Institution
Roma Tre University
Education•Rome, Lazio, Italy•
About: Roma Tre University is a education organization based out in Rome, Lazio, Italy. It is known for research contribution in the topics: Large Hadron Collider & Galaxy. The organization has 4434 authors who have published 15352 publications receiving 374888 citations. The organization is also known as: Universita degli Studi Roma Tre & RomaTre.
Papers published on a yearly basis
Papers
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TL;DR: It is reported that hyperploid cancer cells become immunogenic because of a constitutive endoplasmic reticulum stress response resulting in the aberrant cell surface exposure of calreticulin, which causes recognition of cancer cells in mice by the host immune system.
Abstract: Cancer cells accommodate multiple genetic and epigenetic alterations that initially activate intrinsic (cell-autonomous) and extrinsic (immune-mediated) oncosuppressive mechanisms. Only once these barriers to oncogenesis have been overcome can malignant growth proceed unrestrained. Tetraploidization can contribute to oncogenesis because hyperploid cells are genomically unstable. We report that hyperploid cancer cells become immunogenic because of a constitutive endoplasmic reticulum stress response resulting in the aberrant cell surface exposure of calreticulin. Hyperploid, calreticulin-exposing cancer cells readily proliferated in immunodeficient mice and conserved their increased DNA content. In contrast, hyperploid cells injected into immunocompetent mice generated tumors only after a delay, and such tumors exhibited reduced DNA content, endoplasmic reticulum stress, and calreticulin exposure. Our results unveil an immunosurveillance system that imposes immunoselection against hyperploidy in carcinogen- and oncogene-induced cancers.
350 citations
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TL;DR: In this article, the authors discuss the possibility that the North Anatolian fault (NAF) results from the deep deformation of the slab beneath the Bitlis-Hellenic subduction zone.
348 citations
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TL;DR: The GW190521 signal is consistent with a binary black hole (BBH) merger source at redshift 0.13-0.30 Gpc-3 yr-1.8 as discussed by the authors.
Abstract: The gravitational-wave signal GW190521 is consistent with a binary black hole (BBH) merger source at redshift 0.8 with unusually high component masses, 85-14+21 M o˙ and 66-18+17 M o˙, compared to previously reported events, and shows mild evidence for spin-induced orbital precession. The primary falls in the mass gap predicted by (pulsational) pair-instability supernova theory, in the approximate range 65-120 M o˙. The probability that at least one of the black holes in GW190521 is in that range is 99.0%. The final mass of the merger (142-16+28 M o˙) classifies it as an intermediate-mass black hole. Under the assumption of a quasi-circular BBH coalescence, we detail the physical properties of GW190521's source binary and its post-merger remnant, including component masses and spin vectors. Three different waveform models, as well as direct comparison to numerical solutions of general relativity, yield consistent estimates of these properties. Tests of strong-field general relativity targeting the merger-ringdown stages of the coalescence indicate consistency of the observed signal with theoretical predictions. We estimate the merger rate of similar systems to be 0.13-0.11+0.30 Gpc-3 yr-1. We discuss the astrophysical implications of GW190521 for stellar collapse and for the possible formation of black holes in the pair-instability mass gap through various channels: via (multiple) stellar coalescences, or via hierarchical mergers of lower-mass black holes in star clusters or in active galactic nuclei. We find it to be unlikely that GW190521 is a strongly lensed signal of a lower-mass black hole binary merger. We also discuss more exotic possible sources for GW190521, including a highly eccentric black hole binary, or a primordial black hole binary.
347 citations
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TL;DR: In this article, the causal relationship between economy and energy was analyzed by adopting a vector error correction model for non-stationary and cointegrated panel data with a large sample of developed and developing countries and four distinct energy sectors.
339 citations
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TL;DR: In this paper, a measurement of the Z/gamma* boson transverse momentum spectrum using ATLAS proton-proton collision data at a centre-of-mass energy of root s = 7TeV at the LHC is described.
Abstract: This paper describes a measurement of the Z/gamma* boson transverse momentum spectrum using ATLAS proton-proton collision data at a centre-of-mass energy of root s = 7TeV at the LHC. The measurement is performed in the Z/gamma* -> e(+)e(-) and Z/gamma* -> mu(+)mu(-) channels, using data corresponding to an integrated luminosity of 4.7 fb(-1). Normalized differential cross sections as a function of the Z/gamma* boson transverse momentum are measured for transverse momenta up to 800 GeV. The measurement is performed inclusively for Z/gamma* rapidities up to 2.4, as well as in three rapidity bins. The channel results are combined, compared to perturbative and resummed QCD calculations and used to constrain the parton shower parameters of Monte Carlo generators.
339 citations
Authors
Showing all 4598 results
Name | H-index | Papers | Citations |
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Andrew White | 149 | 1494 | 113874 |
Sw. Banerjee | 146 | 1906 | 124364 |
Fuqiang Wang | 145 | 1518 | 95014 |
Stefano Giagu | 139 | 1651 | 101569 |
Silvia Masi | 139 | 669 | 97618 |
Filippo Ceradini | 131 | 1016 | 82732 |
Mattias Ellert | 131 | 1022 | 82637 |
Francesco Lacava | 130 | 1042 | 79680 |
Giovanni Organtini | 129 | 1438 | 85866 |
Georg Zobernig | 129 | 1125 | 83321 |
Monica Verducci | 129 | 896 | 76002 |
Marzio Nessi | 129 | 1046 | 78641 |
Cristian Stanescu | 128 | 922 | 76446 |
Domizia Orestano | 128 | 982 | 78297 |
Lashkar Kashif | 128 | 782 | 74072 |