International Islamic University, Chittagong

About: International Islamic University, Chittagong is a education organization based out in Chittagong, Bangladesh. It is known for research contribution in the topics: Debye model & Density functional theory. The organization has 1111 authors who have published 1089 publications receiving 7918 citations. The organization is also known as: IIUC.

GC-MS Phytochemical Profiling, Pharmacological Properties, and In Silico Studies of Chukrasia velutina Leaves: A Novel Source for Bioactive Agents.

Abstract: Chukrasia velutina is a local medicinal plant commonly known as chikrassy in Bangladesh, India, China, and other South Asian countries. The leaves, bark, and seeds are vastly used as herbal medicine for fever and diarrhea, and its leaves essential oils are used for antimicrobial purposes. In this study, we discuss the neuropsychiatric properties of C. velutina leaves through several animal models, quantitative and qualitative phytochemical analysis, and computational approaches. Neuropsychiatric effects were performed in rodents on the methanolic extract of C. velutina leaves (MECVL). Antidepressant, anxiolytic, and sedative effects experimented through these rodent models were used such as the force swimming test (FST), tail suspension test (TST), hole board test (HBT), elevated plus maze test (EPMT), light/dark box test (LDBT), open field test (OFT), and hole cross test (HCT). In these rodent models, 200 and 400 mg/kg doses were used which exhibited a significant result in the force swimming and tail suspension test (p < 0.001) for the antidepressant effect. In the anxiolytic study, the results were significant in the hole board, elevated plus maze, and light/dark box test (p < 0.001) for doses of 200 and 400 mg/kg. The result was also significant in the open field and hole cross test (p < 0.001) for sedative action in the sake of similar doses. Moreover, qualitative and quantitative studies were also performed through phytochemical screening and GC-MS analysis, and fifty-seven phytochemical compounds were found. These compounds were analyzed for pharmacokinetics properties using the SwissADME tool and from them, thirty-five compounds were considered for the molecular docking analysis. These phytoconstituents were docking against the human serotonin receptor, potassium channel receptor, and crystal structure of human beta-receptor, where eight of the compounds showed a good binding affinity towards the respective receptors considered to the reference standard drugs. After all of these analyses, it can be said that the secondary metabolite of C. velutina leaves (MECVL) could be a good source for inhibiting the neuropsychiatric disorders which were found on animal models as well as in computational studies.

Plant-based indole alkaloids: a comprehensive overview from a pharmacological perspective

Abstract: Plant-based indole alkaloids are very rich in pharmacological activities, and the indole nucleus is considered to contribute greatly to these activities. This review's fundamental objective is to summarize the pharmacological potential of indole alkaloids that have been derived from plants and provide a detailed evaluation of their established pharmacological activities, which may contribute to identifying new lead compounds. The study was performed by searching various scientific databases, including Springer, Elsevier, ACS Publications, Taylor and Francis, Thieme, Wiley Online Library, ProQuest, MDPI, and online scientific books. A total of 100 indole compounds were identified and reviewed. The most active compounds possessed a variety of pharmacological activities, including anticancer, antibacterial, antiviral, antimalarial, antifungal, anti-inflammatory, antidepressant, analgesic, hypotensive, anticholinesterase, antiplatelet, antidiarrheal, spasmolytic, antileishmanial, lipid-lowering, antimycobacterial, and antidiabetic activities. Although some compounds have potent activity, some only have mild-to-moderate activity. The pharmacokinetic profiles of some of the identified compounds, such as brucine, mitragynine, 7-hydroxymitragynine, vindoline, and harmane, were also reviewed. Most of these compounds showed promising pharmacological activity. An in-depth pharmacological evaluation of these compounds should be performed to determine whether any of these indoles may serve as new leads.

Islamic microfinance: the evidence from Australia

Abstract: Purpose – The purpose of this paper is to contribute to the existing body of work in the area of Islamic microfinance by examining the co‐operative nature of Islamic financial services providers (IFSPs) in Australia.Design/methodology/approach – The method employed in this study is a mixture of one of the authors' post‐graduate research and their personal experience, curiosity and association with this industry.Findings – Islamic financial cooperatives, relevant government authorities and Islamic micro‐lenders in Australia should cautiously examine the following opportunities for the development of Islamic microfinance in Australia: merging of Islamic cooperatives with each other for their future growth and development through attracting more capital; integration of microfinancing Islamic investment and retail banking facilities to provide the twin engines of fulfilling communities' religious needs and Australia's economic development; and introducing more creative Islamic microfinance techniques to suit ...

Optimal Planning of Standalone Solar-Wind-Diesel Hybrid Energy System for a Coastal Area of Bangladesh

Abstract: For sustainable development of a country access to electricity in every moment is now the basic need for the current civilization. Power crisis is one of the major barriers for economic development of Bangladesh. Bangladesh lacks in fossil fuel reservation. Abundance of renewable energy sources in the form of solar energy, wind energy provides opportunities of renewable energy based hybrid energy system in the coastal areas of Bnagladesh. Energy generation by hybrid system reduces the generation cost and will help in balancing the cost of energy. Again a standalone renewable enegy incorporated hybrid energy system will reduce load demand from the grid and will be an eco-friendly energy system. This paper proposed a cost effective design of standalone solar-wind-diesel hybrid power system in a coastal area of Bangladesh. Considering different conditions for a coastal area design and simulation of the hybrid power system was performed. Detailed economic analysis and comparison with solar based and diesel based energy system clearly reveals that proposed hybrid power system was found a cost effective solution for coastal areas of bangladesh. DOI: http://dx.doi.org/10.11591/ijece.v2i6.830 Full Text: PDF