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Showing papers by "University of Alcalá published in 2019"


Journal ArticleDOI
TL;DR: Climate change strongly impacts regions in high latitudes and altitudes that store high amounts of carbon in yet frozen ground, and the authors show that the consequence of these changes is global warming of permafrost at depths greater than 10 m in the Northern Hemisphere, in mountains, and in Antarctica.
Abstract: Permafrost warming has the potential to amplify global climate change, because when frozen sediments thaw it unlocks soil organic carbon. Yet to date, no globally consistent assessment of permafrost temperature change has been compiled. Here we use a global data set of permafrost temperature time series from the Global Terrestrial Network for Permafrost to evaluate temperature change across permafrost regions for the period since the International Polar Year (2007–2009). During the reference decade between 2007 and 2016, ground temperature near the depth of zero annual amplitude in the continuous permafrost zone increased by 0.39 ± 0.15 °C. Over the same period, discontinuous permafrost warmed by 0.20 ± 0.10 °C. Permafrost in mountains warmed by 0.19 ± 0.05 °C and in Antarctica by 0.37 ± 0.10 °C. Globally, permafrost temperature increased by 0.29 ± 0.12 °C. The observed trend follows the Arctic amplification of air temperature increase in the Northern Hemisphere. In the discontinuous zone, however, ground warming occurred due to increased snow thickness while air temperature remained statistically unchanged.

906 citations


Journal ArticleDOI
TL;DR: The OpenMolcas environment is described and features unique to simulations of spectroscopic and magnetic phenomena such as the exact semiclassical description of the interaction between light and matter, various X-ray processes, magnetic circular dichroism and properties are described.
Abstract: In this Article we describe the OpenMolcas environment and invite the computational chemistry community to collaborate. The open-source project already includes a large number of new developments realized during the transition from the commercial MOLCAS product to the open-source platform. The paper initially describes the technical details of the new software development platform. This is followed by brief presentations of many new methods, implementations, and features of the OpenMolcas program suite. These developments include novel wave function methods such as stochastic complete active space self-consistent field, density matrix renormalization group (DMRG) methods, and hybrid multiconfigurational wave function and density functional theory models. Some of these implementations include an array of additional options and functionalities. The paper proceeds and describes developments related to explorations of potential energy surfaces. Here we present methods for the optimization of conical intersections, the simulation of adiabatic and nonadiabatic molecular dynamics, and interfaces to tools for semiclassical and quantum mechanical nuclear dynamics. Furthermore, the Article describes features unique to simulations of spectroscopic and magnetic phenomena such as the exact semiclassical description of the interaction between light and matter, various X-ray processes, magnetic circular dichroism, and properties. Finally, the paper describes a number of built-in and add-on features to support the OpenMolcas platform with postcalculation analysis and visualization, a multiscale simulation option using frozen-density embedding theory, and new electronic and muonic basis sets.

559 citations


Journal ArticleDOI
TL;DR: The main purpose of this paper is to outline the state of the art and to identify open challenges concerning the most relevant areas within bio-inspired optimization, thereby highlighting the need for reaching a consensus and joining forces towards achieving valuable insights into the understanding of this family of optimization techniques.
Abstract: In recent years, the research community has witnessed an explosion of literature dealing with the mimicking of behavioral patterns and social phenomena observed in nature towards efficiently solving complex computational tasks. This trend has been especially dramatic in what relates to optimization problems, mainly due to the unprecedented complexity of problem instances, arising from a diverse spectrum of domains such as transportation, logistics, energy, climate, social networks, health and industry 4.0, among many others. Notwithstanding this upsurge of activity, research in this vibrant topic should be steered towards certain areas that, despite their eventual value and impact on the field of bio-inspired computation, still remain insufficiently explored to date. The main purpose of this paper is to outline the state of the art and to identify open challenges concerning the most relevant areas within bio-inspired optimization. An analysis and discussion are also carried out over the general trajectory followed in recent years by the community working in this field, thereby highlighting the need for reaching a consensus and joining forces towards achieving valuable insights into the understanding of this family of optimization techniques.

401 citations



Journal ArticleDOI
26 Apr 2019-Science
TL;DR: A framework for rewilding actions that can serve as a guideline for researchers and managers and aims to promote beneficial interactions between society and nature, and identifies trophic complexity, stochastic disturbances, and dispersal as three critical components of natural ecosystem dynamics.
Abstract: BACKGROUND Rapid global change is creating fundamental challenges for the persistence of natural ecosystems and their biodiversity. Conservation efforts aimed at the protection of landscapes have had mixed success, and there is an increasing awareness that the long-term protection of biodiversity requires inclusion of flexible restoration along with protection. Rewilding is one such approach that has been both promoted and criticized in recent years. Proponents emphasize the potential of rewilding to tap opportunities for restoration while creating benefits for both ecosystems and societies. Critics discuss the lack of a consistent definition of rewilding and insufficient knowledge about its potential outcomes. Other criticisms arise from the mistaken notion that rewilding actions are planned without considering societal acceptability and benefits. Here, we present a framework for rewilding actions that can serve as a guideline for researchers and managers. The framework is applicable to a variety of rewilding approaches, ranging from passive to trophic rewilding, and aims to promote beneficial interactions between society and nature. ADVANCES The concept of rewilding has evolved from its initial emphasis on protecting large, connected areas for large carnivore conservation to a process-oriented, dynamic approach. On the basis of concepts from resilience and complexity theory of social-ecological systems, we identify trophic complexity, stochastic disturbances, and dispersal as three critical components of natural ecosystem dynamics. We propose that the restoration of these processes, and their interactions, can lead to increased self-sustainability of ecosystems and should be at the core of rewilding actions. Building on these concepts, we develop a framework to design and evaluate rewilding plans. Alongside ecological restoration goals, our framework emphasizes people’s perceptions and experiences of wildness and the regulating and material contributions from restoring nature. These societal aspects are important outcomes and may be critical factors for the success of rewilding initiatives (see the figure). We further identify current societal constraints on rewilding and suggest actions to mitigate them. OUTLOOK The concept of rewilding challenges us to rethink the way we manage nature and to broaden our vision about how nature will respond to changes that society brings, both intentionally and unintentionally. The effects of rewilding actions will be specific to each ecosystem, and thus a deep understanding of the processes that shape ecosystems is critical to anticipate these effects and to take appropriate management actions. In addition, the decision of whether a rewilding approach is desirable should consider stakeholders’ needs and expectations. To this end, structured restoration planning—based on participatory processes involving researchers, managers, and stakeholders—that includes monitoring and adaptive management can be used. With the recent designation of 2021–2030 as the “decade of ecosystem restoration” by the United Nations General Assembly, policy- and decision-makers could push rewilding topics to the forefront of discussions about how to reach post-2020 biodiversity goals.

