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Institution

Universidade Estadual do Vale do Acaraú

EducationSobral, Brazil
About: Universidade Estadual do Vale do Acaraú is a education organization based out in Sobral, Brazil. It is known for research contribution in the topics: Chalcone & Health promotion. The organization has 205 authors who have published 234 publications receiving 1901 citations.


Papers
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Journal ArticleDOI
25 Dec 2021
TL;DR: In this paper, the authors synthesized thermally responsive copolymers by radical polymerization of the N-isopropylacrylamide (NIPAm) onto the galactomannan (GM) chain.
Abstract: Thermo responsive copolymers were synthesized by radical polymerization of the N-isopropylacrylamide (NIPAm) onto galactomannan (GM) chain. All copolymers showed thermal responsiveness and a critical aggregation concentration (CAC) at 25 °C greater than at 50 °C. Below the lower critical solution temperature (LCST), copolymer nanoparticles presented sizes between 16 and 50 nm, whereas above LCST, they aggregate, presenting sizes in the range 145.8–194.0 nm, depending on NIPAm/GM molar ratio. Amphotericin-B (AmB) was encapsulated in the copolymer nanoparticles with encapsulation efficiency of 41.4 ± 2.76% and 69.0 ± 2.92% respectively for CP1 and CP2. In vitro AmB delivery from the CP1 nanoparticles was found to exhibit controlled release profile. Hemolysis assay was carried out using erythrocytes cells and samples of AmB loaded copolymer nanoparticles (CP1-AmB), unloaded copolymer nanoparticles (CP1) and commercial AmB were evaluated. Unloaded copolymer nanoparticles show hemocompatibility while the percentage of hemolysis of erythrocytes cells for CP1-AmB sample was 8.7 times lower than that observed for commercial AmB. CP1-AmB showed similar minimum inhibitory concentration (MIC) as commercial AmB, in four Candida albicans strains. As CP1-AmB nanoparticle show better hemocompatibility than commercial AmB, this thermo responsive copolymer shows potential as AmB nanocarrier device to be used in fungal infection.

2 citations

Journal ArticleDOI
TL;DR: Feline ovarian tissue was successfully preserved after vitrification in the presence of 74µM betaine loaded in CaCO3 microparticles, as confirmed by morphological analysis and the density of preantral follicles and stromal cells, as well as by the increased mitochondrial activity and decreased production of reactive oxygen species.
Abstract: Ovary fragments from six sexually mature cats were vitrified in the presence or absence of betaine or ascorbic acid, loaded (7.4 or 74µM betaine; 20 or 200µM ascorbic acid) or not (1mM betaine or 0.3mM ascorbic acid) into CaCO3 microparticles, and assessed for follicular morphology, oxidative stress and mitochondrial activity Feline ovarian tissue was successfully preserved after vitrification in the presence of 74µM betaine loaded in CaCO3 microparticles, as confirmed by morphological analysis and the density of preantral follicles and stromal cells, as well as by the increased mitochondrial activity and decreased production of reactive oxygen species.

2 citations

Journal ArticleDOI
01 Dec 2018
TL;DR: É apresentado o levantamento florístico da família Turneraceae no estado do Ceará, Brasil, donde as espécies apresentam ampla distribuição, sendo frequentemente encontradas na vegetação da caatinga, carrasco, cerrado, floresta ombrófila e tabuleiros litorâneos.
Abstract: Resumo E apresentado o levantamento floristico da familia Turneraceae no estado do Ceara, Brasil. Foram reconhecidos dois generos e 22 especies: Piriqueta com sete especies e Turnera com 15, das quais Turnera reginae e uma nova ocorrencia. De modo geral, as especies apresentam ampla distribuicao, sendo frequentemente encontradas na vegetacao da caatinga, carrasco, cerrado, floresta ombrofila e tabuleiros litorâneos, associando-se principalmente a areas abertas e antropizadas. Sao apresentadas fotografias, chaves, descricoes, comentarios gerais e mapas de distribuicao das especies no Ceara.

2 citations

Journal ArticleDOI
TL;DR: The use of natural products in research on tick control for Rhipicephalus microplus is increasing year by year, with promising results as discussed by the authors, and the authors of the present study were the first to evaluate the acaricidal activity of these EOs in solutions prepared using ethanol, dimethylsulfoxide (DMSO) and Tween 80 on larvae and females of R. microplus.

2 citations

Journal Article
TL;DR: The results suggest that the proposed algorithm reduces the total interference, as well as maximizes the packet delivery when compared to existing approaches, mitigating the coexistence problem.

2 citations


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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20227
202126
202036
201925
201829
201720