Roma Tre University

About: Roma Tre University is a education organization based out in Rome, Lazio, Italy. It is known for research contribution in the topics: Large Hadron Collider & Galaxy. The organization has 4434 authors who have published 15352 publications receiving 374888 citations. The organization is also known as: Universita degli Studi Roma Tre & RomaTre.

NuSTAR Spectroscopy of Multi-Component X-ray Reflection from NGC 1068

Abstract: We report on observations of NGC1068 with NuSTAR, which provide the best constraints to date on its > 10 keV spectral shape. The NuSTAR data are consistent with past instruments, with no strong continuum or line variability over the past two decades, consistent with its classification as a Compton-thick AGN. The combined NuSTAR, Chandra, XMM-Newton, and Swift BAT spectral dataset offers new insights into the complex secondary emission seen instead of the completely obscured transmitted nuclear continuum. The critical combination of the high signal-to-noise NuSTAR data and the decomposition of the nuclear and extranuclear emission with Chandra allow us to break several model degeneracies and greatly aid physical interpretation. When modeled as a monolithic (i.e., a single N_H) reflector, none of the common Compton-reflection models are able to match the neutral fluorescence lines and broad spectral shape of the Compton reflection without requiring unrealistic physical parameters (e.g., large Fe overabundances, inconsistent viewing angles, poor fits to the spatially resolved spectra). A multi-component reflector with three distinct column densities (e.g., with best-fit values of N_H = 1.5×10^(23), 5×10^(24), and 10^(25) cm^(-2)) provides a more reasonable fit to the spectral lines and Compton hump, with near-solar Fe abundances. In this model, the higher N_H component provides the bulk of the flux to the Compton hump while the lower N_H component produces much of the line emission, effectively decoupling two key features of Compton reflection. We also find that ≈ 30% of the neutral Fe Kɑ line flux arises from >2" (≈140 pc) and is clearly extended, implying that a significant fraction of the <10 keV reflected component arises from regions well outside of a parsec-scale torus. These results likely have ramifications for the interpretation of Compton-thick spectra from observations with poorer signal-to-noise and/or more distant objects.

Strong antioxidant activity of ellagic acid in mammalian cells in vitro revealed by the comet assay.

Abstract: Oxidative stress due to oxygen and various radical species is associated with the induction of DNA single- and double-strand breaks and is considered to be a first step in several human degenerative diseases, cancer and ageing. Naturally occurring antioxidants are being extensively analysed for their ability to protect DNA against such injury. We studied three naturally occuring compounds, Ascorbic Acid, Melatonin and Ellagic acid, for their ability to modulate DNA damage produced by two strong radical oxygen inducers (H2O2 and Bleomycin) in cultured CHO cells. The alkaline Comet assay was used to measure DNA damage and a cytofluorimetric analysis was performed to reveal the intracellular oxidative species. The data showed a marked reduction of H2O2- and Bleomycin-induced DNA damage exerted by Ellagic Acid. On the contrary Ascorbic acid and Melatonin appeared to induce a slight increase in DNA damage per se. In combined treatments, they caused a slight reduction of H2O2-induced damage, but they did not efficiently modulate the Bleomycin-induced one. The Dichlorofluorescein diacetate (DCFH-DA) cytofluorimetric test confirmed the strong scavenging action exerted by Ellagic Acid.