259 citations


Journal ArticleDOI
TL;DR: In this article, the authors explore the physical basis to detect burned areas from satellite observations, describes the historical trends of using satellite sensors to monitor burned areas, summarizes the most recent approaches to map burned areas and evaluates the existing burned area products (both at global and regional scales).

247 citations


Journal ArticleDOI
TL;DR: In this paper, a locally adapted multitemporal two-phase burned area (BA) algorithm has been developed using as inputs Sentinel-2 MSI reflectance measurements in the short and near infrared wavebands plus the active fires detected by Terra and Aqua MODIS sensors.

231 citations


Journal ArticleDOI
Helen Phillips1, Carlos A. Guerra2, Marie Luise Carolina Bartz3, Maria J. I. Briones4, George G. Brown5, Thomas W. Crowther6, Olga Ferlian1, Konstantin B. Gongalsky7, Johan van den Hoogen6, Julia Krebs1, Alberto Orgiazzi, Devin Routh6, Benjamin Schwarz8, Elizabeth M. Bach, Joanne M. Bennett2, Ulrich Brose9, Thibaud Decaëns, Birgitta König-Ries9, Michel Loreau, Jérôme Mathieu, Christian Mulder10, Wim H. van der Putten11, Kelly S. Ramirez, Matthias C. Rillig12, David J. Russell13, Michiel Rutgers, Madhav P. Thakur, Franciska T. de Vries, Diana H. Wall14, David A. Wardle, Miwa Arai15, Fredrick O. Ayuke16, Geoff H. Baker17, Robin Beauséjour, José Camilo Bedano18, Klaus Birkhofer19, Eric Blanchart, Bernd Blossey20, Thomas Bolger21, Robert L. Bradley, Mac A. Callaham22, Yvan Capowiez, Mark E. Caulfield11, Amy Choi23, Felicity Crotty24, Andrea Dávalos25, Andrea Dávalos20, Darío J. Díaz Cosín, Anahí Domínguez18, Andrés Esteban Duhour26, Nick van Eekeren, Christoph Emmerling27, Liliana B. Falco26, Rosa Fernández, Steven J. Fonte14, Carlos Fragoso, André L.C. Franco, Martine Fugère, Abegail T Fusilero28, Shaieste Gholami29, Michael J. Gundale, Mónica Gutiérrez López, Davorka K. Hackenberger30, Luis M. Hernández, Takuo Hishi31, Andrew R. Holdsworth32, Martin Holmstrup33, Kristine N. Hopfensperger34, Esperanza Huerta Lwanga11, Veikko Huhta, Tunsisa T. Hurisso35, Tunsisa T. Hurisso14, Basil V. Iannone, Madalina Iordache36, Monika Joschko, Nobuhiro Kaneko37, Radoslava Kanianska38, Aidan M. Keith39, Courtland Kelly14, Maria Kernecker, Jonatan Klaminder, Armand W. Koné40, Yahya Kooch41, Sanna T. Kukkonen, H. Lalthanzara42, Daniel R. Lammel12, Daniel R. Lammel43, Iurii M. Lebedev7, Yiqing Li44, Juan B. Jesús Lidón, Noa Kekuewa Lincoln45, Scott R. Loss46, Raphaël Marichal, Radim Matula, Jan Hendrik Moos47, Gerardo Moreno48, Alejandro Morón-Ríos, Bart Muys49, Johan Neirynck50, Lindsey Norgrove, Marta Novo, Visa Nuutinen51, Victoria Nuzzo, Mujeeb Rahman P, Johan Pansu17, Shishir Paudel46, Guénola Pérès, Lorenzo Pérez-Camacho52, Raúl Piñeiro, Jean-François Ponge, Muhammad Rashid53, Muhammad Rashid54, Salvador Rebollo52, Javier Rodeiro-Iglesias4, Miguel Á. Rodríguez52, Alexander M. Roth55, Guillaume Xavier Rousseau56, Anna Rożen57, Ehsan Sayad29, Loes van Schaik58, Bryant C. Scharenbroch59, Michael Schirrmann60, Olaf Schmidt21, Boris Schröder61, Julia Seeber62, Maxim Shashkov63, Maxim Shashkov64, Jaswinder Singh65, Sandy M. Smith23, Michael Steinwandter, José Antonio Talavera66, Dolores Trigo, Jiro Tsukamoto67, Anne W. de Valença, Steven J. Vanek14, Iñigo Virto68, Adrian A. Wackett55, Matthew W. Warren, Nathaniel H. Wehr, Joann K. Whalen69, Michael B. Wironen70, Volkmar Wolters71, Irina V. Zenkova, Weixin Zhang72, Erin K. Cameron73, Nico Eisenhauer1 
Leipzig University1, Martin Luther University of Halle-Wittenberg2, Universidade Positivo3, University of Vigo4, Empresa Brasileira de Pesquisa Agropecuária5, ETH Zurich6, Moscow State University7, University of Freiburg8, University of Jena9, University of Catania10, Wageningen University and Research Centre11, Free University of Berlin12, Senckenberg Museum13, Colorado State University14, National Agriculture and Food Research Organization15, University of Nairobi16, Commonwealth Scientific and Industrial Research Organisation17, National Scientific and Technical Research Council18, Brandenburg University of Technology19, Cornell University20, University College Dublin21, United States Forest Service22, University of Toronto23, Aberystwyth University24, State University of New York at Cortland25, National University of Luján26, University of Trier27, University of the Philippines Mindanao28, Razi University29, Josip Juraj Strossmayer University of Osijek30, Kyushu University31, Minnesota Pollution Control Agency32, Aarhus University33, Northern Kentucky University34, Lincoln University (Missouri)35, University of Agricultural Sciences, Dharwad36, Fukushima University37, Matej Bel University38, Lancaster University39, Université d'Abobo-Adjamé40, Tarbiat Modares University41, Pachhunga University College42, University of São Paulo43, University of Hawaii at Hilo44, College of Tropical Agriculture and Human Resources45, Oklahoma State University–Stillwater46, Forest Research Institute47, University of Extremadura48, Katholieke Universiteit Leuven49, Research Institute for Nature and Forest50, Natural Resources Institute Finland51, University of Alcalá52, COMSATS Institute of Information Technology53, King Abdulaziz University54, University of Minnesota55, Federal University of Maranhão56, Jagiellonian University57, Technical University of Berlin58, University of Wisconsin-Madison59, Leibniz Association60, Braunschweig University of Technology61, University of Innsbruck62, Russian Academy of Sciences63, Keldysh Institute of Applied Mathematics64, Khalsa College, Amritsar65, University of La Laguna66, Kōchi University67, Universidad Pública de Navarra68, McGill University69, The Nature Conservancy70, University of Giessen71, Henan University72, University of Saint Mary73
25 Oct 2019-Science
TL;DR: It was found that local species richness and abundance typically peaked at higher latitudes, displaying patterns opposite to those observed in aboveground organisms, which suggest that climate change may have serious implications for earthworm communities and for the functions they provide.
Abstract: Soil organisms, including earthworms, are a key component of terrestrial ecosystems. However, little is known about their diversity, their distribution, and the threats affecting them. We compiled a global dataset of sampled earthworm communities from 6928 sites in 57 countries as a basis for predicting patterns in earthworm diversity, abundance, and biomass. We found that local species richness and abundance typically peaked at higher latitudes, displaying patterns opposite to those observed in aboveground organisms. However, high species dissimilarity across tropical locations may cause diversity across the entirety of the tropics to be higher than elsewhere. Climate variables were found to be more important in shaping earthworm communities than soil properties or habitat cover. These findings suggest that climate change may have serious implications for earthworm communities and for the functions they provide.

