Institution
Johannes Kepler University of Linz
Education•Linz, Oberösterreich, Austria•
About: Johannes Kepler University of Linz is a education organization based out in Linz, Oberösterreich, Austria. It is known for research contribution in the topics: Computer science & Thin film. The organization has 6605 authors who have published 19243 publications receiving 385667 citations.
Papers published on a yearly basis
Papers
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04 Dec 2013TL;DR: This paper proposes a novel AL approach that exploits the user's personality - using the Five Factor Model (FFM) - in order to identify the items that the user is requested to rate and significantly increases the number of ratings acquired from the user and the recommendation accuracy.
Abstract: Recommender systems (RSs) suffer from the cold-start or new user/item problem, i.e., the impossibility to provide a new user with accurate recommendations or to recommend new items. Active learning (AL) addresses this problem by actively selecting items to be presented to the user in order to acquire her ratings and hence improve the output of the RS. In this paper, we propose a novel AL approach that exploits the user's personality - using the Five Factor Model (FFM) - in order to identify the items that the user is requested to rate. We have evaluated our approach in a user study by integrating it into a mobile, context-aware RS that provides users with recommendations for places of interest (POIs). We show that the proposed AL approach significantly increases the number of ratings acquired from the user and the recommendation accuracy.
104 citations
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TL;DR: In this article, the socio-economic causes of terrorism and political violence in 12 countries in Western Europe were investigated and the classical economic argument of opportunity cost is confirmed that is, the larger is the set of current economic opportunities for individuals the lower is the likelihood or willingness for them to be involved in a terrorist activity.
104 citations
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TL;DR: The main result of this paper shows that the KH controller approximating function, being a simple fractional function, fulfils the stability condition and can be interpreted as KH controllers are universal approximators in the space of continuous functions.
104 citations
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TL;DR: The results substantiate the conclusion that these devices are the first non-Si optoelectronic platform capable of sufficiently large photovoltages and displacement currents to enable true capacitive stimulation of excitable cells.
Abstract: An efficient nanoscale semiconducting optoelectronic system is reported, which is optimized for neuronal stimulation: the organic electrolytic photocapacitor. The devices comprise a thin (80 nm) trilayer of metal and p-n semiconducting organic nanocrystals. When illuminated in physiological solution, these metal-semiconductor devices charge up, transducing light pulses into localized displacement currents that are strong enough to electrically stimulate neurons with safe light intensities. The devices are freestanding, requiring no wiring or external bias, and are stable in physiological conditions. The semiconductor layers are made using ubiquitous and nontoxic commercial pigments via simple and scalable deposition techniques. It is described how, in physiological media, photovoltage and charging behavior depend on device geometry. To test cell viability and capability of neural stimulation, photostimulation of primary neurons cultured for three weeks on photocapacitor films is shown. Finally, the efficacy of the device is demonstrated by achieving direct optoelectronic stimulation of light-insensitive retinas, proving the potential of this device platform for retinal implant technologies and for stimulation of electrogenic tissues in general. These results substantiate the conclusion that these devices are the first non-Si optoelectronic platform capable of sufficiently large photovoltages and displacement currents to enable true capacitive stimulation of excitable cells.
104 citations
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TL;DR: The method was used to characterize the interaction between human CD4, the major co-receptor in T- cell activation, and human Lck, the protein tyrosine kinase essential for early T-cell signaling, and the known zinc clasp structure had a major impact on the Lck-CD4 interaction.
Abstract: We present a method to identify and characterize interactions between a fluorophore-labeled protein ('prey') and a membrane protein ('bait') in live mammalian cells. Cells are plated on micropatterned surfaces functionalized with antibodies to the bait extracellular domain. Bait-prey interactions are assayed through the redistribution of the fluorescent prey. We used the method to characterize the interaction between human CD4, the major co-receptor in T-cell activation, and human Lck, the protein tyrosine kinase essential for early T-cell signaling. We measured equilibrium associations by quantifying Lck redistribution to CD4 micropatterns and studied interaction dynamics by photobleaching experiments and single-molecule imaging. In addition to the known zinc clasp structure, the Lck membrane anchor in particular had a major impact on the Lck-CD4 interaction, mediating direct binding and further stabilizing the interaction of other Lck domains. In total, membrane anchorage increased the interaction lifetime by two orders of magnitude.
104 citations
Authors
Showing all 6718 results
Name | H-index | Papers | Citations |
---|---|---|---|
Wolfgang Wagner | 156 | 2342 | 123391 |
A. Paul Alivisatos | 146 | 470 | 101741 |
Klaus-Robert Müller | 129 | 764 | 79391 |
Christoph J. Brabec | 120 | 896 | 68188 |
Andreas Heinz | 108 | 1078 | 45002 |
Niyazi Serdar Sariciftci | 99 | 591 | 54055 |
Lars Samuelson | 96 | 850 | 36931 |
Peter J. Oefner | 90 | 348 | 30729 |
Dmitri V. Talapin | 90 | 303 | 39572 |
Tomás Torres | 88 | 625 | 28223 |
Ramesh Raskar | 86 | 670 | 30675 |
Siegfried Bauer | 84 | 422 | 26759 |
Alexander Eychmüller | 82 | 444 | 23688 |
Friedrich Schneider | 82 | 554 | 27383 |
Maksym V. Kovalenko | 81 | 360 | 34805 |