Institution
Roma Tre University
Education•Rome, Lazio, Italy•
About: Roma Tre University is a education organization based out in Rome, Lazio, Italy. It is known for research contribution in the topics: Large Hadron Collider & Galaxy. The organization has 4434 authors who have published 15352 publications receiving 374888 citations. The organization is also known as: Universita degli Studi Roma Tre & RomaTre.
Papers published on a yearly basis
Papers
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TL;DR: In this article, the authors explore the role of indigenous and foreign innovation efforts in technological change and catching up and their interactions in the emerging economies, and argue that despite the potential offered by globalization and a liberal trade regime, the benefits of international technology diffusion can only be delivered with parallel indigenous innovation efforts and the presence of modern institutional and governance structures.
558 citations
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Vienna University of Technology1, University of Potsdam2, Swedish Meteorological and Hydrological Institute3, University of Messina4, University of Split5, University of Padua6, University of Zagreb7, University of Bologna8, University of Naples Federico II9, Polytechnic University of Turin10, Moscow State University11, Dokuz Eylül University12, University of Bath13, Slovak University of Technology in Bratislava14, Finnish Environment Institute15, Czech Hydrometeorological Institute16, University of Liverpool17, University of Architecture, Civil Engineering and Geodesy18, Technical University of Madrid19, Helmholtz Centre for Environmental Research - UFZ20, ETH Zurich21, Maynooth University22, Polish Academy of Sciences23, ODESSA24, University of Ljubljana25, Roma Tre University26, Norwegian Water Resources and Energy Directorate27, Polytechnic University of Tirana28, University of Belgrade29
TL;DR: Analysis of the timing of river floods in Europe over the past 50 years found clear patterns of changes in flood timing that can be ascribed to climate effects, and highlights the existence of a clear climate signal in flood observations at the continental scale.
Abstract: A warming climate is expected to have an impact on the magnitude and timing of river floods; however, no consistent large-scale climate change signal in observed flood magnitudes has been identified so far. We analyzed the timing of river floods in Europe over the past five decades, using a pan-European database from 4262 observational hydrometric stations, and found clear patterns of change in flood timing. Warmer temperatures have led to earlier spring snowmelt floods throughout northeastern Europe; delayed winter storms associated with polar warming have led to later winter floods around the North Sea and some sectors of the Mediterranean coast; and earlier soil moisture maxima have led to earlier winter floods in western Europe. Our results highlight the existence of a clear climate signal in flood observations at the continental scale.
557 citations
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TL;DR: This review will focus on the recent knowledge about the mechanism by which ERs regulate the expression of target genes and the emerging field of integration of membrane and nuclear receptor signaling, giving examples of the ways by which the genomic and non-genomic actions of ERs on target genes converge.
Abstract: Steroid hormones exert profound effects on cell growth, development, differentiation, and homeostasis. Their effects are mediated through specific intracellular steroid receptors that act via multiple mechanisms. Among others, the action mechanism starting upon 17beta-estradiol (E2) binds to its receptors (ER) is considered a paradigmatic example of how steroid hormones function. Ligand-activated ER dimerizes and translocates in the nucleus where it recognizes specific hormone response elements located in or near promoter DNA regions of target genes. Behind the classical genomic mechanism shared with other steroid hormones, E2 also modulates gene expression by a second indirect mechanism that involves the interaction of ER with other transcription factors which, in turn, bind their cognate DNA elements. In this case, ER modulates the activities of transcription factors such as the activator protein (AP)-1, nuclear factor-kappaB (NF-kappaB) and stimulating protein-1 (Sp-1), by stabilizing DNA-protein complexes and/or recruiting co-activators. In addition, E2 binding to ER may also exert rapid actions that start with the activation of a variety of signal transduction pathways (e.g. ERK/MAPK, p38/MAPK, PI3K/AKT, PLC/PKC). The debate about the contribution of different ER-mediated signaling pathways to coordinate the expression of specific sets of genes is still open. This review will focus on the recent knowledge about the mechanism by which ERs regulate the expression of target genes and the emerging field of integration of membrane and nuclear receptor signaling, giving examples of the ways by which the genomic and non-genomic actions of ERs on target genes converge.
552 citations
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TL;DR: The DarkSide-20k detector as discussed by the authors is a direct WIMP search detector using a two-phase Liquid Argon Time Projection Chamber (LAr TPC) with an active mass of 23 t (20 t).