223 citations


Journal ArticleDOI
TL;DR: Observations of microseism, local surface gravity waves, and a teleseismic earthquake along a 4192-sensor ocean-bottom DAS array offshore Belgium are reported, suggesting significant potential of DAS in next-generation submarine seismic networks.
Abstract: Sparse seismic instrumentation in the oceans limits our understanding of deep Earth dynamics and submarine earthquakes. Distributed acoustic sensing (DAS), an emerging technology that converts optical fiber to seismic sensors, allows us to leverage pre-existing submarine telecommunication cables for seismic monitoring. Here we report observations of microseism, local surface gravity waves, and a teleseismic earthquake along a 4192-sensor ocean-bottom DAS array offshore Belgium. We observe in-situ how opposing groups of ocean surface gravity waves generate double-frequency seismic Scholte waves, as described by the Longuet-Higgins theory of microseism generation. We also extract P- and S-wave phases from the 2018-08-19 [Formula: see text] Fiji deep earthquake in the 0.01-1 Hz frequency band, though waveform fidelity is low at high frequencies. These results suggest significant potential of DAS in next-generation submarine seismic networks.

214 citations


Journal ArticleDOI
TL;DR: In this paper, the effects of secondary nanoplastics of polyhydroxybutyrate (PHB), a biodegradable plastic, on three representative organisms of aquatic ecosystems were investigated.
Abstract: Over the last five decades, plastics production has increased as a consequence of their use in strategic sectors causing damage on aquatic ecosystems. In this context, biodegradable plastics have emerged as an ecological alternative because they are easily degradable in the environment. Despite the recent advances in the field of plastic ecotoxicology, the ecological impact of secondary nanoplastics (nanoplastics resulting from natural degradation of micro and macro plastics) in the environment remains poorly understood. Here, we have investigated the effects of secondary nanoplastics of polyhydroxybutyrate (PHB), a biodegradable plastic, on three representative organisms of aquatic ecosystems. Secondary PHB-nanoplastics were produced from PHB-microplastics by abiotic degradation under environmentally representative conditions. Secondary PHB-nanoplastics induced a significant decrease in cellular growth and altered relevant physiological parameters in all organisms. We investigated whether the observed toxicity was exerted by PHB-nanoplastics themselves or by other abiotic degradation products released from PHB-microplastics. An experiment was run in which PHB-nanoplastics were removed by ultrafiltration; the resulting supernatant was not toxic to the organisms, ruling out the presence of toxic chemicals in the PHB-microplastics. In addition, we have performed a complete physicochemical characterization confirming the presence of secondary PHB-nanoplastics in the 75–200 nm range. All results put together indicated that secondary PHB-nanoplastics released as a consequence of abiotic degradation of PHB-microplastics were harmful for the tested organisms, suggesting that biodegradable plastic does not mean safe for the environment in the case of PHB.

