen,Torben Jørgensen,Jennifer Kriebel,Johanna Kuusisto,Symen Ligthart,Cecilia M. Lindgren,Cecilia M. Lindgren,Allan Linneberg,Allan Linneberg,Valeriya Lyssenko,Valeriya Lyssenko,Vasiliki Mamakou,Thomas Meitinger,Karen L. Mohlke,Andrew D. Morris,Andrew D. Morris,Girish N. Nadkarni,James S. Pankow,Annette Peters,Naveed Sattar,Alena Stančáková,Konstantin Strauch,Kent D. Taylor,Barbara Thorand,Gudmar Thorleifsson,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,Jaakko Tuomilehto,Daniel R. Witte,Josée Dupuis,Patricia A. Peyser,Eleftheria Zeggini,Ruth J. F. Loos,Philippe Froguel,Philippe Froguel,Erik Ingelsson,Erik Ingelsson,Lars Lind,Leif Groop,Leif Groop,Markku Laakso,Francis S. Collins,J. Wouter Jukema,Colin N. A. Palmer,Harald Grallert,Andres Metspalu,Abbas Dehghan,Abbas Dehghan,Anna Köttgen,Gonçalo R. Abecasis,James B. Meigs,Jerome I. Rotter,Jonathan Marchini,Oluf Pedersen,Torben Hansen,Torben Hansen,Claudia Langenberg,Nicholas J. Wareham,Kari Stefansson,Kari Stefansson,Anna L. Gloyn,Andrew P. Morris,Andrew P. Morris,Andrew P. Morris,Michael Boehnke,Mark I. McCarthy +131 more
TL;DR: Combining 32 genome-wide association studies with high-density imputation provides a comprehensive view of the genetic contribution to type 2 diabetes in individuals of European ancestry with respect to locus discovery, causal-variant resolution, and mechanistic insight.
Journal ArticleDOI
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
Anubha Mahajan,Min Jin Go,Weihua Zhang,Jennifer E. Below,Kyle J. Gaulton,Teresa Ferreira,Momoko Horikoshi,Andrew D. Johnson,Maggie C.Y. Ng,Inga Prokopenko,Inga Prokopenko,Danish Saleheen,Xu Wang,Eleftheria Zeggini,Gonçalo R. Abecasis,Linda S. Adair,Peter Almgren,Mustafa Atalay,Tin Aung,Tin Aung,Damiano Baldassarre,Beverley Balkau,Beverley Balkau,Yuqian Bao,Anthony H. Barnett,Anthony H. Barnett,Inês Barroso,Inês Barroso,Inês Barroso,Abdul Basit,Latonya F. Been,John Beilby,John Beilby,Graeme I. Bell,Rafn Benediktsson,Richard N. Bergman,Bernhard OBoehm,Bernhard OBoehm,Eric Boerwinkle,Eric Boerwinkle,Lori L. Bonnycastle,Noël P. Burtt,Qiuyin Cai,Harry Campbell,Jason Carey,Stéphane Cauchi,Mark J. Caulfield,Juliana C.N. Chan,Li Ching Chang,Tien-Jyun Chang,Yi-Cheng Chang,Guillaume Charpentier,Chien-Hsiun Chen,Chien-Hsiun Chen,Han Chen,Yuan-Tsong Chen,Kee Seng Chia,Manickam Chidambaram,Peter S. Chines,Nam H. Cho,Young Min Cho,Lee-Ming Chuang,Francis S. Collins,Marilyn C. Cornelis,David Couper,Andrew Crenshaw,Rob M. van Dam,Rob M. van Dam,John Danesh,Debashish Das,Ulf de Faire,George Dedoussis,Panos Deloukas,Antigone S. Dimas,Christian