Institution
University of Alcalá
Education•Alcalá de Henares, Spain•
About: University of Alcalá is a education organization based out in Alcalá de Henares, Spain. It is known for research contribution in the topics: Population & Context (language use). The organization has 10795 authors who have published 20718 publications receiving 410089 citations. The organization is also known as: University of Alcala & University of Alcala de Henares.
Topics: Population, Context (language use), Medicine, Receptor, Computer science
Papers published on a yearly basis
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TL;DR: The electrostatic assembly of the electrochemical interface and the catalytic layers resulted in integrated biochemical systems in which mass transfer diffusion and heterogeneous catalytic and electron transfer steps are efficiently coupled and can be easily manipulated.
103 citations
Shanghai Jiao Tong University1, Goethe University Frankfurt2, Hospital General Universitario Gregorio Marañón3, University of Barcelona4, Iuliu Hațieganu University of Medicine and Pharmacy5, University of Paris6, University of Alcalá7, Autonomous University of Barcelona8, University of Toulouse9, Autonomous University of Madrid10, Katholieke Universiteit Leuven11, University of Copenhagen12, Medical University of Vienna13, Aarhus University Hospital14, University of Padua15, University of Alberta16, Martin Luther University of Halle-Wittenberg17, University of Bonn18, Odense University Hospital19, University of Bern20, Complutense University of Madrid21
TL;DR: This large multi-center international real-life study identified ACLF as at admission an independent predictor of rebleeding and mortality in AVB and pTIPS may be considered in ACLF patients with AVB, although the presented data need to be independently validated.
103 citations
TL;DR: Observed patterns are due to the human-induced sympatry of species with different evolutionary histories whose flowering phenology evolved under different climatic regimes, and suggest different implications for impacts at evolutionary time scales among the three regions.
102 citations
TL;DR: Improved knowledge of stacking interactions may lead to a better understanding of the architecture and inherent flexibility of particular DNA sequences and may provide insight into the principles that dictate the structural changes and specificity patterns observed in the binding of some intercalating ligands to DNA.
102 citations
TL;DR: The enhancement of PDT effectiveness by combining it with other therapeutic modalities has become an interesting field in NMSC research, and new strategies open the way to a wider improvement of the prevention and eradication of skin cancer.
Abstract: Non-melanoma skin cancer (NMSC) is the most common form of cancer in the Caucasian population. Among NMSC types, basal cell carcinoma (BCC) has the highest incidence and squamous cell carcinoma (SCC) is less common although it can metastasize, accounting for the majority of NMSC-related deaths. Treatment options for NMSC include both surgical and non-surgical modalities. Even though surgical approaches are most commonly used to treat these lesions, Photodynamic Therapy (PDT) has the advantage of being a non-invasive option, and capable of field treatment, providing optimum cosmetic outcomes. Numerous clinical research studies have shown the efficacy of PDT for treating pre-malignant and malignant NMSC. However, resistant or recurrent tumors appear and sometimes become more aggressive. In this sense, the enhancement of PDT effectiveness by combining it with other therapeutic modalities has become an interesting field in NMSC research. Depending on the characteristics and the type of tumor, PDT can be applied in combination with immunomodulatory (Imiquimod) and chemotherapeutic (5-fluorouracil, methotrexate, diclofenac, or ingenol mebutate) agents, inhibitors of some molecules implicated in the carcinogenic process (COX2 or MAPK), surgical techniques, or even radiotherapy. These new strategies open the way to a wider improvement of the prevention and eradication of skin cancer.
102 citations
Authors
Showing all 10907 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| José Luis Zamorano | 105 | 695 | 133396 |
| Jesús F. San Miguel | 97 | 527 | 44918 |
| Sebastián F. Sánchez | 96 | 629 | 32496 |
| Javier P. Gisbert | 95 | 990 | 33726 |
| Luis M. Ruilope | 94 | 841 | 97778 |
| Luis M. Garcia-Segura | 88 | 484 | 27077 |
| Alberto Orfao | 85 | 597 | 37670 |
| Amadeo R. Fernández-Alba | 83 | 318 | 21458 |
| Rafael Luque | 80 | 693 | 28395 |
| Francisco Rodríguez | 79 | 748 | 24992 |
| Andrea Negri | 79 | 242 | 35311 |
| Rafael Cantón | 78 | 575 | 29702 |
| David J. Grignon | 78 | 301 | 23119 |
| Christophe Baudouin | 74 | 553 | 22068 |
| Josep M. Argilés | 73 | 310 | 19675 |