193 citations


Journal ArticleDOI
TL;DR: The results suggest that fundamentally different patterns of thermal limits found among the earth's realms may be largely explained by differences in episodic thermal extremes among realms, updating global macrophysiological ‘rules’.
Abstract: Linking variation in species' traits to large-scale environmental gradients can lend insight into the evolutionary processes that have shaped functional diversity and future responses to environmental change. Here, we ask how heat and cold tolerance vary as a function of latitude, elevation and climate extremes, using an extensive global dataset of ectotherm and endotherm thermal tolerance limits, while accounting for methodological variation in acclimation temperature, ramping rate and duration of exposure among studies. We show that previously reported relationships between thermal limits and latitude in ectotherms are robust to variation in methods. Heat tolerance of terrestrial ectotherms declined marginally towards higher latitudes and did not vary with elevation, whereas heat tolerance of freshwater and marine ectotherms declined more steeply with latitude. By contrast, cold tolerance limits declined steeply with latitude in marine, intertidal, freshwater and terrestrial ectotherms, and towards higher elevations on land. In all realms, both upper and lower thermal tolerance limits increased with extreme daily temperature, suggesting that different experienced climate extremes across realms explain the patterns, as predicted under the Climate Extremes Hypothesis. Statistically accounting for methodological variation in acclimation temperature, ramping rate and exposure duration improved model fits, and increased slopes with extreme ambient temperature. Our results suggest that fundamentally different patterns of thermal limits found among the earth's realms may be largely explained by differences in episodic thermal extremes among realms, updating global macrophysiological 'rules'. This article is part of the theme issue 'Physiological diversity, biodiversity patterns and global climate change: testing key hypotheses involving temperature and oxygen'.

Journal ArticleDOI
TL;DR: Examination of students' acceptance of technology and the process of adopting an online learning environment incorporating web-based resources, such as virtual laboratories, interactive activities, and educational videos, and a game-based learning methodology indicates that efficiency, playfulness, and students' degree of satisfaction are factors that positively influence the original TAM variables and students's acceptance of this technology.
Abstract: The development of Internet technologies and new ways of sharing information has facilitated the emergence of a variety of elearning scenarios. However, in technological areas such as engineering, where students must carry out hands-on exercises and laboratory work essential for their learning, it is not so easy to design online environments for practicals. The aim of this experimental study was to examine students' acceptance of technology and the process of adopting an online learning environment incorporating web-based resources, such as virtual laboratories, interactive activities, and educational videos, and a game-based learning methodology. To this end, their responses to an online questionnaire (n = 223) were analyzed using structural equation modeling. The study was based on the technology acceptance model (TAM), but included and assessed other factors such as perceived efficiency, playfulness, and satisfaction, which are not explained by the TAM. Our results confirm that this extension of the TAM provides a useful theoretical model to help understand and explain users' acceptance of an online learning environment incorporating virtual laboratory and practical work. Our results also indicate that efficiency, playfulness, and students' degree of satisfaction are factors that positively influence the original TAM variables and students' acceptance of this technology. Here, we also discuss the significant theoretical and spractical implications for educational use of these web-based resources.

Journal ArticleDOI
TL;DR: In this paper, the role of resources, competences, and dynamic capabilities (RCCs) as determinants (drivers and barriers) of different eco-innovation (EI) types is analyzed.
Abstract: Firms are influenced by internal factors (resources and capabilities) and external factors (e.g., regulation) when taking the decision to eco‐innovate. However, the analysis of the internal factors has received much less attention than the external ones. This paper aims to fill this gap in the literature by analyzing the role of resources, competences, and dynamic capabilities (RCCs) as determinants (drivers and barriers) of different eco‐innovation (EI) types. Those EI types contribute differently to the sustainable transition of the economy and society, that is, towards the circular economy. The statistical analyses reveal that RCCs are quite relevant as determinants of EIs, and that different RCCs are more or less relevant for different EI types. In particular, the determinants of systemic and radical EIs substantially differ from those for continuous improvements. Our results suggest that physical RCCs, involvement in green supply chains, an EI‐friendly corporate culture, technology‐push and market‐pull, and internal financing resources represent drivers to these EIs, whereas cooperation, organizational learning, an ISO (International Organization for Standardization) ecological certification, and technological path dependency are barriers. The results may guide firms to pursue competitive and sustainable advantage by innovating through certain EI types corresponding to available and dedicated RCCs. They may also be useful to policy makers who are willing to promote specific EI types.

Journal ArticleDOI
TL;DR: The ability to monitor tear glucose outside the eye and the utility of wearable devices for monitoring vitamin nutrients in connection to enzymatic flow detector and rapid voltammetric scanning are demonstrated, paving the way for an effective eyeglasses system capable of chemical tear analysis.