Dina,Christian Dina,Alex S. F. Doney,Peter Donnelly,Mozhgan Dorkhan,Cornelia M. van Duijn,Josée Dupuis,Josée Dupuis,Sarah Edkins,Paul Elliott,Paul Elliott,Valur Emilsson,Raimund Erbel,Johan G. Eriksson,Jorge Escobedo,Tõnu Esko,Tõnu Esko,Elodie Eury,Jose C. Florez,Jose C. Florez,Pierre Fontanillas,Nita G. Forouhi,Tom Forsén,Caroline S. Fox,Caroline S. Fox,Ross M. Fraser,Timothy M. Frayling,Philippe Froguel,Philippe Froguel,Philippe M. Frossard,Yu-Tang Gao,Karl Gertow,Christian Gieger,Bruna Gigante,Harald Grallert,George B. Grant,Leif Groop,Christopher J. Groves,Elin Grundberg,Elin Grundberg,Elin Grundberg,Candace Guiducci,Anders Hamsten,Bok Ghee Han,Hara Kazuo,Neelam Hassanali,Andrew T. Hattersley,Caroline Hayward,Åsa K. Hedman,Christian Herder,Albert Hofman,Oddgeir L. Holmen,Kees Hovingh,Astradur B. Hreidarsson,Cheng Hu,Frank B. Hu,Jennie Hui,Jennie Hui,Steve E. Humphries,Sarah E. Hunt,David J. Hunter,Kristian Hveem,Zafar I. Hydrie,Hiroshi Ikegami,Thomas Illig,Erik Ingelsson,Erik Ingelsson,Muhammed Islam,Bo Isomaa,Anne U. Jackson,Tazeen H. Jafar,Alan James,Alan James,Weiping Jia,Karl-Heinz Jöckel,Anna Jonsson,Jeremy B M Jowett,Takashi Kadowaki,Hyun Min Kang,Stavroula Kanoni,Wen Hong L. Kao,Sekar Kathiresan,Sekar Kathiresan,Norihiro Kato,Prasad Katulanda,Prasad Katulanda,Sirkka Keinänen-Kiukaanniemi,Ann M. Kelly,Ann M. Kelly,Hassan Khan,Kay-Tee Khaw,Chiea Chuen Khor,Chiea Chuen Khor,Chiea Chuen Khor,Hyung Lae Kim,Sangsoo Kim,Young Jin Kim,Leena Kinnunen,Norman Klopp,Augustine Kong,Eeva Korpi-Hyövälti,Sudhir Kowlessur,Peter Kraft,Jasmina Kravic,Malene M. Kristensen,S. Krithika,Ashok Kumar,Jesús Kumate,Johanna Kuusisto,Soo Heon Kwak,Markku Laakso,Vasiliki Lagou,Timo A. Lakka,Claudia Langenberg,Cordelia Langford,Robert W. Lawrence,Karin Leander,Jen Mai Lee,Nanette R. Lee,Man Li,Xinzhong Li,Yun Li,Junbin Liang,Samuel Liju,Wei-Yen Lim,Lars Lind,Cecilia M. Lindgren,Cecilia M. Lindgren,Eero Lindholm,Ching-Ti Liu,Jianjun Liu,Stéphane Lobbens,Jirong Long,Ruth J. F. Loos,Ruth J. F. Loos,Wei Lu,Jian'an Luan,Valeriya Lyssenko,Ronald C. WMa,Shiro Maeda,Reedik Mägi,Satu Männistö,David R. Matthews,James B. Meigs,James B. Meigs,Olle Melander,Andres Metspalu,Julia Meyer,Ghazala Mirza,Evelin Mihailov,Susanne Moebus,Viswanathan Mohan,Viswanathan Mohan,Karen L. Mohlke,Andrew D. Morris,Thomas WMühleisen,Martina Müller-Nurasyid,Martina Müller-Nurasyid,Bill Musk,Bill Musk,Jiro Nakamura,Eitaro Nakashima,Pau Navarro,Peng Keat Ng,Alexandra C. Nica,Peter M. Nilsson,Inger Njølstad,Markus M. Nöthen,Keizo Ohnaka,Twee Hee Ong,Katharine R. Owen,Colin N. A. Palmer,James S. Pankow,Kyong Soo