T
Tulio Guadalupe
Researcher at Max Planck Society
Publications - 37
Citations - 3658
Tulio Guadalupe is an academic researcher from Max Planck Society. The author has contributed to research in topics: Genome-wide association study & Brain asymmetry. The author has an hindex of 22, co-authored 37 publications receiving 3040 citations. Previous affiliations of Tulio Guadalupe include Radboud University Nijmegen & Erasmus University Rotterdam.
Papers
More filters
Journal ArticleDOI
Common genetic variants influence human subcortical brain structures.
Derrek P. Hibar,Jason L. Stein,Jason L. Stein,Miguel E. Rentería,Alejandro Arias-Vasquez,Sylvane Desrivières,Neda Jahanshad,Roberto Toro,Roberto Toro,Katharina Wittfeld,Katharina Wittfeld,Lucija Abramovic,Micael Andersson,Benjamin S. Aribisala,Benjamin S. Aribisala,Nicola J. Armstrong,Nicola J. Armstrong,Manon Bernard,Marc M. Bohlken,Marco P. Boks,Janita Bralten,Andrew A. Brown,M. Mallar Chakravarty,M. Mallar Chakravarty,Qiang Chen,Christopher R.K. Ching,Christopher R.K. Ching,Gabriel Cuellar-Partida,Anouk den Braber,Sudheer Giddaluru,Aaron Goldman,Oliver Grimm,Tulio Guadalupe,Johanna Hass,Girma Woldehawariat,Avram J. Holmes,Avram J. Holmes,Martine Hoogman,Deborah Janowitz,Tianye Jia,Sungeun Kim,Marieke Klein,Bernd Kraemer,Phil Lee,Phil Lee,Loes M. Olde Loohuis,Michelle Luciano,Christine Macare,Karen A. Mather,Manuel Mattheisen,Manuel Mattheisen,Yuri Milaneschi,Kwangsik Nho,Martina Papmeyer,Adaikalavan Ramasamy,Adaikalavan Ramasamy,Shannon L. Risacher,Roberto Roiz-Santiañez,Emma J. Rose,Alireza Salami,Alireza Salami,Philipp G. Sämann,Lianne Schmaal,Andrew J. Schork,Jean Shin,Lachlan T. Strike,Lachlan T. Strike,Alexander Teumer,Marjolein M.J. van Donkelaar,Kristel R. van Eijk,Raymond K. Walters,Raymond K. Walters,Lars T. Westlye,Christopher D. Whelan,Anderson M. Winkler,Anderson M. Winkler,Marcel P. Zwiers,Saud Alhusaini,Saud Alhusaini,Lavinia Athanasiu,Stefan Ehrlich,Stefan Ehrlich,Marina Hakobjan,Cecilie B. Hartberg,Unn K. Haukvik,Angelien Heister,D. Hoehn,Dalia Kasperaviciute,Dalia Kasperaviciute,David C. Liewald,Lorna M. Lopez,Remco R. R. Makkinje,Mar Matarin,Marlies Naber,D. Reese McKay,Margaret Needham,Allison C. Nugent,Benno Pütz,Natalie A. Royle,Li Shen,Emma Sprooten,Emma Sprooten,Daniah Trabzuni,Daniah Trabzuni,Saskia S. L. van der Marel,Kimm J. E. van Hulzen,Esther Walton,Christiane Wolf,Laura Almasy,Laura Almasy,David Ames,David Ames,Sampath Arepalli,Amelia A. Assareh,Mark E. Bastin,Henry Brodaty,Kazima B. Bulayeva,Melanie A. Carless,Sven Cichon,Sven Cichon,Aiden Corvin,Joanne E. Curran,Michael Czisch,Greig I. de Zubicaray,Allissa Dillman,Ravi Duggirala,Thomas D. Dyer,Thomas D. Dyer,Susanne Erk,Iryna O. Fedko,Luigi Ferrucci,Tatiana Foroud,Peter T. Fox,Peter T. Fox,Masaki Fukunaga,J. Raphael Gibbs,J. Raphael Gibbs,Harald H H Göring,Robert C. Green,Sebastian Guelfi,Narelle K. Hansell,Catharina A. Hartman,Katrin Hegenscheid,Andreas Heinz,Dena G. Hernandez,Dena G. Hernandez,Dirk J. Heslenfeld,Pieter J. Hoekstra,Florian Holsboer,Georg Homuth,Jouke-Jan Hottenga,Masashi Ikeda,Clifford R. Jack,Mark Jenkinson,Robert Johnson,Ryota Kanai,Ryota Kanai,Maria Keil,Jack W. Kent,Peter Kochunov,John B.J. Kwok,John B.J. Kwok,Stephen