Journal ArticleDOI
TL;DR: This review analyzes the relationship between microvesicles and reactive oxygen species (ROS) and finds that Endothelial microvesicle, in particular, contain a specific and well-developed antioxidant machinery that is especially suitable for eliminating ROS in the extracellular compartment.
Abstract: This review analyzes the relationship between microvesicles and reactive oxygen species (ROS). This relationship is bidirectional; on the one hand, the number and content of microvesicles produced by the cells are affected by oxidative stress conditions; on the other hand, microvesicles can directly and/or indirectly modify the ROS content in the extra- as well as the intracellular compartments. In this regard, microvesicles contain a pro-oxidant or antioxidant machinery that may produce or scavenge ROS: direct effect. This mechanism is especially suitable for eliminating ROS in the extracellular compartment. Endothelial microvesicles, in particular, contain a specific and well-developed antioxidant machinery. On the other hand, the molecules included in microvesicles can modify (activate or inhibit) ROS metabolism in their target cells: indirect effect. This can be achieved by the incorporation into the cells of ROS metabolic enzymes included in the microvesicles, or by the regulation of signaling pathways involved in ROS metabolism. Proteins, as well as miRNAs, are involved in this last effect.

Journal ArticleDOI
TL;DR: In this article, a detection method for long-lasting and large-scale summer heatwaves, using a local, climatological 99th percentile threshold, based on present-climate (1976-2005) daily SST.
Abstract: Extreme ocean warming events, known as marine heatwaves (MHWs), have been observed to perturb significantly marine ecosystems and fisheries around the world. Here, we propose a detection method for long-lasting and large-scale summer MHWs, using a local, climatological 99th percentile threshold, based on present-climate (1976–2005) daily SST. To assess their future evolution in the Mediterranean Sea we use, for the first time, a dedicated ensemble of fully-coupled Regional Climate System Models from the Med-CORDEX initiative and a multi-scenario approach. The models appear to simulate well MHW properties during historical period, despite biases in mean and extreme SST. In response to increasing greenhouse gas forcing, the events become stronger and more intense under RCP4.5 and RCP8.5 than RCP2.6. By 2100 and under RCP8.5, simulations project at least one long-lasting MHW every year, up to three months longer, about 4 times more intense and 42 times more severe than present-day events. They are expected to occur from June-October and to affect at peak the entire basin. Their evolution is found to occur mainly due to an increase in the mean SST, but increased daily SST variability also plays a noticeable role. Until the mid-21st century, MHW characteristics rise independently of the choice of the emission scenario, the influence of which becomes more evident by the end of the period. Further analysis reveals different climate change responses in certain configurations, more likely linked to their driving global climate model rather than to the individual model biases.

Journal ArticleDOI
TL;DR: A global assessment of NNT effects on the three main categories of ecosystem services, including regulating (RES), provisioning and cultural services (PES) and on an ecosystem disservice (EDS), and a quantitative understanding of the complex synergies, trade‐offs and context dependencies involved is provided.
Abstract: Non-native tree (NNT) species have been transported worldwide to create or enhance services that are fundamental for human well-being, such as timber provision, erosion control or ornamental value; yet NNTs can also produce undesired effects, such as fire proneness or pollen allergenicity. Despite the variety of effects that NNTs have on multiple ecosystem services, a global quantitative assessment of their costs and benefits is still lacking. Such information is critical for decision-making, management and sustainable exploitation of NNTs. We present here a global assessment of NNT effects on the three main categories of ecosystem services, including regulating (RES), provisioning (PES) and cultural services (CES), and on an ecosystem disservice (EDS), i.e. pollen allergenicity. By searching the scientific literature, country forestry reports, and social media, we compiled a global data set of 1683 case studies from over 125 NNT species, covering 44 countries, all continents but Antarctica, and seven biomes. Using different meta-analysis techniques, we found that, while NNTs increase most RES (e.g. climate regulation, soil erosion control, fertility and formation), they decrease PES (e.g. NNTs contribute less than native trees to global timber provision). Also, they have different effects on CES (e.g. increase aesthetic values but decrease scientific interest), and no effect on the EDS considered. NNT effects on each ecosystem (dis)service showed a strong context dependency, varying across NNT types, biomes and socio-economic conditions. For instance, some RES are increased more by NNTs able to fix atmospheric nitrogen, and when the ecosystem is located in low-latitude biomes; some CES are increased more by NNTs in less-wealthy countries or in countries with higher gross domestic products. The effects of NNTs on several ecosystem (dis)services exhibited some synergies (e.g. among soil fertility, soil formation and climate regulation or between aesthetic values and pollen allergenicity), but also trade-offs (e.g. between fire regulation and soil erosion control). Our analyses provide a quantitative understanding of the complex synergies, trade-offs and context dependencies involved for the effects of NNTs that is essential for attaining a sustained provision of ecosystem services.

Journal ArticleDOI
TL;DR: The progress in the search for synthetic routes for alkenyl boronates and their use in a variety of organic transformations is accounted.
Abstract: Organoboron compounds have become one of the most versatile building blocks in organic synthesis owing to their accessible and efficient conversion into many different functional groups. In particular, alkenyl boronates have received a great deal of attention as very reactive substrates in Suzuki-Miyaura cross-coupling reactions. Accordingly, efforts towards the development of efficient methods to prepare this type of compound are ongoing. In this contribution, the progress in the search for synthetic routes for alkenyl boronates and their use in a variety of organic transformations is accounted.