Park,Melissa Parkin,Sonali Pechlivanis,Nancy L. Pedersen,Leena Peltonen,John R. B. Perry,John R. B. Perry,Annette Peters,Janani Pinidiyapathirage,Carl G. P. Platou,Simon C. Potter,Jackie F. Price,Lu Qi,Venkatesan Radha,Loukianos S. Rallidis,Asif Rasheed,Wolfgang Rathmann,Rainer Rauramaa,Soumya Raychaudhuri,N. William Rayner,Simon D. Rees,Simon D. Rees,Emil Rehnberg,Samuli Ripatti,Samuli Ripatti,Samuli Ripatti,Neil Robertson,Michael Roden,Elizabeth J. Rossin,Elizabeth J. Rossin,Elizabeth J. Rossin,Igor Rudan,Denis Rybin,Timo Saaristo,Veikko Salomaa,Juha Saltevo,Maria Samuel,Dharambir KSanghera,Jouko Saramies,James Scott,Laura J. Scott,Robert A. Scott,Ayellet V. Segrè,Ayellet V. Segrè,Joban Sehmi,Joban Sehmi,Bengt Sennblad,Nabi Shah,Sonia Shah,A. Samad Shera,Xiao-Ou Shu,Alan R. Shuldiner,Gunnar Sigurosson,Eric J.G. Sijbrands,Angela Silveira,Xueling Sim,Xueling Sim,Suthesh Sivapalaratnam,Kerrin S. Small,Kerrin S. Small,Wing-Yee So,Alena Stančáková,Kari Stefansson,Kari Stefansson,Gerald Steinbach,Valgerdur Steinthorsdottir,Kathleen Stirrups,Rona J. Strawbridge,Heather M. Stringham,Qi Sun,Chen Suo,Ann-Christine Syvänen,Ryoichi Takayanagi,Fumihiko Takeuchi,Wan Ting Tay,Tanya M. Teslovich,Barbara Thorand,Gudmar Thorleifsson,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,Emmi Tikkanen,Emmi Tikkanen,Joseph Trakalo,Elena Tremoli,Mieke D. Trip,Fuu Jen Tsai,Tiinamaija Tuomi,Jaakko Tuomilehto,Jaakko Tuomilehto,Jaakko Tuomilehto,André G. Uitterlinden,Adan Valladares-Salgado,Sailaja Vedantam,Sailaja Vedantam,Fabrizio Veglia,Benjamin F. Voight,Benjamin F. Voight,Congrong Wang,Nicholas J. Wareham,Roman Wennauer,Ananda R. Wickremasinghe,Tom Wilsgaard,James F. Wilson,S Wiltshire,Wendy Winckler,Tien Yin Wong,Tien Yin Wong,Tien Yin Wong,Andrew R. Wood,Jer-Yuarn Wu,Jer-Yuarn Wu,Ying Wu,Ken Yamamoto,Toshimasa Yamauchi,Mingyu Yang,Loic Yengo,Mitsuhiro Yokota,Robin Young,Delilah Zabaneh,Fan Zhang,Rong Zhang,Wei Zheng,Paul Zimmet,David Altshuler,David Altshuler,Donald W. Bowden,Donald W. Bowden,Yoon Shin Cho,Nancy J. Cox,Miguel Cruz,Craig L. Hanis,Jaspal S. Kooner,Jaspal S. Kooner,Jaspal S. Kooner,Jong-Young Lee,Mark Seielstad,Mark Seielstad,Mark Seielstad,Yik Ying Teo,Yik Ying Teo,Michael Boehnke,Esteban J. Parra,John C. Chambers,John C. Chambers,John C. Chambers,E. Shyong Tai,Mark I. McCarthy,Andrew P. Morris,Andrew P. Morris +395 more
TL;DR: In this paper, the authors aggregated published meta-analyses of genome-wide association studies (GWAS), including 26,488 cases and 83,964 controls of European, east Asian, south Asian and Mexican and Mexican American ancestry.
