Jodhpur National University

About: Jodhpur National University is a education organization based out in Jodhpur, India. It is known for research contribution in the topics: Transdermal & Self-healing hydrogels. The organization has 160 authors who have published 216 publications receiving 2381 citations.

Primary caries: an overview

Abstract: Primary caries is an initial lesions produced by direct extension from an external surface. Dental caries is called as tooth decay or a cavity is a disease in which bacterial processes changes carbohydrate to acid which than dematerializes the hard tooth structure like enamel, dentin and cementum. Streptococcus mutans and Lactobacillus are the bacteria responsible for the dental caries by acid production. This article throws light on the dental caries disease, its sign and symptoms, treatment and prevention of it. A review of some patents on dental caries is also provided that summarizes the recent technical advancements taken place in this area.

Design and evaluation of rosiglitazone loaded bio lip strip for translabial drug delivery

Abstract: Rosiglitazone is an oral hypoglycemic agent which undergoes extensive first pass metabolism and having extremely short half-life which make it a possible candidate for delivery through skin The aim of this study was to explore the potentiality of lip skin as a novelistic platform due to its unique histology by formulating Rosiglitazone loaded lip strip using a novel bio material which was isolated from pulp of artocarpus heterophyllus by simplified economical process Rosiglitazone loaded bio lip strips were formulated by using artocarpus heterophyllus biomaterial as a strip former and dextrose as a flexicizer The formulated strip was subjected for various evaluation parameters like moisture content, folding endurance, swelling index, stability studies, in-vitro and in-vivo release Our results revealed that the Rosiglitazone release was extended over a period of 24 hrs This was confirmed by the in-vitro release data Release kinetics of bio strips followed Higuchi model and the mechanism of the drug release was diffusion and anomalous type The results are expressed as mean ± SEM values Statistical significances were evaluated using t test A value of p<005 was considered significant The best formulation was selected on the basis of various evaluated parameters, linearity of drug diffusion rate and used concentration of biomaterial in the formulation The formulated strips are feasible for delivering Rosiglitazone through Translabial route

Orofacial cat bite: a case report.

Abstract: The article describes an unusual case of a 7 years old malechild presenting with orofacial cat bite injury that occurredin infancy. This resulted in loss of deciduous and permanenttooth buds and consequently hampered alveolar growth. Thepatient was given a removable partial denture to restorefunction and aesthetics. The article highlights the importanceof complete history, diagnosis and management of suchinjuries in children.

Effect of rhizomes of Curculigo orchioides on Thioacetamide induced hepatotoxicity.

Abstract: The hepatoprotective activity of methanolic rhizome extract of Curculigo orchioides (MECO) were evaluated against Thioacetamide-induced hepatic damage in rats. The MECO at dose of 100, 200 and 400 mg/kg were administered orally once daily for 21 days and simultaneously administered TAA 100 mg/kg b.w. s.c. 1 h after the respective assigned treatments every 72 h. Serum enzymatic levels of serum glutamate oxaloacetate transaminase (AST), serum glutamate pyruvate transaminase (ALT), serum alkaline phosphatase (ALP) and total bilirubin were estimated along with estimation of superoxide dismutase (SOD) and malondialdehyde (MDA) levels in liver tissues.