M. Lawrie,Xinmin Liu,Xinmin Liu,Dan L. Longo,Katie L. McMahon,Eva M. Meisenzahl,Ingrid Melle,Sebastian Mohnke,Grant W. Montgomery,Jeanette C. Mostert,Thomas W. Mühleisen,Mike A. Nalls,Thomas E. Nichols,Thomas E. Nichols,Lars Nilsson,Markus M. Nöthen,Kazutaka Ohi,Rene L. Olvera,Rocío Pérez-Iglesias,G. Bruce Pike,Steven G. Potkin,Ivar Reinvang,Simone Reppermund,Marcella Rietschel,Nina Romanczuk-Seiferth,Glenn D. Rosen,Dan Rujescu,Knut Schnell,Peter R. Schofield,Peter R. Schofield,Colin Smith,Vidar M. Steen,Jessika E. Sussmann,Anbupalam Thalamuthu,Arthur W. Toga,Bryan J. Traynor,Juan C. Troncoso,Jessica A. Turner,Maria C. Valdés Hernández,Dennis van 't Ent,Marcel P. van der Brug,Nic J.A. van der Wee,Marie-José van Tol,Dick J. Veltman,Thomas H. Wassink,Eric Westman,Ronald H. Zielke,Alan B. Zonderman,David G. Ashbrook,Reinmar Hager,Lu Lu,Lu Lu,Francis J. McMahon,Derek W. Morris,Derek W. Morris,Robert W. Williams,Han G. Brunner,Han G. Brunner,Randy L. Buckner,Jan K. Buitelaar,Wiepke Cahn,Vince D. Calhoun,Vince D. Calhoun,Gianpiero L. Cavalleri,Benedicto Crespo-Facorro,Anders M. Dale,Gareth E. Davies,Norman Delanty,Norman Delanty,Chantal Depondt,Srdjan Djurovic,Wayne C. Drevets,Wayne C. Drevets,Thomas Espeseth,Randy L. Gollub,Beng-Choon Ho,Wolfgang Hoffmann,Wolfgang Hoffmann,Norbert Hosten,René S. Kahn,Stephanie Le Hellard,Andreas Meyer-Lindenberg,Bertram Müller-Myhsok,Bertram Müller-Myhsok,Matthias Nauck,Lars Nyberg,Massimo Pandolfo,Brenda W.J.H. Penninx,Joshua L. Roffman,Sanjay M. Sisodiya,Jordan W. Smoller,Jordan W. Smoller,Hans van Bokhoven,Neeltje E.M. van Haren,Henry Völzke,Henrik Walter,Michael W. Weiner,Wei Wen,Tonya White,Ingrid Agartz,Ingrid Agartz,Ole A. Andreassen,John Blangero,John Blangero,Dorret I. Boomsma,Rachel M. Brouwer,Dara M. Cannon,Dara M. Cannon,Mark R. Cookson,Eco J. C. de Geus,Ian J. Deary,Gary Donohoe,Gary Donohoe,Guillén Fernández,Simon E. Fisher,Simon E. Fisher,Clyde Francks,Clyde Francks,David C. Glahn,Hans J. Grabe,Oliver Gruber,Oliver Gruber,John Hardy,Ryota Hashimoto,Hilleke E. Hulshoff Pol,Erik G. Jönsson,Erik G. Jönsson,Iwona Kłoszewska,Simon Lovestone,Simon Lovestone,Venkata S. Mattay,Patrizia Mecocci,Colm McDonald,Andrew M. McIntosh,Roel A. Ophoff,Roel A. Ophoff,Tomáš Paus,Zdenka Pausova,Mina Ryten,Mina Ryten,Perminder S. Sachdev,Andrew J. Saykin,Andrew J. Saykin,Andrew Simmons,Andrew B. Singleton,Hilkka Soininen,Joanna M. Wardlaw,Michael E. Weale,Daniel R. Weinberger,Hieab H.H. Adams,Lenore J. Launer,Stephan Seiler,Reinhold Schmidt,Ganesh Chauhan,Claudia L. Satizabal,Claudia L. Satizabal,James T. Becker,Lisa R. Yanek,Sven J. van der Lee,Maritza Ebling,Bruce Fischl,Bruce Fischl,W. T. Longstreth,Douglas N. Greve,Helena Schmidt,Paul A. Nyquist,Louis N. Vinke,Cornelia M. van Duijn,Luting Xue,Bernard Mazoyer,Joshua C. Bis,Vilmundur Gudnason,Sudha Seshadri,Sudha Seshadri,M. Arfan Ikram,Nicholas G. Martin,Margaret J. Wright,Margaret J. Wright,Gunter Schumann,Barbara Franke,Barbara Franke,Paul M. Thompson,Sarah E. Medland +344 more
TL;DR: In this paper, the authors conduct genome-wide association studies of the volumes of seven subcortical regions and the intracranial volume derived from magnetic resonance images of 30,717 individuals from 50 cohorts.