Journal ArticleDOI
The genetic architecture of type 2 diabetes
Christian Fuchsberger,Christian Fuchsberger,Jason Flannick,Jason Flannick,Tanya M. Teslovich,Anubha Mahajan,Vineeta Agarwala,Vineeta Agarwala,Kyle J. Gaulton,Clement Ma,Pierre Fontanillas,Loukas Moutsianas,Davis J. McCarthy,Manuel A. Rivas,John R. B. Perry,Xueling Sim,Thomas W. Blackwell,Neil Robertson,N. William Rayner,N. William Rayner,Pablo Cingolani,Adam E. Locke,Juan Fernandez Tajes,Heather M. Highland,Josée Dupuis,Josée Dupuis,Peter S. Chines,Cecilia M. Lindgren,Cecilia M. Lindgren,Christopher Hartl,Anne U. Jackson,Han Chen,Han Chen,Jeroen R. Huyghe,Martijn van de Bunt,Richard D. Pearson,Ashok Kumar,Ashok Kumar,Martina Müller-Nurasyid,Niels Grarup,Heather M. Stringham,Eric R. Gamazon,Jae-Hoon Lee,Yi Chen,Robert A. Scott,Jennifer E. Below,Peng Chen,Jinyan Huang,Min Jin Go,Michael L. Stitzel,Dorota Pasko,Stephen C. J. Parker,Tibor V. Varga,Todd Green,Nicola L. Beer,Aaron G. Day-Williams,Teresa Ferreira,Tasha E. Fingerlin,Momoko Horikoshi,Cheng Hu,Iksoo Huh,Mohammad Kamran Ikram,Mohammad Kamran Ikram,Bong-Jo Kim,Yongkang Kim,Young-Jin Kim,Min-Seok Kwon,Juyoung Lee,Selyeong Lee,Keng-Han Lin,Taylor J. Maxwell,Yoshihiko Nagai,Xu Wang,Ryan P. Welch,Joon Yoon,Weihua Zhang,Weihua Zhang,Nir Barzilai,Benjamin F. Voight,Bok-Ghee Han,Christopher P. Jenkinson,Christopher P. Jenkinson,Teemu Kuulasmaa,Johanna Kuusisto,Alisa K. Manning,Maggie C.Y. Ng,Nicholette D. Palmer,Beverley Balkau,Alena Stančáková,Hanna E. Abboud,Heiner Boeing,Vilmantas Giedraitis,Dorairaj Prabhakaran,Omri Gottesman,James Scott,Jason Carey,Phoenix Kwan,George B. Grant,Joshua D. Smith,Benjamin M. Neale,Benjamin M. Neale,Shaun Purcell,Shaun Purcell,Shaun Purcell,Adam S. Butterworth,Joanna M. M. Howson,Heung Man Lee,Yingchang Lu,Soo Heon Kwak,Wei Zhao,John Danesh,John Danesh,Vincent K. L. Lam,Kyong Soo Park,Danish Saleheen,Wing-Yee So,Claudia H. T. Tam,Uzma Afzal,David Aguilar,Rector Arya,Tin Aung,Tin Aung,Edmund Chan,Carmen Navarro,Ching-Yu Cheng,Ching-Yu Cheng,Domenico Palli,Adolfo Correa,Joanne E. Curran,Denis Rybin,Vidya S. Farook,Sharon P. Fowler,Barry I. Freedman,Michael Griswold,Daniel E. Hale,Pamela J. Hicks,Chiea Chuen Khor,Satish Kumar,Benjamin Lehne,Dorothée Thuillier,Wei-Yen Lim,Jianjun Liu,Jianjun Liu,Yvonne T. van der Schouw,Marie Loh,Marie Loh,Marie Loh,Solomon K. Musani,Sobha Puppala,William R. Scott,Loic Yengo,Sian-Tsung Tan,Sian-Tsung Tan,Herman A. Taylor,Farook Thameem,Gregory P. Wilson,Tien Yin Wong,Tien Yin Wong,Pål R. Njølstad,Jonathan C. Levy,Massimo Mangino,Lori L. Bonnycastle,Thomas Schwarzmayr,João Fadista,Gabriela L. Surdulescu,Christian Herder,Christopher J. Groves,Thomas Wieland,Jette Bork-Jensen,Ivan Brandslund,Cramer Christensen,Heikki A. Koistinen,Heikki A. Koistinen,Heikki A. Koistinen,Alex S. F. Doney,Leena Kinnunen,Tõnu Esko,Tõnu Esko,Tõnu Esko,Andrew