Journal ArticleDOI
TL;DR: Results are consistent with most of the associations previously found between these patterns and breast, prostate and gastric cancer risk and indicate that consuming whole fruits, vegetables, legumes, olive oil, nuts, and fish and avoiding red and processed meat, refined grains, sweets, caloric drinks, juices, convenience food, and sauces might reduce CRC risk.
Abstract: To assess if the associations found between three previously identified dietary patterns with breast, prostate and gastric cancer are also observed for colorectal cancer (CRC). MCC-Spain is a multicase-control study that collected information of 1629 incident cases of CRC and 3509 population-based controls from 11 Spanish provinces. Western, Prudent and Mediterranean data-driven dietary patterns—derived in another Spanish case-control study—were reconstructed in MCC-Spain. Their association with CRC was assessed using mixed multivariable logistic regression models considering a possible interaction with sex. Risk by tumor site (proximal colon, distal colon, and rectum) was evaluated using multinomial regression models. While no effect of the Prudent pattern on CRC risk was observed, a high adherence to the Western dietary pattern was associated with increased CRC risk for both males [ORfourth(Q4) vs. first(Q1)quartile (95% CI): 1.45 (1.11;1.91)] and females [ORQ4 vs. Q1 (95% CI): 1.50 (1.07;2.09)] but seem to be confined to distal colon [ORfourth(Q4) vs. first(Q1)quartile (95% CI): 2.02 (1.44;2.84)] and rectal [ORQ4 vs. Q1 (95% CI): 1.46 (1.05;2.01)] tumors. The protective effect of the Mediterranean dietary pattern against CRC was observed for both sexes [males: ORQ4 vs. Q1 (95% CI): 0.71 (0.55;0.92); females: ORQ4 vs. Q1 (95% CI): 0.56 (0.40;0.77)] and for all cancer sites: proximal colon [ORQ4 vs. Q1 (95% CI): 0.70 (0.51;0.97)], distal colon [ORQ4 vs. Q1 (95% CI): 0.65 (0.48;0.89)], and rectum (ORQ4 vs. Q1 (95% CI): 0.60 (0.45;0.81)]. Our results are consistent with most of the associations previously found between these patterns and breast, prostate and gastric cancer risk and indicate that consuming whole fruits, vegetables, legumes, olive oil, nuts, and fish and avoiding red and processed meat, refined grains, sweets, caloric drinks, juices, convenience food, and sauces might reduce CRC risk.

Journal ArticleDOI
TL;DR: A method to predict future pedestrian paths, poses, and intentions up to 1 s in advance based on balanced Gaussian process dynamical models (B-GPDMs), which reduce the 3-D time-related information extracted from key points or joints placed along pedestrian bodies into low-dimensional spaces.
Abstract: According to several reports published by worldwide organizations, thousands of pedestrians die in road accidents every year. Due to this fact, vehicular technologies have been evolving with the intent of reducing these fatalities. This evolution has not finished yet, since, for instance, the predictions of pedestrian paths could improve the current automatic emergency braking systems. For this reason, this paper proposes a method to predict future pedestrian paths, poses, and intentions up to 1 s in advance. This method is based on balanced Gaussian process dynamical models (B-GPDMs), which reduce the 3-D time-related information extracted from key points or joints placed along pedestrian bodies into low-dimensional spaces. The B-GPDM is also capable of inferring future latent positions and reconstruct their associated observations. However, learning a generic model for all kinds of pedestrian activities normally provides less accurate predictions. For this reason, the proposed method obtains multiple models of four types of activity, i.e., walking, stopping, starting, and standing, and selects the most similar model to estimate future pedestrian states. This method detects starting activities 125 ms after the gait initiation with an accuracy of 80% and recognizes stopping intentions 58.33 ms before the event with an accuracy of 70%. Concerning the path prediction, the mean error for stopping activities at a time-to-event (TTE) of 1 s is 238.01 ± 206.93 mm and, for starting actions, the mean error at a TTE of 0 s is 331.93 ± 254.73 mm.

Journal ArticleDOI
TL;DR: Liver cirrhosis but not portal hypertension per se grossly impairs the endothelial and muco-epithelial barriers promoting PBT to the portal-venous circulation and thus, gut-liver-axis.