Journal ArticleDOI
The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data
Paul M. Thompson,Jason L. Stein,Sarah E. Medland,Derrek P. Hibar,Alejandro Arias Vasquez,Miguel E. Rentería,Roberto Toro,Neda Jahanshad,Gunter Schumann,Barbara Franke,Margaret J. Wright,Nicholas G. Martin,Ingrid Agartz,Ingrid Agartz,Martin Alda,Saud Alhusaini,Saud Alhusaini,Laura Almasy,Jorge R. C. Almeida,Jorge R. C. Almeida,Jorge R. C. Almeida,Kathryn I. Alpert,Nancy C. Andreasen,Ole A. Andreassen,Liana G. Apostolova,Katja Appel,Nicola J. Armstrong,Benjamin S. Aribisala,Mark E. Bastin,Michael Bauer,Carrie E. Bearden,Ørjan Bergmann,Elisabeth B. Binder,John Blangero,HJ Bockholt,Erlend Bøen,Catherine Bois,Dorret I. Boomsma,Tom Booth,Ian Bowman,Janita Bralten,Rachel M. Brouwer,Han G. Brunner,David G. Brohawn,Randy L. Buckner,Jan K. Buitelaar,Kazima B. Bulayeva,Juan R. Bustillo,Vince D. Calhoun,Vince D. Calhoun,Dara M. Cannon,Rita M. Cantor,Melanie A. Carless,Xavier Caseras,Gianpiero L. Cavalleri,M. Mallar Chakravarty,Kiki D. Chang,Christopher R.K. Ching,Andrea Christoforou,Andrea Christoforou,Sven Cichon,Sven Cichon,Vincent P. Clark,Patricia J. Conrod,Patricia J. Conrod,Giovanni Coppola,Benedicto Crespo-Facorro,Joanne E. Curran,Michael Czisch,Ian J. Deary,Eco J. C. de Geus,Anouk den Braber,G. Delvecchio,Chantal Depondt,Lieuwe de Haan,Lieuwe de Haan,Greig I. de Zubicaray,Danai Dima,Rali Dimitrova,Srdjan Djurovic,Hong-Wei Dong,Gary Donohoe,Gary Donohoe,Ravindranath Duggirala,Thomas D. Dyer,Stefan Ehrlich,Stefan Ehrlich,Carl Johan Ekman,Torbjørn Elvsåshagen,Louise Emsell,Susanne Erk,Thomas Espeseth,Jesen Fagerness,Scott C. Fears,Iryna O. Fedko,Guillén Fernández,Simon E. Fisher,Simon E. Fisher,Tatiana Foroud,Peter T. Fox,Clyde Francks,Clyde Francks,Sophia Frangou,Eva Maria Frey,Thomas Frodl,Thomas Frodl,Vincent Frouin,Hugh Garavan,Sudheer Giddaluru,David C. Glahn,Beata R. Godlewska,Rita Z. Goldstein,Randy L. Gollub,Hans J. Grabe,Oliver Grimm,Oliver Gruber,Tulio Guadalupe,Raquel E. Gur,Ruben C. Gur,Ruben C. Gur,Harald H H Göring,Saskia P. Hagenaars,Tomas Hajek,Geoffrey B. Hall,Jeremy Hall,Jeremy Hall,John Hardy,Catharina A. Hartman,Johanna Hass,Sean N. Hatton,Unn K. Haukvik,K Hegenscheid,Andreas Heinz,Ian B. Hickie,Beng-Choon Ho,D. Hoehn,Pieter J. Hoekstra,Marisa O. Hollinshead,Avram J. Holmes,Georg Homuth,Martine Hoogman,L. Elliot Hong,Norbert Hosten,Jouke-Jan Hottenga,Hilleke E. Hulshoff Pol,Kristy S. Hwang,Clifford R. Jack,Mark Jenkinson,Caroline Johnston,Caroline Johnston,Erik G. Jönsson,René S. Kahn,Dalia Kasperaviciute,Sinead Kelly,Sungeun Kim,Peter Kochunov,Laura Koenders,Laura Koenders,Bernd Krämer,John B.J. Kwok,John B.J. Kwok,Jim Lagopoulos,Gonzalo Laje,Mikael Landén,Mikael Landén,Bennett A. Landman,John Lauriello,Stephen M. Lawrie,Phil Lee,Phil Lee,Stephanie Le Hellard,Stephanie Le Hellard,Herve Lemaitre,Cassandra D. Leonardo,Chiang shan Li,Benny Liberg,David C. Liewald,Xinmin Liu,Xinmin Liu,Lorna M. Lopez,Eva Loth,Anbarasu Lourdusamy,Michelle Luciano,Fabio Macciardi,Fabio Macciardi,Marise W. J. Machielsen,Marise W. J. Machielsen,Glenda MacQueen,Ulrik Fredrik Malt,René C.W. Mandl,Dara S. Manoach,Jean-Luc Martinot,Mar Matarin,Karen A. Mather,Manuel Mattheisen,Manuel Mattheisen,Morten Mattingsdal,Andreas Meyer-Lindenberg,Colm McDonald,Andrew M. McIntosh,Francis J. McMahon,Katie L. McMahon,Eva M. Meisenzahl,Ingrid Melle,Yuri Milaneschi,Yuri Milaneschi,Sebastian Mohnke,Grant W. Montgomery,Derek W. Morris,Eric K. Moses,Eric K. Moses,Bryon