Farmer,Liisa Hakaste,Dylan Hodgkiss,Jasmina Kravic,Valeriya Lyssenko,Mette Hollensted,Marit E. Jørgensen,Torben Jørgensen,Torben Jørgensen,Claes Ladenvall,Johanne Marie Justesen,Annemari Käräjämäki,Jennifer Kriebel,Wolfgang Rathmann,Lars Lannfelt,Torsten Lauritzen,Narisu Narisu,Allan Linneberg,Olle Melander,Lili Milani,Matt Neville,Marju Orho-Melander,Lu Qi,Qibin Qi,Qibin Qi,Michael Roden,Olov Rolandsson,Amy J. Swift,Anders Rosengren,Kathleen Stirrups,Andrew R. Wood,Evelin Mihailov,Christine Blancher,Mauricio O. Carneiro,Jared Maguire,Ryan Poplin,Khalid Shakir,Timothy Fennell,Mark A. DePristo,Martin Hrabé de Angelis,Panos Deloukas,Panos Deloukas,Anette P. Gjesing,Goo Jun,Goo Jun,Peter M. Nilsson,Jacquelyn Murphy,Robert C. Onofrio,Barbara Thorand,Torben Hansen,Torben Hansen,Christa Meisinger,Frank B. Hu,Bo Isomaa,Fredrik Karpe,Liming Liang,Annette Peters,Cornelia Huth,Stephen O'Rahilly,Colin N. A. Palmer,Oluf Pedersen,Rainer Rauramaa,Jaakko Tuomilehto,Veikko Salomaa,Richard M. Watanabe,Ann-Christine Syvänen,Richard N. Bergman,Dwaipayan Bharadwaj,Erwin P. Bottinger,Yoon Shin Cho,Giriraj R. Chandak,Juliana C.N. Chan,Kee Seng Chia,Mark J. Daly,Shah Ebrahim,Claudia Langenberg,Paul Elliott,Kathleen A. Jablonski,Donna M. Lehman,Weiping Jia,Ronald C.W. Ma,Toni I. Pollin,Manjinder S. Sandhu,Manjinder S. Sandhu,Nikhil Tandon,Philippe Froguel,Philippe Froguel,Inês Barroso,Inês Barroso,Yik Ying Teo,Eleftheria Zeggini,Ruth J. F. Loos,Kerrin S. Small,Janina S. Ried,Ralph A. DeFronzo,Harald Grallert,Benjamin Glaser,Andres Metspalu,Nicholas J. Wareham,Mark Walker,Eric Banks,Christian Gieger,Erik Ingelsson,Erik Ingelsson,Hae Kyung Im,Thomas Illig,Paul W. Franks,Paul W. Franks,Paul W. Franks,Gemma Buck,Joseph Trakalo,David Buck,Inga Prokopenko,Inga Prokopenko,Reedik Mägi,Lars Lind,Yossi Farjoun,Katharine R. Owen,Anna L. Gloyn,Konstantin Strauch,Tiinamaija Tuomi,Jaspal S. Kooner,Jaspal S. Kooner,Jong-Young Lee,Taesung Park,Peter Donnelly,Andrew D. Morris,Andrew D. Morris,Andrew T. Hattersley,Donald W. Bowden,Francis S. Collins,Gil Atzmon,Gil Atzmon,John C. Chambers,John C. Chambers,Tim D. Spector,Markku Laakso,Tim M. Strom,Graeme I. Bell,John Blangero,Ravindranath Duggirala,E. Shyong Tai,Gilean McVean,Craig L. Hanis,James G. Wilson,Mark Seielstad,Mark Seielstad,Timothy M. Frayling,James B. Meigs,Nancy J. Cox,Robert Sladek,Eric S. Lander,Stacey Gabriel,Noël P. Burtt,Karen L. Mohlke,Thomas Meitinger,Leif Groop,Leif Groop,Gonçalo R. Abecasis,Jose C. Florez,Jose C. Florez,Laura J. Scott,Andrew P. Morris,Andrew P. Morris,Andrew P. Morris,Hyun Min Kang,Michael Boehnke,David Altshuler,David Altshuler,David Altshuler,Mark I. McCarthy +349 more
TL;DR: In this paper, the authors performed whole-genome sequencing in 2,657 European individuals with and without diabetes, and exome sequencing for 12,940 individuals from five ancestry groups.
