M
Myron S. Cohen
Researcher at University of North Carolina at Chapel Hill
Publications - 576
Citations - 50913
Myron S. Cohen is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: Population & Acquired immunodeficiency syndrome (AIDS). The author has an hindex of 103, co-authored 549 publications receiving 46021 citations. Previous affiliations of Myron S. Cohen include University of Massachusetts Medical School & Scripps Health.
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Journal ArticleDOI
Gonococcal infection: a model of molecular pathogenesis.
TL;DR: Human beings are the only reservoir for the gonococcus, and in spite of public health efforts to control this pathogen, the availability of adequate antibiotic therapy for 40 years, close to a mill...
Journal ArticleDOI
Safety, tolerability, and pharmacokinetics of long-acting injectable cabotegravir in low-risk HIV-uninfected individuals: HPTN 077, a phase 2a randomized controlled trial
Raphael J. Landovitz,Sue Li,Beatriz Grinsztejn,Halima Dawood,Albert Y. Liu,Manya Magnus,Mina C. Hosseinipour,Ravindre Panchia,Leslie Cottle,Gordon Chau,Paul G. Richardson,Mark A. Marzinke,Craig W. Hendrix,Susan H. Eshleman,Yinfeng Zhang,Elizabeth E. Tolley,Jeremy Sugarman,Ryan Kofron,Adeola Adeyeye,David N. Burns,Alex R. Rinehart,David Margolis,William Spreen,Myron S. Cohen,Marybeth McCauley,Joseph J. Eron +25 more
TL;DR: In this study, CAB LA was well tolerated at the doses and dosing intervals used and was not detectable in plasma both at the time of first reactive HIV test and at the study visit 12 weeks prior to the first reactive test.
Journal ArticleDOI
Immunoglobulin Gene Insertions and Deletions in the Affinity Maturation of HIV-1 Broadly Reactive Neutralizing Antibodies
Thomas B. Kepler,Hua-Xin Liao,S. Munir Alam,Rekha Bhaskarabhatla,Ruijun Zhang,Chandri Yandava,Shelley Stewart,Kara Anasti,Garnett Kelsoe,Garnett Kelsoe,Robert Parks,Krissey E. Lloyd,Christina Stolarchuk,Jamie Pritchett,Erika Solomon,Emma Friberg,Lynn Morris,Salim S. Abdool Karim,Myron S. Cohen,Emmanuel B. Walter,Emmanuel B. Walter,M. Anthony Moody,M. Anthony Moody,Xueling Wu,Han Altae-Tran,Ivelin S. Georgiev,Peter D. Kwong,Scott D. Boyd,Andrew Fire,John R. Mascola,Barton F. Haynes,Barton F. Haynes +31 more
TL;DR: The propensity and functional requirement for indels within HIV-1 bnAbs is examined and regimens targeted at sustained activation of bnAb lineages to achieve the required SHM and indel events are designed.
Journal ArticleDOI
Cost-effectiveness of HIV treatment as prevention in serodiscordant couples.
Rochelle P. Walensky,Eric L. Ross,Nagalingeswaran Kumarasamy,Robin Wood,Farzad Noubary,A. David Paltiel,Yoriko M. Nakamura,Sheela Godbole,Ravindre Panchia,Ian Sanne,Milton C. Weinstein,Elena Losina,Kenneth H. Mayer,Kenneth H. Mayer,Ying Q. Chen,Ying Q. Chen,Lei Wang,Lei Wang,Marybeth McCauley,Theresa Gamble,George R. Seage,Myron S. Cohen,Kenneth A. Freedberg +22 more
TL;DR: There is a compelling case for early ART for serodiscordant couples in resource-limited settings and early ART remained very cost-effective over a lifetime under most modeled assumptions in the two countries.
Journal ArticleDOI
Efficacy and safety of three antiretroviral regimens for initial treatment of HIV-1: a randomized clinical trial in diverse multinational settings.