A. Mueller,Susana Muñoz Maniega,Thomas W. Mühleisen,Bertram Müller-Myhsok,Benson Mwangi,Matthias Nauck,Kwangsik Nho,Thomas E. Nichols,Lars-Göran Nilsson,Lars-Göran Nilsson,Allison C. Nugent,Lars Nyberg,Rene L. Olvera,Jaap Oosterlaan,Roel A. Ophoff,Roel A. Ophoff,Massimo Pandolfo,Melina Papalampropoulou-Tsiridou,Martina Papmeyer,Tomáš Paus,Zdenka Pausova,Godfrey D. Pearlson,Godfrey D. Pearlson,Brenda W.J.H. Penninx,Charles P. Peterson,Andrea Pfennig,Mary L. Phillips,G. Bruce Pike,Jean-Baptiste Poline,Steven G. Potkin,Benno Pütz,Adaikalavan Ramasamy,Adaikalavan Ramasamy,Jerod M. Rasmussen,Marcella Rietschel,Mark Rijpkema,Shannon L. Risacher,Joshua L. Roffman,Roberto Roiz-Santiañez,Nina Romanczuk-Seiferth,Emma J. Rose,Natalie A. Royle,Dan Rujescu,Mina Ryten,Mina Ryten,Perminder S. Sachdev,Alireza Salami,Alireza Salami,Theodore D. Satterthwaite,Jonathan Savitz,Jonathan Savitz,Andrew J. Saykin,Cathy Scanlon,Lianne Schmaal,Hugo G. Schnack,Andrew J. Schork,S. Charles Schulz,Remmelt R. Schür,Larry J. Seidman,Li Shen,Jody M. Shoemaker,Andrew Simmons,Andrew Simmons,Sanjay M. Sisodiya,Colin Smith,Jordan W. Smoller,Jordan W. Smoller,Jair C. Soares,Scott R. Sponheim,Scott R. Sponheim,Emma Sprooten,John M. Starr,Vidar M. Steen,Vidar M. Steen,Stephen M. Strakowski,Lachlan T. Strike,Jessika E. Sussmann,Philipp G. Sämann,Alexander Teumer,Arthur W. Toga,Diana Tordesillas-Gutiérrez,Daniah Trabzuni,Daniah Trabzuni,Sarah Trost,Jessica A. Turner,Jessica A. Turner,Martijn P. van den Heuvel,Nic J.A. van der Wee,Kristel R. van Eijk,Theo G.M. van Erp,Neeltje E.M. van Haren,Dennis van 't Ent,Marie-José van Tol,Maria C. Valdés Hernández,Dick J. Veltman,Amelia Versace,Henry Völzke,Robert Walker,Henrik Walter,Henrik Walter,Lei Wang,Joanna M. Wardlaw,Michael E. Weale,Michael W. Weiner,Wei Wen,Lars T. Westlye,Heather C. Whalley,Christopher D. Whelan,Tonya White,Anderson M. Winkler,Anderson M. Winkler,Katharina Wittfeld,Girma Woldehawariat,Christiane Wolf,David Zilles,Marcel P. Zwiers,Anbupalam Thalamuthu,Peter R. Schofield,Peter R. Schofield,Nelson B. Freimer,Natalia Lawrence,Wayne C. Drevets +332 more
TL;DR: The ENIGMA Consortium has detected factors that affect the brain that no individual site could detect on its own, and that require larger numbers of subjects than any individual neuroimaging study has currently collected.
Journal ArticleDOI
Novel genetic loci associated with hippocampal volume
Derrek P. Hibar,Hieab H.H. Adams,Neda Jahanshad,Ganesh Chauhan,Jason L. Stein,Jason L. Stein,Edith Hofer,Miguel E. Rentería,Joshua C. Bis,Alejandro Arias-Vasquez,M. Kamran Ikram,Sylvane Desrivières,Meike W. Vernooij,Lucija Abramovic,Saud Alhusaini,Saud Alhusaini,Najaf Amin,Micael Andersson,Konstantinos Arfanakis,Konstantinos Arfanakis,Benjamin S. Aribisala,Benjamin S. Aribisala,Nicola J. Armstrong,Nicola J. Armstrong,Lavinia Athanasiu,Tomas Axelsson,Ashley Beecham,Alexa S. Beiser,Alexa S. Beiser,Manon Bernard,Susan H. Blanton,Marc M. Bohlken,Marco P. Boks,Janita Bralten,Adam M. Brickman,Owen Carmichael,M. Mallar Chakravarty,M. Mallar Chakravarty,Qiang Chen,Christopher R.K. Ching,Christopher R.K. Ching,Vincent Chouraki,Vincent Chouraki,Vincent Chouraki,Gabriel Cuellar-Partida,Fabrice Crivello,Anouk den Braber,Nhat Trung Doan,Stefan Ehrlich,Stefan Ehrlich,Sudheer Giddaluru,Aaron Goldman,Rebecca F. Gottesman,Oliver Grimm,Michael Griswold,Tulio Guadalupe,Boris A. Gutman,Johanna Hass,Unn K. Haukvik,D. Hoehn,Avram J. Holmes,Avram J. Holmes,Martine Hoogman,Deborah