M
Myron S. Cohen
Researcher at University of North Carolina at Chapel Hill
Publications - 576
Citations - 50913
Myron S. Cohen is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: Population & Acquired immunodeficiency syndrome (AIDS). The author has an hindex of 103, co-authored 549 publications receiving 46021 citations. Previous affiliations of Myron S. Cohen include University of Massachusetts Medical School & Scripps Health.
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Journal ArticleDOI
HIV-1 gp41 envelope IgA is frequently elicited after transmission but has an initial short response half-life
Nicole L. Yates,Andrea Stacey,T L Nolen,Nathan Vandergrift,M. A. Moody,David C. Montefiori,Kent J. Weinhold,William A. Blattner,Persephone Borrow,Robin J. Shattock,Myron S. Cohen,Barton F. Haynes,Georgia D. Tomaras +12 more
TL;DR: HIV-1 transmission frequently elicits mucosal HIV-1 envelope-specific IgA responses targeted to gp41 that have a short half-life, and B-cell-activating factor belonging to the TNF family was elevated immediately preceding the appearance of gp41 Abs, likely contributing to an initial T-independent Ab response.
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Molecular Typing of Neisseria gonorrhoeae Causing Repeated Infections: Evolution of Porin during Passage within a Community
Marcia M. Hobbs,Timothy M. Alcorn,Rachael H. Davis,William A. Fischer,James C. Thomas,Iona M. C. Martin,Catherine A Ison,P. F. Sparling,Myron S. Cohen +8 more
TL;DR: In this paper, the authors compared por gene sequencing, opa-typing, and arbitrarily primed-polymerase chain reaction to identify differences between some isolates belonging to the same serovar.
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Tracking HIV-1 recombination to resolve its contribution to HIV-1 evolution in natural infection.
Hongshuo Song,Elena E. Giorgi,Vitaly V. Ganusov,Fangping Cai,Gayathri Athreya,Hyejin Yoon,Oana Carja,Bhavna Hora,Peter T. Hraber,Ethan Romero-Severson,Chunlai Jiang,Chunlai Jiang,Xiaojun Li,Shuyi Wang,Hui Li,Jesus F. Salazar-Gonzalez,Maria G. Salazar,Nilu Goonetilleke,Brandon F. Keele,David C. Montefiori,Myron S. Cohen,George M. Shaw,Beatrice H. Hahn,Andrew J. McMichael,Barton F. Haynes,Bette T. Korber,Tanmoy Bhattacharya,Tanmoy Bhattacharya,Feng Gao,Feng Gao +29 more
TL;DR: A computational tool is developed to track recombination in patients, identify recombination hot spots, and show contribution of recombination to antibody escape, which provides insight into molecular mechanisms by which viral recombination contributes to HIV-1 persistence and immunopathogenesis.
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Cross-sectional detection of acute HIV infection: timing of transmission, inflammation and antiretroviral therapy.
Oliver Dibben,Jeffrey A. Anderson,Andrea Stacey,Ashley J Mayo,Philip J. Norris,Philip J. Norris,Jo Ann D. Kuruc,Jesus F. Salazar-Gonzalez,Hui Li,Brandon F. Keele,Charles B. Hicks,David M. Margolis,Guido Ferrari,Barton F. Haynes,Ronald Swanstrom,George M. Shaw,Beatrice H. Hahn,Joseph J. Eron,Persephone Borrow,Myron S. Cohen +19 more
TL;DR: Improved AHI detection is urgently needed given the difficulty in recruiting subjects early in AHI, and viral sequence diversity proved accurate in estimating time of infection.
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Promote HIV Chemoprophylaxis Research, Don't Prevent It
Robert M. Grant,Susan Buchbinder,Willard Cates,Edith Clarke,Thomas J. Coates,Myron S. Cohen,Martin Delaney,Guiselly Flores,Pedro Goicochea,Gregg Gonsalves,Mark Harrington,Javier R. Lama,Kathleen M. MacQueen,John P. Moore,Leigh Peterson,Jorge Sanchez,Melanie A. Thompson,Mark A. Wainberg +17 more
TL;DR: The authors of this Policy Forum recommend involvement of community leaders and local investigators early in the development of research projects, open communication of accurate information about research, and active development of prevention and treatment infrastructure, which all serve to build the community trust that is the basis for research into finding ways to stop the spread of HIV/AIDS.