Abstract: Building on the successful experience in operating the DarkSide-50 detector, the DarkSide Collaboration is going to construct DarkSide-20k, a direct WIMP search detector using a two-phase Liquid Argon Time Projection Chamber (LAr TPC) with an active (fiducial) mass of 23 t (20 t). This paper describes a preliminary design for the experiment, in which the DarkSide-20k LAr TPC is deployed within a shield/veto with a spherical Liquid Scintillator Veto (LSV) inside a cylindrical Water Cherenkov Veto (WCV). This preliminary design provides a baseline for the experiment to achieve its physics goals, while further development work will lead to the final optimization of the detector parameters and an eventual technical design. Operation of DarkSide-50 demonstrated a major reduction in the dominant 39Ar background when using argon extracted from an underground source, before applying pulse shape analysis. Data from DarkSide-50, in combination with MC simulation and analytical modeling, shows that a rejection factor for discrimination between electron and nuclear recoils of $>3 \times 10^{9}$
is achievable. This, along with the use of the veto system and utilizing silicon photomultipliers in the LAr TPC, are the keys to unlocking the path to large LAr TPC detector masses, while maintaining an experiment in which less than $< 0.1$
events (other than $
u$
-induced nuclear recoils) is expected to occur within the WIMP search region during the planned exposure. DarkSide-20k will have ultra-low backgrounds than can be measured in situ, giving sensitivity to WIMP-nucleon cross sections of $1.2 \times 10^{-47}$
cm2 (
$1.1 \times 10^{-46}$
cm2) for WIMPs of 1 TeV/c2 (10 TeV/c2) mass, to be achieved during a 5 yr run producing an exposure of 100 t yr free from any instrumental background.
534 citations
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A. Abada1, Marcello Abbrescia2, Marcello Abbrescia3, Shehu S. AbdusSalam4 +1491 more•Institutions (239)
TL;DR: In this article, the authors present the second volume of the Future Circular Collider Conceptual Design Report, devoted to the electron-positron collider FCC-ee, and present the accelerator design, performance reach, a staged operation scenario, the underlying technologies, civil engineering, technical infrastructure, and an implementation plan.
Abstract: In response to the 2013 Update of the European Strategy for Particle Physics, the Future Circular Collider (FCC) study was launched, as an international collaboration hosted by CERN. This study covers a highest-luminosity high-energy lepton collider (FCC-ee) and an energy-frontier hadron collider (FCC-hh), which could, successively, be installed in the same 100 km tunnel. The scientific capabilities of the integrated FCC programme would serve the worldwide community throughout the 21st century. The FCC study also investigates an LHC energy upgrade, using FCC-hh technology. This document constitutes the second volume of the FCC Conceptual Design Report, devoted to the electron-positron collider FCC-ee. After summarizing the physics discovery opportunities, it presents the accelerator design, performance reach, a staged operation scenario, the underlying technologies, civil engineering, technical infrastructure, and an implementation plan. FCC-ee can be built with today’s technology. Most of the FCC-ee infrastructure could be reused for FCC-hh. Combining concepts from past and present lepton colliders and adding a few novel elements, the FCC-ee design promises outstandingly high luminosity. This will make the FCC-ee a unique precision instrument to study the heaviest known particles (Z, W and H bosons and the top quark), offering great direct and indirect sensitivity to new physics.
526 citations
Authors
Showing all 4598 results
Name | H-index | Papers | Citations |
---|---|---|---|
Andrew White | 149 | 1494 | 113874 |
Sw. Banerjee | 146 | 1906 | 124364 |
Fuqiang Wang | 145 | 1518 | 95014 |
Stefano Giagu | 139 | 1651 | 101569 |
Silvia Masi | 139 | 669 | 97618 |
Filippo Ceradini | 131 | 1016 | 82732 |
Mattias Ellert | 131 | 1022 | 82637 |
Francesco Lacava | 130 | 1042 | 79680 |
Giovanni Organtini | 129 | 1438 | 85866 |
Georg Zobernig | 129 | 1125 | 83321 |
Monica Verducci | 129 | 896 | 76002 |
Marzio Nessi | 129 | 1046 | 78641 |
Cristian Stanescu | 128 | 922 | 76446 |
Domizia Orestano | 128 | 982 | 78297 |
Lashkar Kashif | 128 | 782 | 74072 |