R
Robin Haw
Researcher at Ontario Institute for Cancer Research
Publications - 51
Citations - 14069
Robin Haw is an academic researcher from Ontario Institute for Cancer Research. The author has contributed to research in topics: Computer science & Gene. The author has an hindex of 22, co-authored 42 publications receiving 11972 citations. Previous affiliations of Robin Haw include University of Toronto & Cold Spring Harbor Laboratory.
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Journal ArticleDOI
The Reactome Pathway Knowledgebase.
Antonio Fabregat,Konstantinos Sidiropoulos,Phani V. Garapati,Marc Gillespie,Marc Gillespie,Kerstin Hausmann,Robin Haw,Bijay Jassal,S Jupe,Florian Korninger,Sheldon J. McKay,Lisa Matthews,Bruce May,Marija Milacic,Karen Rothfels,Veronica Shamovsky,Marissa Webber,Joel Weiser,Mark Williams,Guanming Wu,Lincoln Stein,Lincoln Stein,Lincoln Stein,Henning Hermjakob,Henning Hermjakob,Peter D'Eustachio +25 more
TL;DR: The Reactome Knowledgebase provides molecular details of signal transduction, transport, DNA replication, metabolism and other cellular processes as an ordered network of molecular transformations—an extended version of a classic metabolic map, in a single consistent data model.
Journal ArticleDOI
Global landscape of protein complexes in the yeast Saccharomyces cerevisiae
Nevan J. Krogan,Gerard Cagney,Gerard Cagney,Haiyuan Yu,Gouqing Zhong,Xinghua Guo,Alexandr Ignatchenko,Joyce Li,Shuye Pu,Nira Datta,Aaron Tikuisis,Thanuja Punna,José M. Peregrín-Alvarez,Michael Shales,Xin Zhang,Michael Davey,Mark D. Robinson,Alberto Paccanaro,James E. Bray,Anthony Sheung,Bryan Beattie,Dawn Richards,Veronica Canadien,Atanas Iliev Lalev,Frank Mena,Peter D Wong,Andrei Starostine,Myra M. Canete,James Vlasblom,Samuel Wu,Chris Orsi,Sean R. Collins,Shamanta Chandran,Robin Haw,Jennifer J. Rilstone,Kiran Gandi,Natalie J. Thompson,Gabe Musso,Peter St Onge,Shaun Ghanny,Mandy H. Y. Lam,Gareth Butland,Amin M. Altaf-Ul,Shigehiko Kanaya,Ali Shilatifard,Erin K. O'Shea,Jonathan S. Weissman,C. James Ingles,Timothy P. Hughes,John Parkinson,Mark Gerstein,Shoshana J. Wodak,Andrew Emili,Jack Greenblatt +53 more
TL;DR: T tandem affinity purification was used to process 4,562 different tagged proteins of the yeast Saccharomyces cerevisiae to identify protein–protein interactions, which will help future studies on individual proteins as well as functional genomics and systems biology.
Journal ArticleDOI
Reactome: a database of reactions, pathways and biological processes
David Croft,Gavin O'Kelly,Guanming Wu,Robin Haw,Marc Gillespie,Lisa Matthews,Michael Caudy,Phani V. Garapati,Gopal R. Gopinath,Bijay Jassal,S Jupe,Irina Kalatskaya,Shahana S. Mahajan,Shahana S. Mahajan,Bruce May,Nelson Ndegwa,Esther Schmidt,Veronica Shamovsky,Christina K. Yung,Ewan Birney,Henning Hermjakob,Peter D'Eustachio,Lincoln Stein,Lincoln Stein,Lincoln Stein +24 more
TL;DR: A new web site with improved tools for pathway browsing and data analysis is developed, and orthology-based inferences of pathways in non-human species are made, applying Ensembl Compara to identify orthologs of curated human proteins in each of 20 other species.
