Jodhpur National University

About: Jodhpur National University is a education organization based out in Jodhpur, India. It is known for research contribution in the topics: Transdermal & Self-healing hydrogels. The organization has 160 authors who have published 216 publications receiving 2381 citations.

Uses of low copper amalgam alloys in dentistry

Abstract: A filling is the repair of a damaged or decayed tooth, restoring it back to its normal shape, appearance and function. Amalgam Restoration is an example of the material giving its name to the process. Amalgam fillings are made up of mercury, powdered silver and tin. They are mixed and packed into cavities in teeth where it hardens slowly and replaces the missing tooth substance. This article throws light on low copper alloys of dental amalgam, its advantages, disadvantages and contraindications. A review of some patents on amalgam is also provided that summarizes the recent technical advancements taken place in this area.

Anti - Anxiety Drugs An Overview

Abstract: Everyone experiences anxiety at one time or another "butterflies in the stomach" before giving a speech or sweaty palms during a job interview are common symptoms. Other symptoms of anxiety include irritability, uneasiness, jumpiness, feelings of apprehension, rapid or irregular heartbeat, stomach ache, nausea, faintness and breathing problems. An anxiolytic or antipanic or antianxiety agent is a drug used for the treatment of anxiety, and its related psychological and physical symptoms. Anxiolytics have been shown to be useful in the treatment of anxiety disorders. Beta-receptor blockers such as propranolol and oxprenolol, although not anxiolytics, can be used to combat the somatic symptoms of anxiety. Anxiolytics are also known as minor tranquilizers. The term is less common in modern texts, and was originally derived from a dichotomy with major tranquilizers, also known as neuroleptics or antipsychotics.

Ehlers-danlos syndrome- an overview

Abstract: Ehlers-Danlos syndrome, hypermobility type is generally considered the least severe type of EDS, although significant complications, primarily musculoskeletal, can and do occur. The skin is often soft or velvety and may be mildly hyperextensible. Subluxations and dislocations are common; they may occur spontaneously or with minimal trauma and can be acutely painful. Degenerative joint disease is common. Chronic pain, distinct from that associated with acute dislocations or advanced osteoarthritis, is a serious complication of the condition and can be both physically and psychologically disabling. Easy bruising is common.

Pulmonary Arterial Hypertension: Role of Ambrisentan

Abstract: Increasing numbers of experimental investigations and recently also of clinical trials strongly suggest an integral involvement of the endothelin (ET) system in the pathophysiology of a variety of disease states, mainly of the cardiovascular system.Ambrisentan (LU 208075)approved by the US Food and Drug Administration in 2007, a selective ETA-receptor antagonist, is an orally active diphenyl propionic acid derivative that was recently approved for treatment of pulmonary arterial hypertension (PAH) in patients with World Health Organization class II or III symptoms.. It has been shown to have a very promising efficacy to safety ratio in the initial clinical trials. Phase II and Phase III trials with ambrisentan in pulmonary arterial hypertension have been performed. Pulmonary arterial hypertension (PAH) is a rare and progressive disease of the pulmonary arterial circulation that is characterized by a progressive rise in pulmonary vascular resistance, eventually leading to right-heart failure and death. Endothelin (ET) is a potent vasoconstrictor with mitogenic, hypertrophic and pro-inflammatory properties. Therefore, blockade of ET receptors has been suggested as an attractive target in a number of acute and chronic cardiovascular indications, including pulmonary arterial hypertension (PAH), systemic hypertension, and heart failure. In Phase III clinical trials in patients with PAH, ambrisentan (2.5–10 mg orally once-daily) improved exercise capacity, time to clinical worsening, WHO functional class, and quality of life compared with placebo. This review discusses the endothelin family of proteins and receptors and their role in the pathophysiology of pulmonary hypertensive diseases.

Overview of Concept Drifts Detection Methodology in Data Stream

Abstract: Real-time online applications and mobile data generate huge volume of data. There is a need to process this data into compact data structures and extract meaningful information. A number of approaches have been proposed in literature to overcome the issues of data stream mining. This chapter summarizes various issues and application techniques. The chapter is a guideline for research to identify the research issues and select the most appropriate method in order to detect and process novel class.