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Yon-Dschun Ko

Researcher at National Institutes of Health

Publications -  91
Citations -  7455

Yon-Dschun Ko is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 32, co-authored 90 publications receiving 6240 citations. Previous affiliations of Yon-Dschun Ko include University of Cologne & Ruhr University Bochum.

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Breast cancer risks associated with missense variants in breast cancer susceptibility genes

Leila Dorling, +135 more
- 15 Sep 2021 - 
TL;DR: In this paper, the authors evaluated breast cancer risks according to five in-silico prediction-of-deleteriousness algorithms, functional protein domain, and frequency, using logistic regression models and also mixture models in which a subset of variants was assumed to be risk-associated.
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Rare Copy Number Variants (CNVs) and Breast Cancer Risk

Joe Dennis, +142 more
- 22 Jun 2021 - 
TL;DR: This is the first genome-wide analysis of rare CNVs in a large breast cancer case-control dataset and detected associations with exonic deletions in established breast cancer susceptibility genes and suggestive associations with non-codingCNVs in known and novel loci with large effects sizes.
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Common variants in breast cancer risk loci predispose to distinct tumor subtypes

Thomas U. Ahearn, +189 more
- 01 Feb 2021 - 
TL;DR: In this article, the authors used two-stage polytomous logistic regression models to evaluate variants in relation to multiple tumor features (ER, progesterone receptor (PR), human epidermal growth factor receptor 2 (HER2) and grade) adjusting for each other.