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Roger A. Schultz

Researcher at University of Texas Southwestern Medical Center

Publications -  57
Citations -  26443

Roger A. Schultz is an academic researcher from University of Texas Southwestern Medical Center. The author has contributed to research in topics: Gene & Gene mapping. The author has an hindex of 27, co-authored 57 publications receiving 24988 citations. Previous affiliations of Roger A. Schultz include University of Texas at Dallas.

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Initial sequencing and analysis of the human genome.

Eric S. Lander, +248 more
- 15 Feb 2001 - 
TL;DR: The results of an international collaboration to produce and make freely available a draft sequence of the human genome are reported and an initial analysis is presented, describing some of the insights that can be gleaned from the sequence.
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A Tlr7 translocation accelerates systemic autoimmunity in murine lupus.

TL;DR: Transcription profiling of yaa-bearing B cells revealed the overexpression of a cluster of X-linked genes that included Tlr7, and FISH analysis demonstrated the translocation of this segment onto the yaa chromosome, suggesting that Sles1 modulates the activation of adaptive immunity in response to innate immune signaling.
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Cancer predisposition caused by elevated mitotic recombination in Bloom mice

TL;DR: It is demonstrated that the increased rate of loss of heterozygosity (LOH) resulting from mitotic recombination in vivo constitutes the underlying mechanism causing tumour susceptibility in these mice.
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Structure and localization of the human gene encoding sr-bi/cla-1: evidence for transcriptional control by steroidogenic factor 1

TL;DR: RNA blot analysis of human SR-BI tissues reveals an expression pattern similar to that described previously for rodents with the highest levels of mRNA in the adrenal gland, ovary, and liver, and evidence that it is regulated by the transcription factor, steroidogenic factor 1 (SF-1).