Journal ArticleDOI
The BioPAX community standard for pathway data sharing
Emek Demir,Emek Demir,Michael P. Cary,Suzanne M. Paley,Ken Fukuda,Christian Lemer,Imre Vastrik,Guanming Wu,Peter D'Eustachio,Carl F. Schaefer,Joanne S. Luciano,Frank Schacherer,Irma Martínez-Flores,Zhenjun Hu,Verónica Jiménez-Jacinto,Geeta Joshi-Tope,Kumaran Kandasamy,Alejandra López-Fuentes,Huaiyu Mi,Elgar Pichler,Igor Rodchenkov,Andrea Splendiani,Andrea Splendiani,Sasha Tkachev,Jeremy Zucker,Gopal R. Gopinath,Harsha Rajasimha,Harsha Rajasimha,Ranjani Ramakrishnan,Imran Shah,Mustafa H Syed,Nadia Anwar,Özgün Babur,Özgün Babur,Michael L. Blinov,Erik Brauner,Dan Corwin,Sylva L. Donaldson,Frank Gibbons,Robert N. Goldberg,Peter Hornbeck,Augustin Luna,Peter Murray-Rust,Eric K. Neumann,Oliver Reubenacker,Matthias Samwald,Matthias Samwald,Martijn P. van Iersel,Sarala M. Wimalaratne,Keith Allen,Burk Braun,Michelle Whirl-Carrillo,Kei-Hoi Cheung,Kam D. Dahlquist,Andrew Finney,Marc Gillespie,Elizabeth M. Glass,Li Gong,Robin Haw,Michael Honig,Olivier Hubaut,David W. Kane,Shiva Krupa,Martina Kutmon,Julie Leonard,Debbie Marks,David Merberg,Victoria Petri,Alexander R. Pico,Dean Ravenscroft,Liya Ren,Nigam H. Shah,Margot Sunshine,Rebecca Tang,Ryan Whaley,Stan Letovksy,Kenneth H. Buetow,Andrey Rzhetsky,Vincent Schächter,Bruno S. Sobral,Ugur Dogrusoz,Shannon K. McWeeney,Mirit I. Aladjem,Ewan Birney,Julio Collado-Vides,Susumu Goto,Michael Hucka,Nicolas Le Novère,Natalia Maltsev,Akhilesh Pandey,Paul Thomas,Edgar Wingender,Peter D. Karp,Chris Sander,Gary D. Bader +94 more
TL;DR: Thousands of interactions, organized into thousands of pathways, from many organisms are available from a growing number of databases, and this large amount of pathway data in a computable form will support visualization, analysis and biological discovery.
Journal ArticleDOI
The Biomolecular Interaction Network Database and related tools 2005 update
C. Alfarano,C. E. Andrade,K. Anthony,Neil Bahroos,Martha Bajec,Ken Bantoft,Doron Betel,B. Bobechko,Kelly Boutilier,E. Burgess,K. Buzadzija,R. Cavero,C. D'Abreo,Ian Donaldson,D. Dorairajoo,Michel Dumontier,M. R. Dumontier,V. Earles,R. Farrall,Howard J. Feldman,E. Garderman,Y. Gong,R. Gonzaga,V. Grytsan,E. Gryz,V. Gu,E. Haldorsen,A. Halupa,Robin Haw,A. Hrvojic,L. Hurrell,Ruth Isserlin,F. Jack,F. Juma,Asim Khan,T. Kon,S. Konopinsky,V. Le,Eunjung Lee,San Ling,M. Magidin,J. Moniakis,J. Montojo,Susan Moore,Brenda Muskat,Ivan Ng,J. P. Paraiso,Belinda S. Parker,G. Pintilie,R. Pirone,John J. Salama,S. Sgro,T. Shan,Y. Shu,J. Siew,D. Skinner,Kevin A. Snyder,R. Stasiuk,D. Strumpf,Brigitte Tuekam,S. Tao,Z. Wang,Michelle White,R. Willis,Cheryl Wolting,S. Wong,A. Wrong,C. Xin,R. Yao,B. Yates,S. Zhang,K. Zheng,Tony Pawson,Benjamin Ouellette,Christopher W. V. Hogue +74 more
TL;DR: The Biomolecular Interaction Network Database (BIND) archives biomolecular interaction, reaction, complex and pathway information and provides users with methods to discover interactions and molecular mechanisms.