Janowitz,Tianye Jia,Kjetil Nordbø Jørgensen,Nazanin Karbalai,Dalia Kasperaviciute,Dalia Kasperaviciute,Sungeun Kim,Marieke Klein,Bernd Kraemer,Phil Lee,Phil Lee,David C. Liewald,Lorna M. Lopez,Michelle Luciano,Christine Macare,Andre F. Marquand,Mar Matarin,Mar Matarin,Karen A. Mather,Manuel Mattheisen,Manuel Mattheisen,David R. McKay,Yuri Milaneschi,Susana Muñoz Maniega,Kwangsik Nho,Allison C. Nugent,Paul A. Nyquist,Loes M. Olde Loohuis,Jaap Oosterlaan,Martina Papmeyer,Martina Papmeyer,Lukas Pirpamer,Benno Pütz,Adaikalavan Ramasamy,Adaikalavan Ramasamy,Adaikalavan Ramasamy,Jennifer S. Richards,Shannon L. Risacher,Roberto Roiz-Santiañez,Nanda Rommelse,Stefan Ropele,Emma J. Rose,Natalie A. Royle,Tatjana Rundek,Philipp G. Sämann,Arvin Saremi,Claudia L. Satizabal,Claudia L. Satizabal,Lianne Schmaal,Lianne Schmaal,Andrew J. Schork,Li Shen,Jean Shin,Elena Shumskaya,Albert V. Smith,Emma Sprooten,Emma Sprooten,Lachlan T. Strike,Lachlan T. Strike,Alexander Teumer,Diana Tordesillas-Gutiérrez,Roberto Toro,Daniah Trabzuni,Daniah Trabzuni,Stella Trompet,Dhananjay Vaidya,Jeroen van der Grond,Sven J. van der Lee,Dennis van der Meer,Marjolein M.J. van Donkelaar,Kristel R. van Eijk,Theo G.M. van Erp,Daan van Rooij,Daan van Rooij,Esther Walton,Esther Walton,Lars T. Westlye,Lars T. Westlye,Christopher D. Whelan,Christopher D. Whelan,Beverly G. Windham,Anderson M. Winkler,Anderson M. Winkler,Katharina Wittfeld,Katharina Wittfeld,Girma Woldehawariat,Christiane Wolf,Thomas Wolfers,Lisa R. Yanek,Jingyun Yang,Jingyun Yang,Alex P. Zijdenbos,Marcel P. Zwiers,Ingrid Agartz,Ingrid Agartz,Laura Almasy,Laura Almasy,Laura Almasy,D. Ames,D. Ames,Philippe Amouyel,Ole A. Andreassen,Sampath Arepalli,Amelia A. Assareh,Sandra Barral,Mark E. Bastin,Diane M. Becker,James T. Becker,David A. Bennett,David A. Bennett,John Blangero,Hans van Bokhoven,Dorret I. Boomsma,Henry Brodaty,Henry Brodaty,Rachel M. Brouwer,Han G. Brunner,Han G. Brunner,Randy L. Buckner,Randy L. Buckner,Jan K. Buitelaar,Kazima B. Bulayeva,Wiepke Cahn,Vince D. Calhoun,Dara M. Cannon,Dara M. Cannon,Gianpiero L. Cavalleri,Ching-Yu Cheng,Ching-Yu Cheng,Ching-Yu Cheng,Sven Cichon,Sven Cichon,Sven Cichon,M. R. Cookson,Aiden Corvin,Benedicto Crespo-Facorro,Joanne E. Curran,Michael Czisch,Anders M. Dale,Gareth E. Davies,Anton J. M. de Craen,Eco J. C. de Geus,Philip L. De Jager,Philip L. De Jager,Philip L. De Jager,Greig I. de Zubicaray,Ian J. Deary,Stéphanie Debette,Stéphanie Debette,Stéphanie Debette,Charles C. DeCarli,Norman Delanty,Norman Delanty,Chantal Depondt,Anita L. DeStefano,Anita L. DeStefano,Allissa Dillman,Srdjan Djurovic,Srdjan Djurovic,G. Donohoe,G. Donohoe,Wayne C. Drevets,Wayne C. Drevets,Ravi Duggirala,Thomas D. Dyer,Christian Enzinger,Susanne Erk,Thomas Espeseth,Thomas Espeseth,Iryna O. Fedko,Guillén Fernández,Luigi Ferrucci,Simon E. Fisher,Simon E. Fisher,Debra A. Fleischman,Debra A. Fleischman,Ian Ford,Myriam Fornage,Tatiana Foroud,Tatiana Foroud,Peter T. Fox,Clyde Francks,Clyde Francks,Masaki Fukunaga,J. Raphael Gibbs,J. Raphael Gibbs,David C. Glahn,Randy L. Gollub,Harald H.H. Göring,Robert C. Green,Robert C. Green,Oliver Gruber,Vilmundur Gudnason,Sebastian Guelfi,Asta Håberg,Asta Håberg,Narelle K. Hansell,Narelle K. Hansell,John Hardy,Catharina A. Hartman,Ryota Hashimoto,Ryota Hashimoto,K Hegenscheid,Andreas Heinz,Stephanie Le Hellard,Dena G. Hernandez,Dena G. Hernandez,Dirk J. Heslenfeld,Beng-Choon Ho,Pieter J. Hoekstra,Wolfgang Hoffmann,Wolfgang Hoffmann,Albert Hofman,Florian