Institution
Jodhpur National University
Education•Jodhpur, India•
About: Jodhpur National University is a education organization based out in Jodhpur, India. It is known for research contribution in the topics: Transdermal & Self-healing hydrogels. The organization has 160 authors who have published 216 publications receiving 2381 citations.
Topics: Transdermal, Self-healing hydrogels, Swelling, Chitosan, Population
Papers
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TL;DR: In the present study, carboxymethyl chitosan was prepared from chitOSan, crosslinked with glutaraldehyde and evaluated in vitro as a potential carrier for colon targeted drug delivery of ornidazole and showed biphasic release pattern with non-fickian diffusion kinetics at higher pH.
133 citations
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TL;DR: The results of present investigation established sitagliptin treatment attenuated renal damage induced by renal ischemia reperfusion (I/R) in diabetic rats, and confirmed protection against renal I/R in diabetes.
99 citations
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TL;DR: A novel series of Schiff bases of benzothiazole derivatives were synthesized, screened for their antimicrobial activity and structures were elucidated on the basis of elemental analyses and spectral data.
93 citations
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TL;DR: Results indicate that the formulations of S1-S6 synthesized with different cross-linking agents are safe, when tested in experimental animals, as per OECD guidelines 423 and 407.
82 citations
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TL;DR: Investigation of the clinical and histological outcomes of local subgingival application of 0.2% hyaluronic acid gel (GENGIGEL®) as an adjunct to scaling and root planing in chronic periodontitis patients found no additional benefit was found in periodontal parameters.
Abstract: Background: Conventional, non-surgical periodontal therapy consists of supra- and subgingival tooth debridement. However, it is a technically demanding procedure and is not always efficient at eradicating all periodontal pathogens and in reducing inflammation. Therefore, local subgingival application of other chemotherapeutic agents may be used as an adjunct to non-surgical therapy. The aim of this study was to investigate the clinical and histological outcomes of local subgingival application of 0.2% hyaluronic acid gel (GENGIGEL®) as an adjunct to scaling and root planing (SRP) in chronic periodontitis patients. Materials and Methods: One hundred and twenty sites were chosen from 26 patients with chronic periodontitis (criteria being periodontal pockets ≥5mm). Experimental sites additionally received HA gel subgingivally at baseline, 1 st , 2 nd , and 3 rd week. Clinical parameters were re-assessed at 4 th , 6 th , and 12 th week. At 4 th week recall, a gingival biopsy was obtained from test and control site for histologic examination. Results: Intra-group analysis of all the clinical parameters at all sites from baseline to 4 th , 6 th , and 12 th week showed statistically significant changes. Experimental sites showed statistically significant improvement in Gingival index and Bleeding index at 6 th and 12 th week when compared with control sites. However, no statistically significant differences were observed in the PPD and RAL between control and experimental sites at 4 th , 6 th , and 12 th week time interval. No statistically significant association was found between the histological grading of the sites that received HA treatment. Conclusion: Subgingival placement of 0.2% HA gel along with SRP provided a significant improvement in gingival parameters. However, no additional benefit was found in periodontal parameters. Histologically, experimental sites showed reduced inflammatory infiltrate, but it was not statistically significant.
68 citations
Authors
Showing all 162 results
Name | H-index | Papers | Citations |
---|---|---|---|
K. Anand | 2 | 2 | 8 |
Swathi Sharma | 2 | 7 | 13 |
Imran Khan Pathan | 2 | 4 | 9 |
Buhari Lawan Muhammad | 2 | 2 | 7 |
V.R. Choudhary | 2 | 2 | 21 |
Shoaib Kamal | 2 | 2 | 16 |
Preeti Mishra | 2 | 6 | 43 |
Badaru Suleiman | 2 | 2 | 7 |
Yogesh Sharma | 2 | 10 | 16 |
Shailendra Sharma | 2 | 5 | 42 |
Devendra Nagal | 2 | 6 | 11 |
Anjali k | 2 | 2 | 11 |
Gauri Gontiya | 2 | 2 | 74 |
Rahul Trivedi | 2 | 3 | 12 |
Ameet J Kurthukoti | 2 | 2 | 23 |