Roma Tre University

About: Roma Tre University is a education organization based out in Rome, Lazio, Italy. It is known for research contribution in the topics: Large Hadron Collider & Galaxy. The organization has 4434 authors who have published 15352 publications receiving 374888 citations. The organization is also known as: Universita degli Studi Roma Tre & RomaTre.

Data handling, reconstruction, and simulation for the KLOE experiment

Abstract: The broad physics program of the KLOE experiment is based on the high event rate at the Frascati φ factory, and calls for an up-to-date system for data acquisition and processing. In this review of the KLOE offline environment, the architecture of the data-processing system and the programs developed for data reconstruction and Monte Carlo simulation are described, as well as the various procedures used for data handling and transfer between the different components of the system.

An approach to social recommendation for context-aware mobile services

Abstract: Nowadays, several location-based services (LBSs) allow their users to take advantage of information from the Web about points of interest (POIs) such as cultural events or restaurants. To the best of our knowledge, however, none of these provides information taking into account user preferences, or other elements, in addition to location, that contribute to define the context of use. The provided suggestions do not consider, for example, time, day of week, weather, user activity or means of transport. This article describes a social recommender system able to identify user preferences and information needs, thus suggesting personalized recommendations related to POIs in the surroundings of the user's current location. The proposed approach achieves the following goals: (i) to supply, unlike the current LBSs, a methodology for identifying user preferences and needs to be used in the information filtering process; (ii) to exploit the ever-growing amount of information from social networking, user reviews, and local search Web sites; (iii) to establish procedures for defining the context of use to be employed in the recommendation of POIs with low effort. The flexibility of the architecture is such that our approach can be easily extended to any category of POI. Experimental tests carried out on real users enabled us to quantify the benefits of the proposed approach in terms of performance improvement.

Study of (W/Z)H production and Higgs boson couplings using H→ W W∗ decays with the ATLAS detector

Abstract: A search for Higgs boson production in association with a W or Z boson, in the H -> WW* decay channel, is performed with a data sample collected with the ATLAS detector at the LHC in proton-proton collisions at centre-of-mass energies root s = 7 TeV and 8TeV, corresponding to integrated luminosities of 4.5 fb(-1) and 20.3 fb(-1), respectively. The W H production mode is studied in two-lepton and three-lepton final states, while twolepton and four-lepton final states are used to search for the ZH production mode. The observed significance, for the combined WH and ZH production, is 2.5 standard deviations while a significance of 0.9 standard deviations is expected in the Standard Model Higgs boson hypothesis. The ratio of the combined W H and Z H signal yield to the Standard Model expectation, mu(VH), is found to be mu(VH) = 3.0(-1.1)(+1.3)(stat.)(-0.7)(+1.0) (sys.) for the Higgs boson mass of 125.36 GeV. The WH and ZH production modes are also combined with the gluon fusion and vector boson fusion production modes studied in the H -> WW* -> l nu l nu decay channel, resulting in an overall observed significance of 6.5 standard deviations and mu F-gg+VBF+VH = 1.16(-0.15)(+0.16)(stat.)(-0.15)(+0.18)(sys.). The results are interpreted in terms of scaling factors of the Higgs boson couplings to vector bosons (kappa(V)) and fermions (kappa(F)); the combined results are: vertical bar kappa(V)vertical bar = 1.06(-0.10)(+0.10), vertical bar kappa(F)vertical bar = 0.85(-0.20)(+0.26)

Role of ERβ palmitoylation in the inhibition of human colon cancer cell proliferation

Abstract: The cellular functions regulated by 17b-estradiol (E2) start after the hormone binds to its receptors (i.e., ERa and ERb). These act as ligand-dependent transcription factor transactivating target genes. In addition, E2 induces non-genomic actions, whose activation is triggered by a fraction of the ERs localized at the plasma membrane. Palmitoylation allows ERa to localize at the plasma membrane, to associate with caveolin-1, and, upon E2 stimulation, to activate rapid signals relevant for cell proliferation. The existence of a mechanism, which allows ERb localization at the plasma membrane and its putative role in anti-proliferative E2 effects is completely unknown. Here, the susceptibility of ERb to undergo palmitoylation and the role played by this process has been analyzed in DLD-1 containing endogenous ERb or in HeLa cells transiently transfected with ERb or ERa expression vectors. As for ERa, palmitoylation is necessary for ERb localization at the plasma membrane and its association with caveolin-1 but, in contrast to ERa, the E2 binding increases ERb association with caveolin-1 and the p38 member of MAPK family. Moreover, the palmitoyl acyl transferase (PAT) inhibitor blocks the ability of ERb–E2 complex to activate p38 impairing the receptor-dependent activation of downstream pro-apoptotic cascade (i.e., caspase3 activation and poly(ADP-ribose)polymerase (PARP) cleavage). Consequently, palmitoylation must be considered to be a molecular device for ERb, which allows these receptors to interact with the plasma membrane and to regulate E2-induced non-genomic functions relevant to the antiproliferative effect of this hormone.

Measurement of ep→e′pπ+π− and Baryon Resonance Analysis

Abstract: The cross section for the reaction ep→e'ppi(+)pi(-) was measured in the resonance region for 1.4 lt W lt 2.1 GeV and 0.5 lt Q(2) lt 1.5 GeV2/c(2) using the CLAS detector at Jefferson Laboratory. The data show resonant structures not visible in previous experiments. The comparison of our data to a phenomenological prediction using available information on N* and Delta states shows an evident discrepancy. A better description of the data is obtained either by a sizable change of the properties of the P-13(1720) resonance or by introducing a new baryon state, not reported in published analyses.