Holsboer,Florian Holsboer,Georg Homuth,Norbert Hosten,Jouke-Jan Hottenga,Matthew J. Huentelman,Hilleke E. Hulshoff Pol,Masashi Ikeda,Clifford R. Jack,Mark Jenkinson,Robert Johnson,Erik G. Jönsson,Erik G. Jönsson,J. Wouter Jukema,René S. Kahn,Ryota Kanai,Ryota Kanai,Ryota Kanai,I. Kloszewska,David S. Knopman,Peter Kochunov,John B.J. Kwok,John B.J. Kwok,Stephen M. Lawrie,Herve Lemaitre,Xinmin Liu,Xinmin Liu,Dan L. Longo,Oscar L. Lopez,Simon Lovestone,Simon Lovestone,Oliver Martinez,Jean-Luc Martinot,Venkata S. Mattay,Venkata S. Mattay,C. McDonald,Andrew M. McIntosh,Francis J. McMahon,Katie L. McMahon,P. Mecocci,Ingrid Melle,Andreas Meyer-Lindenberg,Sebastian Mohnke,Grant W. Montgomery,D. Morris,Thomas H. Mosley,Thomas W. Mühleisen,Thomas W. Mühleisen,Bertram Müller-Myhsok,Bertram Müller-Myhsok,Michael A. Nalls,Matthias Nauck,Matthias Nauck,Thomas E. Nichols,Wiro J. Niessen,Wiro J. Niessen,Markus M. Nöthen,Markus M. Nöthen,Lars Nyberg,Kazutaka Ohi,Rene L. Olvera,Roel A. Ophoff,Roel A. Ophoff,Massimo Pandolfo,Tomáš Paus,Tomáš Paus,Zdenka Pausova,Zdenka Pausova,Brenda W.J.H. Penninx,G. Bruce Pike,G. Bruce Pike,Steven G. Potkin,Bruce M. Psaty,Simone Reppermund,Simone Reppermund,Marcella Rietschel,Joshua L. Roffman,Nina Romanczuk-Seiferth,Jerome I. Rotter,Mina Ryten,Mina Ryten,Ralph L. Sacco,Ralph L. Sacco,Perminder S. Sachdev,Perminder S. Sachdev,Andrew J. Saykin,Andrew J. Saykin,Reinhold Schmidt,Helena Schmidt,Peter R. Schofield,Peter R. Schofield,Sigurdur Sigursson,Andrew Simmons,Andrew Simmons,Andrew Singleton,Sanjay M. Sisodiya,Colin Smith,Jordan W. Smoller,Jordan W. Smoller,Hilkka Soininen,Hilkka Soininen,Vidar M. Steen,David J. Stott,Jessika E. Sussmann,Anbupalam Thalamuthu,Arthur W. Toga,Bryan J. Traynor,Juan C. Troncoso,Magda Tsolaki,Christophe Tzourio,Christophe Tzourio,Andre G. Uitterlinden,Andre G. Uitterlinden,Maria del C. Valdés Hernández,Marcel Van Der Brug,Aad van der Lugt,Nic J.A. van der Wee,Neeltje E.M. van Haren,Dennis van 't Ent,Marie-José van Tol,Badri N. Vardarajan,Bruno Vellas,Dick J. Veltman,Henry Völzke,Henrik Walter,Joanna M. Wardlaw,Thomas H. Wassink,Michael E. Weale,Daniel R. Weinberger,Michael Weiner,Wei Wen,Wei Wen,Eric Westman,Tonya White,Tonya White,Tien Yin Wong,Tien Yin Wong,Tien Yin Wong,Clinton B. Wright,Clinton B. Wright,Ronald H. Zielke,Alan B. Zonderman,Nicholas G. Martin,Cornelia M. van Duijn,Margaret J. Wright,Margaret J. Wright,William T. Longstreth,Gunter Schumann,Hans J. Grabe,Barbara Franke,Lenore J. Launer,Sarah E. Medland,Sudha Seshadri,Sudha Seshadri,Paul M. Thompson,M. Arfan Ikram,M. Arfan Ikram +432 more
TL;DR: It is shown that genetic variants associated with decreased hippocampal volume are also associated with increased risk for Alzheimer's disease (rg=−0.155), and these findings suggest novel biological pathways through which human genetic variation influences hippocampus volume and risk for neuropsychiatric illness.
Journal ArticleDOI
Mapping cortical brain asymmetry in 17,141 healthy individuals worldwide via the ENIGMA consortium
Xiangzhen Kong,Samuel R. Mathias,Tulio Guadalupe,David C. Glahn,Barbara Franke,Fabrice Crivello,Nathalie Tzourio-Mazoyer,Simon E. Fisher,Paul M. Thompson,Clyde Francks,Clyde Francks +10 more
TL;DR: The structural asymmetries identified and their variabilities and heritability provide a reference resource for future studies on the genetic basis of brain asymmetry and altered laterality in cognitive, neurological, and psychiatric disorders.