Journal ArticleDOI
TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program.
Jose C. Florez,Kathleen A. Jablonski,Nick Bayley,Toni I. Pollin,Paul I.W. de Bakker,Alan R. Shuldiner,William C. Knowler,David M. Nathan,David Altshuler +8 more
TL;DR: The risk-conferring genotypes in TCF7L2 are associated with impaired beta-cell function but not with insulin resistance, and seem to be associated with an increased risk of diabetes among persons with impaired glucose tolerance.
Journal ArticleDOI
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.
Alisa K. Manning,Alisa K. Manning,Alisa K. Manning,Robert A. Scott,Jonna L. Grimsby,Nabila Bouatia-Naji,Nabila Bouatia-Naji,Han Chen,Denis Rybin,Ching-Ti Liu,Lawrence F. Bielak,Inga Prokopenko,Najaf Amin,Daniel R. Barnes,Gemma Cadby,Gemma Cadby,Jouke-Jan Hottenga,Erik Ingelsson,Anne U. Jackson,Toby Johnson,Stavroula Kanoni,Claes Ladenvall,Vasiliki Lagou,Jari Lahti,Cécile Lecoeur,Cécile Lecoeur,Yongmei Liu,María Teresa Martínez-Larrad,May E. Montasser,Pau Navarro,John R. B. Perry,John R. B. Perry,John R. B. Perry,Laura J. Rasmussen-Torvik,Perttu Salo,Naveed Sattar,Dmitry Shungin,Dmitry Shungin,Rona J. Strawbridge,Toshiko Tanaka,Cornelia M. van Duijn,Ping An,Mariza de Andrade,Jeanette S. Andrews,Thor Aspelund,Mustafa Atalay,Yurii S. Aulchenko,Beverley Balkau,Stefania Bandinelli,Jacques S. Beckmann,John Beilby,Claire Bellis,Richard N. Bergman,John Blangero,Mladen Boban,Michael Boehnke,Eric Boerwinkle,Lori L. Bonnycastle,Dorret I. Boomsma,Ingrid B. Borecki,Yvonne Böttcher,Claude Bouchard,Eric J. Brunner,Danijela Budimir,Harry Campbell,Olga D. Carlson,Peter S. Chines,Robert Clarke,Francis S. Collins,Arturo Corbató-Anchuelo,David Couper,Ulf de Faire,George Dedoussis,Panos Deloukas,Maria Dimitriou,Josephine M. Egan,Gudny Eiriksdottir,Michael R. Erdos,Johan G. Eriksson,Elodie Eury,Elodie Eury,Luigi Ferrucci,Ian Ford,Nita G. Forouhi,Caroline S. Fox,Caroline S. Fox,Maria Grazia Franzosi,Paul W. Franks,Timothy M. Frayling,Philippe Froguel,Pilar Galan,Eco J. C. de Geus,Bruna Gigante,Nicole L. Glazer,Anuj Goel,Leif Groop,Vilmundur Gudnason,Göran Hallmans,Anders Hamsten,Ola Hansson,Tamara B. Harris,Caroline Hayward,Simon Heath,Serge Hercberg,Andrew A. Hicks,Aroon D. Hingorani,Albert Hofman,Jennie Hui,Joseph Hung,Marjo-Riitta Järvelin,Marjo-Riitta