Journal ArticleDOI
TL;DR: Novel species of fungi described in this study include those from various countries as follows: Australia, Chaetomella pseudocircinoseta and Coniella pseudodiospyri on Eucalyptus microcorys leaves, Cladophialophora eucalyPTi, TeratosphaeriaDunnii and Vermiculariopsiella dunnii on EUCalypti leaves, Cylindrium grande and Hypsotheca e
Abstract: Novel species of fungi described in this study include those from various countries as follows: Australia, Chaetomella pseudocircinoseta and Coniella pseudodiospyri on Eucalyptus microcorys leaves, Cladophialophora eucalypti, Teratosphaeria dunnii and Vermiculariopsiella dunnii on Eucalyptus dunnii leaves, Cylindrium grande and Hypsotheca eucalyptorum on Eucalyptus grandis leaves, Elsinoe salignae on Eucalyptus saligna leaves, Marasmius lebeliae on litter of regenerating subtropical rainforest, Phialoseptomonium eucalypti (incl. Phialoseptomonium gen. nov.) on Eucalyptus grandis × camaldulensis leaves, Phlogicylindrium pawpawense on Eucalyptus tereticornis leaves, Phyllosticta longicauda as an endophyte from healthy Eustrephus latifolius leaves, Pseudosydowia eucalyptorum on Eucalyptus sp. leaves, Saitozyma wallum on Banksia aemula leaves, Teratosphaeria henryi on Corymbia henryi leaves. Brazil, Aspergillus bezerrae, Backusella azygospora, Mariannaea terricola and Talaromyces pernambucoensis from soil, Calonectria matogrossensis on Eucalyptus urophylla leaves, Calvatia brasiliensis on soil, Carcinomyces nordestinensis on Bromelia antiacantha leaves, Dendryphiella stromaticola on small branches of an unidentified plant, Nigrospora brasiliensis on Nopalea cochenillifera leaves, Penicillium alagoense as a leaf endophyte on a Miconia sp., Podosordaria nigrobrunnea on dung, Spegazzinia bromeliacearum as a leaf endophyte on Tilandsia catimbauensis, Xylobolus brasiliensis on decaying wood. Bulgaria, Kazachstania molopis from the gut of the beetle Molops piceus. Croatia, Mollisia endocrystallina from a fallen decorticated Picea abies tree trunk. Ecuador, Hygrocybe rodomaculata on soil. Hungary, Alfoldia vorosii (incl. Alfoldia gen. nov.) from Juniperus communis roots, Kiskunsagia ubrizsyi (incl. Kiskunsagia gen. nov.) from Fumana procumbens roots. India, Aureobasidium tremulum as laboratory contaminant, Leucosporidium himalayensis and Naganishia indica from windblown dust on glaciers. Italy, Neodevriesia cycadicola on Cycas sp. leaves, Pseudocercospora pseudomyrticola on Myrtus communis leaves, Ramularia pistaciae on Pistacia lentiscus leaves, Neognomoniopsis quercina (incl. Neognomoniopsis gen. nov.) on Quercus ilex leaves. Japan, Diaporthe fructicola on Passiflora edulis × P. edulis f. flavicarpa fruit, Entoloma nipponicum on leaf litter in a mixed Cryptomeria japonica and Acer spp. forest. Macedonia, Astraeus macedonicus on soil. Malaysia, Fusicladium eucalyptigenum on Eucalyptus sp. twigs, Neoacrodontiella eucalypti (incl. Neoacrodontiella gen. nov.) on Eucalyptus urophylla leaves. Mozambique, Meliola gorongosensis on dead Philenoptera violacea leaflets. Nepal, Coniochaeta dendrobiicola from Dendriobium lognicornu roots. New Zealand, Neodevriesia sexualis and Thozetella neonivea on Archontophoenix cunninghamiana leaves. Norway, Calophoma sandfjordenica from a piece of board on a rocky shoreline, Clavaria parvispora on soil, Didymella finnmarkica from a piece of Pinus sylvestris driftwood. Poland, Sugiyamaella trypani from soil. Portugal, Colletotrichum feijoicola from Acca sellowiana. Russia, Crepidotus tobolensis on Populus tremula debris, Entoloma ekaterinae, Entoloma erhardii and Suillus gastroflavus on soil, Nakazawaea ambrosiae from the galleries of Ips typographus under the bark of Picea abies. Slovenia, Pluteus ludwigii on twigs of broadleaved trees. South Africa, Anungitiomyces stellenboschiensis (incl. Anungitiomyces gen. nov.) and Niesslia stellenboschiana on Eucalyptus sp. leaves, Beltraniella pseudoportoricensis on Podocarpus falcatus leaf litter, Corynespora encephalarti on Encephalartos sp. leaves, Cytospora pavettae on Pavetta revoluta leaves, Helminthosporium erythrinicola on Erythrina humeana leaves, Helminthosporium syzygii on a Syzygium sp. bark canker, Libertasomyces aloeticus on Aloe sp. leaves, Penicillium lunae from Musa sp. fruit, Phyllosticta lauridiae on Lauridia tetragona leaves, Pseudotruncatella bolusanthi (incl. Pseudotruncatellaceae fam. nov.) and Dactylella bolusanthi on Bolusanthus speciosus leaves. Spain, Apenidiella foetida on submerged plant debris, Inocybe grammatoides on Quercus ilex subsp. ilex forest humus, Ossicaulis salomii on soil, Phialemonium guarroi from soil. Thailand, Pantospora chromolaenae on Chromolaena odorata leaves. Ukraine, Cadophora helianthi from Helianthus annuus stems. USA, Boletus pseudopinophilus on soil under slash pine, Botryotrichum foricae, Penicillium americanum and Penicillium minnesotense from air. Vietnam, Lycoperdon vietnamense on soil. Morphological and culture characteristics are supported by DNA barcodes.

Proceedings ArticleDOI
09 Jun 2019
TL;DR: Diverse options such as enlarging the dataset to cover these domains in unsupervised training or adapting the images on-the-fly during inference to a comfortable domain such as sunny daylight in a pre-processing step are explored, allowing IV perception systems to work reliably also at night.
Abstract: Perception in autonomous vehicles has progressed exponentially in the last years thanks to the advances of vision-based methods such as Convolutional Neural Networks (CNNs). Current deep networks are both efficient and reliable, at least in standard conditions, standing as a suitable solution for the perception tasks of autonomous vehicles. However, there is a large accuracy downgrade when these methods are taken to adverse conditions such as nighttime. In this paper, we study methods to alleviate this accuracy gap by using recent techniques such as Generative Adversarial Networks (GANs). We explore diverse options such as enlarging the dataset to cover these domains in unsupervised training or adapting the images on-the-fly during inference to a comfortable domain such as sunny daylight in a pre-processing step. The results show some interesting insights and demonstrate that both proposed approaches considerably reduce the domain gap, allowing IV perception systems to work reliably also at night.