Journal ArticleDOI
Novel genetic loci underlying human intracranial volume identified through genome-wide association
Hieab H.H. Adams,Derrek P. Hibar,Vincent Chouraki,Vincent Chouraki,Vincent Chouraki,Jason L. Stein,Jason L. Stein,Paul A. Nyquist,Miguel E. Rentería,Stella Trompet,Alejandro Arias-Vasquez,Sudha Seshadri,Sudha Seshadri,Sylvane Desrivières,Ashley Beecham,Neda Jahanshad,Katharina Wittfeld,Katharina Wittfeld,Sven J. van der Lee,Lucija Abramovic,Saud Alhusaini,Saud Alhusaini,Najaf Amin,Micael Andersson,Konstantinos Arfanakis,Konstantinos Arfanakis,Benjamin S. Aribisala,Benjamin S. Aribisala,Nicola J. Armstrong,Nicola J. Armstrong,Lavinia Athanasiu,Tomas Axelsson,Alexa S. Beiser,Alexa S. Beiser,Manon Bernard,Joshua C. Bis,Laura M. E. Blanken,Susan H. Blanton,Marc M. Bohlken,Marco P. Boks,Janita Bralten,Adam M. Brickman,Owen Carmichael,M. Mallar Chakravarty,M. Mallar Chakravarty,Ganesh Chauhan,Qiang Chen,Christopher R.K. Ching,Christopher R.K. Ching,Gabriel Cuellar-Partida,Anouk den Braber,Nhat Trung Doan,Stefan Ehrlich,Stefan Ehrlich,Irina Filippi,Irina Filippi,Tian Ge,Tian Ge,Sudheer Giddaluru,Aaron L. Goldman,Rebecca F. Gottesman,Corina U. Greven,Corina U. Greven,Oliver Grimm,Michael Griswold,Tulio Guadalupe,Tulio Guadalupe,Johanna Hass,Unn K. Haukvik,Saima Hilal,Edith Hofer,D. Hoehn,Avram J. Holmes,Avram J. Holmes,Martine Hoogman,Deborah Janowitz,Tianye Jia,Dalia Kasperaviciute,Dalia Kasperaviciute,Sungeun Kim,Marieke Klein,Bernd Kraemer,Phil H. Lee,Phil H. Lee,Jiemin Liao,David C. Liewald,Lorna M. Lopez,Michelle Luciano,Christine Macare,Andre F. Marquand,Mar Matarin,Mar Matarin,Karen A. Mather,Manuel Mattheisen,Manuel Mattheisen,Bernard Mazoyer,David Reese McKay,Rebekah McWhirter,Yuri Milaneschi,Nazanin Mirza-Schreiber,Ryan L. Muetzel,Susana Muñoz Maniega,Kwangsik Nho,Allison C. Nugent,Loes M. Olde Loohuis,Jaap Oosterlaan,Martina Papmeyer,Martina Papmeyer,Irene Pappa,Lukas Pirpamer,Sara Pudas,Benno Pütz,Kumar B. Rajan,Adaikalavan Ramasamy,Adaikalavan Ramasamy,Adaikalavan Ramasamy,Jennifer S. Richards,Shannon L. Risacher,Roberto Roiz-Santiañez,Nanda Rommelse,Emma J. Rose,Natalie A. Royle,Tatjana Rundek,Philipp G. Sämann,Claudia L. Satizabal,Lianne Schmaal,Andrew J. Schork,Andrew J. Schork,Li Shen,Jean Shin,Elena Shumskaya,Albert V. Smith,Emma Sprooten,Lachlan T. Strike,Alexander Teumer,Alexander Teumer,Russell Thomson,Diana Tordesillas-Gutiérrez,Roberto Toro,Daniah Trabzuni,Dhananjay Vaidya,Dhananjay Vaidya,Jeroen van der Grond,Dennis van der Meer,Marjolein M. J. Van Donkelaar,Kristel R. van Eijk,Theo G.M. van Erp,Daan van Rooij,Esther Walton,Esther Walton,Lars T. Westlye,Christopher D. Whelan,Beverly G Windham,Beverly G Windham,Anderson M. Winkler,Girma Woldehawariat,Girma Woldehawariat,Girma Woldehawariat,Christiane Wolf,Thomas Wolfers,Bing Xu,Lisa R. Yanek,Jingyun Yang,Alex P. Zijdenbos,Marcel P. Zwiers,Ingrid Agartz,Ingrid Agartz,Neelum T. Aggarwal,Laura Almasy,Laura Almasy,David Ames,David Ames,Philippe Amouyel,Ole A. Andreassen,Sampath Arepalli,Amelia A. Assareh,Sandra Barral,Mark E. Bastin,Diane M. Becker,James T. Becker,David A. Bennett,John Blangero,Hans van Bokhoven,Dorret I. Boomsma,Henry Brodaty,Rachel M. Brouwer,Han G. Brunner,Han G. Brunner,Randy L. Buckner,Jan K. Buitelaar,Kazima B. Bulayeva,Wiepke Cahn,Vince D. Calhoun,Vince D. Calhoun,Dara M. Cannon,Dara M. Cannon,Gianpiero L. Cavalleri,Christopher Chen,Ching-Yu Cheng,Ching-Yu Cheng,Sven Cichon,Sven Cichon,Mark R. Cookson,Aiden Corvin,Benedicto Crespo-Facorro,Joanne E. Curran,Michael Czisch,Anders M. Dale,Gareth E. Davies,Gareth E. Davies,Gareth E. Davies,Eco J. C. de Geus,Philip L. De Jager,Philip L. De Jager,Philip L. De Jager,Greig I. Zubicaray,Norman Delanty,Norman Delanty,Chantal Depondt,Anita L. DeStefano,Anita L. DeStefano,Allissa