L
Ludovic Vallier
Researcher at University of Cambridge
Publications - 199
Citations - 17332
Ludovic Vallier is an academic researcher from University of Cambridge. The author has contributed to research in topics: Induced pluripotent stem cell & Embryonic stem cell. The author has an hindex of 55, co-authored 180 publications receiving 14503 citations. Previous affiliations of Ludovic Vallier include Wellcome Trust & Columbia University.
Papers
More filters
Journal ArticleDOI
Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis.
Rudi Alberts,Elisabeth M.G. de Vries,Elizabeth C. Goode,Elizabeth C. Goode,Xiaojun Jiang,F. Sampaziotis,Krista Rombouts,Katrin Böttcher,Trine Folseraas,Tobias J. Weismüller,Andrew Mason,Weiwei Wang,Graeme J.M. Alexander,Domenico Alvaro,Annika Bergquist,Niklas K. Björkström,Ulrich Beuers,Einar Bjornsson,Kirsten Muri Boberg,Kirsten Muri Boberg,Christopher L. Bowlus,Maria Consiglia Bragazzi,Marco Carbone,Olivier Chazouillères,Angela M. Cheung,Georgios N. Dalekos,John E. Eaton,Bertus Eksteen,David Ellinghaus,Martti Färkkilä,Eleonora A. M. Festen,Annarosa Floreani,I. Franceschet,Daniel Gotthardt,Gideon M. Hirschfield,Bart van Hoek,Kristian Holm,Simon Hohenester,Johannes R. Hov,Floris Imhann,Pietro Invernizzi,Brian D. Juran,Henrike Lenzen,Wolfgang Lieb,Jimmy Z. Liu,Hanns-Ulrich Marschall,Marco Marzioni,Espen Melum,Piotr Milkiewicz,Tobias Müller,Albert Parés,Christian Rupp,Christian Rust,Richard Sandford,Christoph Schramm,Stefan Schreiber,Erik Schrumpf,Mark S. Silverberg,Brijesh Srivastava,Martina Sterneck,Andreas Teufel,Ludovic Vallier,Ludovic Vallier,Joanne Verheij,Arnau Vich Vila,A. Boudewijn de Vries,Kalliopi Zachou,Roger W. Chapman,Michael P. Manns,Massimo Pinzani,Simon M. Rushbrook,Konstantinos N. Lazaridis,Andre Franke,Carl A. Anderson,Tom H. Karlsen,Cyriel Y. Ponsioen,Rinse K. Weersma +76 more
TL;DR: A genome-wide significant signal is identified and expression of the candidate gene RSPO3 is demonstrated in key liver-resident effector cells, such as human and murine cholangiocytes and human hepatic stellate cells, which warrants further assessments of the role of this potential key PSC modifier gene.
Book ChapterDOI
The serpinopathies studying serpin polymerization in vivo.
James A. Irving,Ugo I. Ekeowa,Didier Belorgey,Imran Haq,Bibek Gooptu,Elena Miranda,Juan Pérez,Benoit D. Roussel,Adriana Ordóñez,Lucy E. Dalton,Sally E. Thomas,Stefan J. Marciniak,Helen Parfrey,Edwin R. Chilvers,Jeffrey Teckman,Sam Alam,Ravi Mahadeva,Sheikh Tamir Rashid,Ludovic Vallier,David A. Lomas +19 more
TL;DR: The biochemical techniques, monoclonal antibodies, cell biology, animal models, and stem cell technology that are useful to characterize the serpin polymers that form in vivo are described.
Journal ArticleDOI
Mouse pluripotent stem cells at a glance.
TL;DR: Embryonic stem cells (ESCs) are derived from the inner cell mass of an embryo at the blastocyst stage and are characterised by the ability to proliferate indefinitely (or self-renew) in vitro while maintaining pluripotency, i.e. the capacity to differentiate into germ cells and a broad range of cell types.
Journal ArticleDOI
Tissue-Engineering the Intestine: The Trials before the Trials
Hans Clevers,Ryan K. Conder,Vivian S. W. Li,Matthias P. Lutolf,Ludovic Vallier,Sarah Chan,Tracy C. Grikscheit,Kim B. Jensen,Paolo De Coppi,Paolo De Coppi +9 more
TL;DR: The INTENS Consortium discuss experimental considerations and challenges for generating a tissue-engineered intestine for the treatment of short bowel syndrome, taking into account cell source, scaffold choice, and design strategy for achieving proper assembly and function.
Journal ArticleDOI
International coordination of large-scale human induced pluripotent stem cell initiatives: Wellcome Trust and ISSCR workshops white paper.
Filipa A.C. Soares,Michael Sheldon,Mahendra Rao,Christine L. Mummery,Ludovic Vallier,Ludovic Vallier +5 more
TL;DR: The purpose was to discuss strategies for making thousands of hiPSC lines widely available with as few restrictions as possible while retaining financial viability and donor privacy.