Thomas B. Campbell,Laura M. Smeaton,N. Kumarasamy,Timothy P. Flanigan,Karin L. Klingman,Cynthia Firnhaber,Beatriz Grinsztejn,Mina C. Hosseinipour,Johnstone Kumwenda,Umesh G. Lalloo,Cynthia Riviere,Jorge Sanchez,Marineide Gonçalves de Melo,Khuanchai Supparatpinyo,Srikanth Tripathy,Ana Martinez,Apsara Nair,Ann Walawander,Laura Moran,Yun Chen,Wendy Snowden,James F. Rooney,Jonathan Uy,Robert T. Schooley,Victor De Gruttola,James Hakim,Edith Swann,Ronald L. Barnett,Barbara Brizz,Yvette Delph,Nikki Gettinger,Ronald T. Mitsuyasu,Susan H. Eshleman,Steven A. Safren,Susan A. Fiscus,Adriana Andrade,David W. Haas,Farida Amod,Vladimir Berthaud,Robert C. Bollinger,Yvonne J. Bryson,David D. Celentano,David Chilongozi,Myron S. Cohen,Ann C. Collier,Judith S. Currier,Susan Cu-Uvin,Joseph J. Eron,Charles Flexner,Joel E. Gallant,Roy M. Gulick,Scott M. Hammer,Irving F. Hoffman,Peter N. Kazembe,Newton Kumwenda,Javier R. Lama,Jody Lawrence,Chiedza Maponga,Francis Martinson,Kenneth H. Mayer,Karin Nielsen,Richard B. Pendame,Bharat Ramratnam,Ian Sanne,Patrice Severe,Thira Sirisanthana,Suniti Solomon,Steve Tabet,Taha E. Taha,Charles van der Horst,Christine Wanke,Joan Gormley,Cheryl Marcus,Beverly Putnam,Smanga Ntshele,Edde Loeliger,Keith A. Pappa,Nancy Webb,David Shugarts,Mark A. Winters,Renard S. Descallar,Joseph Steele,Michael Wulfsohn,Farideh Said,Yue Chen,John Martin,Norbert Bischofberger,Andrew K. Cheng,Howard Jaffe,Jabin Sharma,Selvamuthu Poongulali,Sandra W. Cardoso,Deise Lucia Faria,Sima Berendes,Kelly Burke,Rosie Mngqibisa,Cecilia Kanyama,Virginia Kayoyo,Wadzanai Samaneka,Anthony Chisada,Sharla Faesen,Suwat Chariyalertsak,Breno Santos,Rita Alves Lira,Anjali A. Joglekar,Alberto La Rosa,Rosa Infante,Mamta K. Jain,T. Petersen,Sheela Godbole,Sampada Dhayarkar,Judith Feinberg,Jenifer Baer,Richard B. Pollard,David M. Asmuth,Raman R. Gangakhedkar,Asmita Gaikwad,M. Graham Ray,Cathi Basler,Michael F. Para,Kathy J. Watson,Babafemi Taiwo,Donna V. McGregor,Henry H. Balfour,Beth D. Mullan,Ge Youl Kim,Michael K. Klebert,Gary M. Cox,Martha Silberman,Donna Mildvan,Manuel Revuelta,Karen T. Tashima,Helen Patterson,P. Jan Geiseler,Bartolo Santos,Eric S. Daar,Ruben Lopez,Laurie Frarey,David Currin,David H. Haas,Vicki L. Bailey,Pablo Tebas,Larisa Zifchak,Jolene Noel-Connor,Madeline Torres,Beverly E. Sha,Janice M. Fritsche,Michelle S. Cespedes,Janet Forcht,William A. O'Brien,Cheryl Mogridge,Christine Hurley,Roberto Corales,Maria Palmer,Mary Adams,Amneris E. Luque,Luis Lopez-Detres,Todd Stroberg +157 more
TL;DR: Findings of a randomized trial conducted in multiple countries regarding the efficacy of antiretroviral regimens with simplified dosing with positive results are reported.