Dillman,Srdjan Djurovic,Srdjan Djurovic,Gary Donohoe,Gary Donohoe,Wayne C. Drevets,Wayne C. Drevets,Ravi Duggirala,Thomas D. Dyer,Susanne Erk,Thomas Espeseth,Denis A. Evans,Iryna O. Fedko,Guillén Fernández,Luigi Ferrucci,Simon E. Fisher,Simon E. Fisher,Debra A. Fleischman,Debra A. Fleischman,Debra A. Fleischman,Ian Ford,Tatiana Foroud,Tatiana Foroud,Peter T. Fox,Clyde Francks,Clyde Francks,Masaki Fukunaga,J. Raphael Gibbs,J. Raphael Gibbs,David C. Glahn,Randy L. Gollub,Harald H H Göring,Hans J. Grabe,Robert C. Green,Robert C. Green,Oliver Gruber,Vilmundur Gudnason,Sebastian Guelfi,Narelle K. Hansell,Narelle K. Hansell,John Hardy,Catharina A. Hartman,Ryota Hashimoto,Ryota Hashimoto,Katrin Hegenscheid,Andreas Heinz,Stephanie Le Hellard,Dena G. Hernandez,Dena G. Hernandez,Dena G. Hernandez,Dirk J. Heslenfeld,Beng-Choon Ho,Pieter J. Hoekstra,Wolfgang Hoffmann,Wolfgang Hoffmann,Albert Hofman,Florian Holsboer,Florian Holsboer,Georg Homuth,Norbert Hosten,Jouke-Jan Hottenga,Hilleke E. Hulshoff Pol,Masashi Ikeda,M. Kamran Ikram,Clifford R. Jack,Mark Jenkinson,Robert Johnson,Erik G. Jönsson,Erik G. Jönsson,J. Wouter Jukema,René S. Kahn,Ryota Kanai,Iwona Kłoszewska,David S. Knopman,Peter Kochunov,John B.J. Kwok,John B.J. Kwok,Stephen M. Lawrie,Herve Lemaitre,Herve Lemaitre,Xinmin Liu,Xinmin Liu,Dan L. Longo,W.T. Longstreth,Oscar L. Lopez,Oscar L. Lopez,Simon Lovestone,Simon Lovestone,Oliver Martinez,Jean-Luc Martinot,Jean-Luc Martinot,Venkata S. Mattay,Venkata S. Mattay,Colm McDonald,Andrew M. McIntosh,Katie L. McMahon,Francis J. McMahon,Patrizia Mecocci,Ingrid Melle,Andreas Meyer-Lindenberg,Sebastian Mohnke,Grant W. Montgomery,Derek W. Morris,Derek W. Morris,Thomas H. Mosley,Thomas W. Mühleisen,Bertram Müller-Myhsok,Bertram Müller-Myhsok,Mike A. Nalls,Matthias Nauck,Matthias Nauck,Thomas E. Nichols,Thomas E. Nichols,Wiro J. Niessen,Wiro J. Niessen,Wiro J. Niessen,Markus M. Nöthen,Markus M. Nöthen,Lars Nyberg,Kazutaka Ohi,Rene L. Olvera,Roel A. Ophoff,Roel A. Ophoff,Massimo Pandolfo,Tomáš Paus,Tomáš Paus,Zdenka Pausova,Zdenka Pausova,Brenda W.J.H. Penninx,G. Bruce Pike,Steven G. Potkin,Bruce M. Psaty,Simone Reppermund,Marcella Rietschel,Joshua L. Roffman,Nina Romanczuk-Seiferth,Jerome I. Rotter,Mina Ryten,Mina Ryten,Ralph L. Sacco,Ralph L. Sacco,Perminder S. Sachdev,Perminder S. Sachdev,Andrew J. Saykin,Andrew J. Saykin,Reinhold Schmidt,Peter R. Schofield,Peter R. Schofield,Sigurdur Sigurdsson,Andrew Simmons,Andrew Simmons,Andrew Simmons,Andrew Singleton,Sanjay M. Sisodiya,Colin Smith,Jordan W. Smoller,Jordan W. Smoller,Hilkka Soininen,Hilkka Soininen,Velandai Srikanth,Vidar M. Steen,David J. Stott,Jessika E. Sussmann,Anbupalam Thalamuthu,Henning Tiemeier,Arthur W. Toga,Bryan J. Traynor,Juan C. Troncoso,Jessica A. Turner,Christophe Tzourio,André G. Uitterlinden,André G. Uitterlinden,Maria C. Valdés Hernández,Marcel P. van der Brug,Aad van der Lugt,Nic J A van der Wee,Cornelia M. van Duijn,Neeltje E.M. van Haren,Dennis van 't Ent,Dennis van 't Ent,Marie-José van Tol,Badri N. Vardarajan,Dick J. Veltman,Meike W. Vernooij,Henry Völzke,Henrik Walter,Joanna M. Wardlaw,Thomas H. Wassink,Michael E. Weale,Daniel R. Weinberger,Michael W. Weiner,Wei Wen,Eric Westman,Tonya White,Tien Yin Wong,Tien Yin Wong,Clinton B. Wright,Clinton B. Wright,H. Ronald Zielke,Alan B. Zonderman,Ian J. Deary,Charles DeCarli,Helena Schmidt,Nicholas G. Martin,Anton J. M. de Craen,Margaret J. Wright,Lenore J. Launer,Gunter Schumann,Myriam Fornage,Barbara Franke,Stéphanie Debette,Stéphanie Debette,Sarah E. Medland,M. Arfan Ikram,Paul M. Thompson +435 more
TL;DR: Variants for intracranial volume were also related to childhood and adult cognitive function, and Parkinson's disease, and were enriched near genes involved in growth pathways, including PI3K-AKT signaling.