Miami University

About: Miami University is a education organization based out in Oxford, Ohio, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 9949 authors who have published 19598 publications receiving 568410 citations. The organization is also known as: Miami of Ohio & Miami-Ohio.

Lhasa terrane in southern Tibet came from Australia

Abstract: The U-Pb age and Hf isotope data on detrital zircons from Paleozoic metasedimentary rocks in the Lhasa terrane (Tibet) defi ne a distinctive age population of ca. 1170 Ma with e Hf (t) values identical to the coeval detrital zircons from Western Australia, but those from the western Qiangtang and Tethyan Himalaya terranes defi ne an age population of ca. 950 Ma with a similar e Hf (t) range. The ca. 1170 Ma detrital zircons in the Lhasa terrane were most likely derived from the Albany-Fraser belt in southwest Australia, whereas the ca. 950 Ma detrital zircons from both the western Qiangtang and Tethyan Himalaya terranes might have been sourced from the High Himalaya to the south. Such detrital zircon connections enable us to propose that the Lhasa terrane is exotic to the Tibetan Plateau system, and should no longer be considered as part of the Qiangtang‐Greater India‐Tethyan Himalaya continental margin system in the Paleozoic reconstruction of the Indian plate, as current models show; rather, it should be placed at the northwestern margin of Australia. These results provide new constraints on the paleogeographic reconstruction and tectonic evolution of southern Tibet, and indicate that the Lhasa terrane evolved as part of the late Precambrian‐early Paleozoic evolution as part of Australia in a different paleogeographical setting than that of the Qiangtang−Greater India−Tethyan Himalaya system.

The impacts of climate change on ecosystem structure and function

Abstract: Recent climate-change research largely confirms the impacts on US ecosystems identified in the 2009 National Climate Assessment and provides greater mechanistic understanding and geographic specificity for those impacts Pervasive climate-change impacts on ecosystems are those that affect productivity of ecosystems or their ability to process chemical elements Loss of sea ice, rapid warming, and higher organic inputs affect marine and lake productivity, while combined impacts of wildfire and insect outbreaks decrease forest productivity, mostly in the arid and semi-arid West Forests in wetter regions are more productive owing to warming Shifts in species ranges are so extensive that by 2100 they may alter biome composition across 5–20% of US land area Accelerated losses of nutrients from terrestrial ecosystems to receiving waters are caused by both winter warming and intensification of the hydrologic cycle Ecosystem feedbacks, especially those associated with release of carbon dioxide and methane rel

Game Design and Learning: A Conjectural Analysis of How Massively Multiple Online Role-Playing Games (MMORPGs) Foster Intrinsic Motivation

Abstract: During the past two decades, the popularity of computer and video games has prompted games to become a source of study for educational researchers and instructional designers investigating how various aspects of game design might be appropriated, borrowed, and re-purposed for the design of educational materials. The purpose of this paper is to present an analysis of how the structure in massively multiple online role-playing games (MMORPGs) might inform the design of interactive learning and game-based learning environments by looking at the elements which support intrinsic motivation. Specifically, this analysis presents (a) an overview of the two primary elements in MMORPGs game design: character design and narrative environment, (b) a discussion of intrinsic motivation in character role-playing, (c) a discussion of intrinsic motivational supports and cognitive support of the narrative structure of small quests, and (d) a discussion of how the narrative structure of MMORPGs might foster learning in various types of knowledge.

Facile isolation and the characterization of human retinal stem cells

Abstract: This study identifies and characterizes retinal stem cells (RSCs) in early postnatal to seventh-decade human eyes. Different subregions of human eyes were dissociated and cultured by using a clonal sphere-forming assay. The stem cells were derived only from the pars plicata and pars plana of the retinal ciliary margin, at a frequency of ≈1:500. To test for long-term self-renewal, both the sphere assay and monolayer passaging were used. By using the single sphere passaging assay, primary spheres were dissociated and replated, and individual spheres demonstrated 100% self-renewal, with single spheres giving rise to one or more new spheres in each subsequent passage. The clonal retinal spheres were plated under differentiation conditions to assay the differentiation potential of their progeny. The spheres were produced all of the different retinal cell types, demonstrating multipotentiality. Therefore, the human eye contains a small population of cells (≈10,000 cells per eye) that have retinal stem-cell characteristics (proliferation, self-renewal, and multipotentiality). To test the in vivo potential of the stem cells and their progeny, we transplanted dissociated human retinal sphere cells, containing both stem cells and progenitors, into the eyes of postnatal day 1 NOD/SCID mice and embryonic chick eyes. The progeny of the RSCs were able to survive, migrate, integrate, and differentiate into the neural retina, especially as photoreceptors. Their facile isolation, integration, and differentiation suggest that human RSCs eventually may be valuable in treating human retinal diseases.