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Institution

University of Alcalá

EducationAlcalá de Henares, Spain
About: University of Alcalá is a education organization based out in Alcalá de Henares, Spain. It is known for research contribution in the topics: Population & Context (language use). The organization has 10795 authors who have published 20718 publications receiving 410089 citations. The organization is also known as: University of Alcala & University of Alcala de Henares.


Papers
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Journal ArticleDOI
TL;DR: In this paper, the authors evaluated the cracking control ability of Alkali Resistant (AR) glass fibers in standard concrete and Self Compacting Concrete (SCC) and found that the inclusion of low volumetric fractions of the two types of AR-glass fiber under study can control the cracking produced due to very early age shrinkage on both standard concrete this paper.

117 citations

Journal ArticleDOI
TL;DR: In this article, a non-local radiative transfer code was used to model the spectrum of the ultraluminous infrared galaxy Arp 220 and the emission/absorption of all observed features.
Abstract: ISO/LWS grating observations of the ultraluminous infrared galaxy Arp 220 shows absorption in molecular lines of OH, H 2 0 , CH, NH, and "3, well as in the [0 I] 63 pm line and emission in the [C 111 158 pm line. We have modeled the continuum and the emission/absorption of all observed features by means of a non-local radiative transfer code. The continuum from 25 to 1300 pm is modeled AS A WARM (106 K) NUCLEAR REGION THAT IS OPTICALLY THICK IN THE FAR-INFRARED, attenuated by an extended region (size 2") that is heated mainly through absorption of nuclear infrared radiation. The molecular absorption in the nuclear region is characterized by high excitation due to the high infrared radiation density. The OH column densities are high toward the nucleus and the extended region (about 2 x 10 sup 17 cm sup-2). The H2O column density is also high toward the nucleus (2 - 10 x 1017 cm-2) and lower in the extended region. The column densities in a halo that accounts for the absorption by the lowest lying levels are similar to what are found in the diffuse clouds toward the star forming regions in the Sgr B2 molecular cloud complex near the Galactic Center. Most notable are the high column densities found for NH and NH3 toward the nucleus, with values of about 1.5 x 10supl6 cmsup-2 and about 3 x 10supl6 cmsup-2, respectively, whereas the NH2 column density is lower than about 2 x 10sup15 cmsup-2. A combination of PDRs in the extended region and hot cores with enhanced H20 photodissociation and a possible shock contribution in the nuclei may explain the relative column densities of OH and H20, whereas the nitrogen chemistry may be strongly affected by cosmic ray ionization. The [C II] 158 pm line is well reproduced by our models and its "deficit" relative to the CII/FIR ratio in normal and starburst galaxies is suggested to be mainly a consequence of the dominant non-PDR component of far- infrared radiation, ALTHOUGH OUR MODELS ALONE CANNOT RULE OUT EXTINCTION EFFECTS IN THE NUCLEI.

117 citations

Journal ArticleDOI
TL;DR: The development of tubular involution with age is similar to that observed after experimental ischemia, suggesting that vascular lesions may play an important role in age-related testicular atrophy.
Abstract: The ultrastructure of the progressive testicular involution with advancing age in men is reviewed. There is no definite age at which testicular involution begins, and the onset and severity of testicular lesions are subjected to pronounced individual variations. Hormone studies also indicate great individual variations, and subtle changes in both the testis and the pituitary develop progressively with age. Testicular size, sperm quality, and numbers of all germ cell types, Sertoli cells, and Ley dig cells decrease with age. The volume occupied by the seminiferous tubules decreases, whereas that occupied by the testicular interstitium remains constant. The most frequent histological pattern of the aging testis is a mosaic of different seminiferous tubule lesions, varying from tubules with complete, although reduced, spermatogenesis, to completely sclerosed tubules. The tubules with complete spermatogenesis may show numerous morphological abnormalities in the germ cells, including multinucleation. Abnormal germ cells degenerate causing Sertoli cell vacuolation. These vacuoles correspond to dilations of the extracellular spaces resulting from the premature exfoliation of germ cells. Degenerating cells that are phagocytosed by the Sertoli cells give rise to an accumulation of lipid droplets in the Sertoli cell cytoplasm. The loss of germ cells begins with the spermatids, but progressively affects the earlier germ cell types, and tubules with maturation arrest at the level of the spermatocytes or spermatogonia are observed. The Sertoli cells show morphological abnormalities such as dedifferentiation, mitochondrial metaplasia, and multinucleation. Germ cell loss is associated with thickening of the tunica propria. When all seminiferous epithelial cells have disappeared, only an intensely collagenized tunica propria with myoid cells remains (sclerosed tubules). The Ley dig cells progressively dedifferentiate with a decrease in the quantity of both smooth endoplasmic reticulum and mitochondria, together with an accumulation of lipid droplets, crystalline inclusions, and residual bodies, and formation of multinucleate cells. The development of tubular involution with age is similar to that observed after exprimental ischemia, suggesting that vascular lesions may play an important role in age-related testicular atrophy.

117 citations

Journal ArticleDOI
TL;DR: The remarkable structural resemblances between aloins and the pharmacophore structure of inhibitory tetracyclines, suggest that the inhibitory effects ofAloins are via an interaction between the carbonyl group at C(9) and an adjacent hydroxyl group of anthrone at the secondary binding site of enzyme, destabilizing the structure of granulocyte MMPs.

117 citations

Journal ArticleDOI
TL;DR: It was observed that there could be a potential increased risk of developing cancer over a lifetime from exposure to arsenic (As) through ingestion of the soils studied (oral intake), as well as an increase risk of cancer due to inhalation of chromium (Cr) present in re-suspended soils from the industrial area.

117 citations


Authors

Showing all 10907 results

NameH-indexPapersCitations
José Luis Zamorano105695133396
Jesús F. San Miguel9752744918
Sebastián F. Sánchez9662932496
Javier P. Gisbert9599033726
Luis M. Ruilope9484197778
Luis M. Garcia-Segura8848427077
Alberto Orfao8559737670
Amadeo R. Fernández-Alba8331821458
Rafael Luque8069328395
Francisco Rodríguez7974824992
Andrea Negri7924235311
Rafael Cantón7857529702
David J. Grignon7830123119
Christophe Baudouin7455322068
Josep M. Argilés7331019675
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20251
20243
202375
2022166
20211,660
20201,532