Järvelin,Min A. Jhun,Paul C. D. Johnson,J. Wouter Jukema,Antti Jula,Wen Hong L. Kao,Jaakko Kaprio,Jaakko Kaprio,Sharon L.R. Kardia,Sirkka Keinänen-Kiukaanniemi,Mika Kivimäki,Ivana Kolcic,Peter Kovacs,Meena Kumari,Johanna Kuusisto,Kirsten Ohm Kyvik,Markku Laakso,Timo A. Lakka,Lars Lannfelt,G. Mark Lathrop,Lenore J. Launer,Karin Leander,Guo Li,Lars Lind,Jaana Lindström,Stéphane Lobbens,Stéphane Lobbens,Ruth J. F. Loos,Jian'an Luan,Valeriya Lyssenko,Reedik Mägi,Reedik Mägi,Patrik K. E. Magnusson,Michael Marmot,Pierre Meneton,Karen L. Mohlke,Vincent Mooser,Mario A. Morken,Iva Miljkovic,Narisu Narisu,Jeffrey R. O'Connell,Ken K. Ong,Ben A. Oostra,Lyle J. Palmer,Lyle J. Palmer,Aarno Palotie,Aarno Palotie,Aarno Palotie,James S. Pankow,John F. Peden,Nancy L. Pedersen,Marina Pehlić,Leena Peltonen,Leena Peltonen,Brenda W.J.H. Penninx,Brenda W.J.H. Penninx,Brenda W.J.H. Penninx,Marijana Peričić,Markus Perola,Louis Pérusse,Patricia A. Peyser,Ozren Polasek,Peter P. Pramstaller,Michael A. Province,Katri Räikkönen,Rainer Rauramaa,Emil Rehnberg,Kenneth Rice,Jerome I. Rotter,Igor Rudan,Igor Rudan,Aimo Ruokonen,Timo Saaristo,Maria Sabater-Lleal,Veikko Salomaa,David B. Savage,Richa Saxena,Richa Saxena,Peter Schwarz,Udo Seedorf,Bengt Sennblad,Manuel Serrano-Ríos,Alan R. Shuldiner,Eric J.G. Sijbrands,David S. Siscovick,Johannes H. Smit,Kerrin S. Small,Nicholas L. Smith,Nicholas L. Smith,Nicholas L. Smith,Albert V. Smith,Alena Stančáková,Kathleen Stirrups,Michael Stumvoll,Yan V. Sun,Amy J. Swift,Anke Tönjes,Jaakko Tuomilehto,Stella Trompet,André G. Uitterlinden,Matti Uusitupa,Max Vikström,Veronique Vitart,Marie-Claude Vohl,Benjamin F. Voight,Peter Vollenweider,Gerard Waeber,Dawn M. Waterworth,Hugh Watkins,Hugh Watkins,Eleanor Wheeler,Elisabeth Widen,Sarah H. Wild,Sara M. Willems,Gonneke Willemsen,James F. Wilson,Jacqueline C.M. Witteman,Alan F. Wright,Hanieh Yaghootkar,Diana Zelenika,Tatijana Zemunik,Lina Zgaga,Lina Zgaga,Nicholas J. Wareham,Mark I. McCarthy,Inês Barroso,Inês Barroso,Richard M. Watanabe,Jose C. Florez,Jose C. Florez,José Dupuis,José Dupuis,James B. Meigs,Claudia Langenberg +243 more
TL;DR: Six previously unknown loci associated with fasting insulin at P < 5 × 10−8 in combined discovery and follow-up analyses of 52 studies comprising up to 96,496 non-diabetic individuals are presented.