Institution
Kettering University
Education•Flint, Michigan, United States•
About: Kettering University is a education organization based out in Flint, Michigan, United States. It is known for research contribution in the topics: Cancer & RNA. The organization has 6842 authors who have published 7689 publications receiving 337503 citations. The organization is also known as: GMI Engineering & Management Institute & General Motors Institute.
Topics: Cancer, RNA, Antigen, DNA, Population
Papers published on a yearly basis
Papers
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TL;DR: Recent findings on the role of PAR proteins in cell polarity in C. elegans and Drosophila are reviewed, and links that exist between PAR networks and cytoskeletal proteins that both regulate PAR protein localization and act as downstream effectors to elaborate polarity within the cell are emphasized.
Abstract: Cell polarity is essential for cells to divide asymmetrically, form spatially restricted subcellular structures and participate in three-dimensional multicellular organization. PAR proteins are conserved polarity regulators that function by generating cortical landmarks that establish dynamic asymmetries in the distribution of effector proteins. Here, we review recent findings on the role of PAR proteins in cell polarity in C. elegans and Drosophila, and emphasize the links that exist between PAR networks and cytoskeletal proteins that both regulate PAR protein localization and act as downstream effectors to elaborate polarity within the cell.
155 citations
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155 citations
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TL;DR: The PACES-1 Survey as mentioned in this paper was conducted to investigate what students and faculty perceive as cheating and to use this knowledge to help instructors and institutions increase the level of academic integrity among students.
Abstract: Academic dishonesty has become a serious problem at institutions of higher learning. This is particularly true in engineering where, according to previous research, engineering undergraduates are among the most likely to cheat in college. To investigate this concern, the authors embarked on a research project whose goal was to develop a better understanding of what students and faculty perceive as cheating and to use this knowledge to help instructors and institutions increase the level of academic integrity among students. The primary instrument for this project was a seven-page survey that was administered to 643 engineering and pre-engineering undergraduates at eleven institutions, ranging from community colleges to large research universities. This manuscript provides an overview of the descriptive data from the PACES-1 Survey organized around the following questions: what is student cheating and how often does it occur; why do students cheat; and what methods can be used to reduce or stop cheating?
155 citations
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TL;DR: Recent biochemical and structural studies suggest that the exosome core is essential because it coordinates Rrp44 and RrP6 recruitment, RNA can pass through the central channel, and the association with the core modulates Rr p44 andRrp6 activities.
155 citations
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TL;DR: The structure explains why nick sensing is restricted to adenylated ligase and why the 5' phosphate is required for DNA binding and a mechanism of nick recognition and catalysis is proposed supported by mutational data.
155 citations
Authors
Showing all 6853 results
Name | H-index | Papers | Citations |
---|---|---|---|
Joan Massagué | 189 | 408 | 149951 |
Chris Sander | 178 | 713 | 233287 |
Timothy A. Springer | 167 | 669 | 122421 |
Murray F. Brennan | 161 | 925 | 97087 |
Charles M. Rice | 154 | 561 | 83812 |
Lloyd J. Old | 152 | 775 | 101377 |
Howard I. Scher | 151 | 944 | 101737 |
Paul Tempst | 148 | 309 | 89225 |
Pier Paolo Pandolfi | 146 | 529 | 88334 |
Barton F. Haynes | 144 | 911 | 79014 |
Jedd D. Wolchok | 140 | 713 | 123336 |
James P. Allison | 137 | 483 | 83336 |
Harold E. Varmus | 137 | 496 | 76320 |
Scott W. Lowe | 134 | 396 | 89376 |
David S. Klimstra | 133 | 564 | 61682 |