Journal ArticleDOI
02 Aug 2019
TL;DR: This systematic review and meta-analysis examines the association between birth by cesarean delivery and risk of neurodevelopmental and psychiatric disorders in the offspring compared with birth by vaginal delivery.
Abstract: Importance Birth by cesarean delivery is increasing globally, particularly cesarean deliveries without medical indication. Children born via cesarean delivery may have an increased risk of negative health outcomes, but the evidence for psychiatric disorders is incomplete. Objective To evaluate the association between cesarean delivery and risk of neurodevelopmental and psychiatric disorders in the offspring. Data Sources Ovid MEDLINE, Embase, Web of Science, and PsycINFO were searched from inception to December 19, 2018. Search terms included all main mental disorders in theDiagnostic and Statistical Manual of Mental Disorders(Fifth Edition). Study Selection Two researchers independently selected observational studies that examined the association between cesarean delivery and neurodevelopmental and psychiatric disorders in the offspring. Data Extraction and Synthesis Two researchers independently extracted data according to Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) and Meta-analysis of Observational Studies in Epidemiology (MOOSE) reporting guidelines and assessed study quality using the Newcastle-Ottawa Scale. Random-effects meta-analyses were used to pool odds ratios (ORs) with 95% CIs for each outcome. Sensitivity and influence analyses tested the robustness of the results. Main Outcomes and Measures The ORs for the offspring with any neurodevelopmental or psychiatric disorder who were born via cesarean delivery compared with those were born via vaginal delivery. Results A total of 6953 articles were identified, of which 61 studies comprising 67 independent samples were included, totaling 20 607 935 deliveries. Compared with offspring born by vaginal delivery, offspring born via cesarean delivery had increased odds of autism spectrum disorders (OR, 1.33; 95% CI, 1.25-1.41;I2 = 69.5%) and attention-deficit/hyperactivity disorder (OR, 1.17; 95% CI, 1.07-1.26;I2 = 79.2%). Estimates were less precise for intellectual disabilities (OR, 1.83; 95% CI, 0.90-3.70;I2 = 88.2%), obsessive-compulsive disorder (OR, 1.49; 95% CI, 0.87-2.56;I2 = 67.3%), tic disorders (OR, 1.31; 95% CI, 0.98-1.76;I2 = 75.6%), and eating disorders (OR, 1.18; 95% CI, 0.96-1.47;I2 = 92.7%). No significant associations were found with depression/affective psychoses or nonaffective psychoses. Estimates were comparable for emergency and elective cesarean delivery. Study quality was high for 82% of the cohort studies and 50% of the case-control studies. Conclusions and Relevance The findings suggest that cesarean delivery births are associated with an increased risk of autism spectrum disorder and attention-deficit/hyperactivity disorder, irrespective of cesarean delivery modality, compared with vaginal delivery. Future studies on the mechanisms behind these associations appear to be warranted.

Journal ArticleDOI
TL;DR: This initial demonstration of glucose monitoring introduces new possibilities for metabolites monitoring in infants and neonates using saliva as a non-invasive sample, representing the first wearable sensor focusing on chemical saliva sensing in newborns.
Abstract: Wearable sensors for noninvasive monitoring of physiological parameters is a growing technology in the clinical field. Especially in neonates, the development of portable and nonharmful monitoring ...

Journal ArticleDOI
TL;DR: The assessment of functional and structural development of a HM-exposed soil allowed evaluation on the cellular adaptive responses to the tested environmental stresses, and provided valuable information to assist developing effective remediation strategies of HMs polluted soils using bacteria as the remediator.

Journal ArticleDOI
TL;DR: In this paper, a pattern-oriented model evaluation approach using the random forest (RF) algorithm was developed to identify emergent relationships between climate, vegetation, and socio-economic predictor variables and burned area.
Abstract: . Recent climate changes have increased fire-prone weather conditions in many regions and have likely affected fire occurrence, which might impact ecosystem functioning, biogeochemical cycles, and society. Prediction of how fire impacts may change in the future is difficult because of the complexity of the controls on fire occurrence and burned area. Here we aim to assess how process-based fire-enabled dynamic global vegetation models (DGVMs) represent relationships between controlling factors and burned area. We developed a pattern-oriented model evaluation approach using the random forest (RF) algorithm to identify emergent relationships between climate, vegetation, and socio-economic predictor variables and burned area. We applied this approach to monthly burned area time series for the period from 2005 to 2011 from satellite observations and from DGVMs from the “Fire Modeling Intercomparison Project” (FireMIP) that were run using a common protocol and forcing data sets. The satellite-derived relationships indicate strong sensitivity to climate variables (e.g. maximum temperature, number of wet days), vegetation properties (e.g. vegetation type, previous-season plant productivity and leaf area, woody litter), and to socio-economic variables (e.g. human population density). DGVMs broadly reproduce the relationships with climate variables and, for some models, with population density. Interestingly, satellite-derived responses show a strong increase in burned area with an increase in previous-season leaf area index and plant productivity in most fire-prone ecosystems, which was largely underestimated by most DGVMs. Hence, our pattern-oriented model evaluation approach allowed us to diagnose that vegetation effects on fire are a main deficiency regarding fire-enabled dynamic global vegetation models' ability to accurately simulate the role of fire under global environmental change.

Journal ArticleDOI
TL;DR: In this article, the authors thank the Bavarian Forest National Park administration for funding the travel costs of RN and DL in support of this manuscript and acknowledge support from grants from ABL and FJCI-2015-23687.
Abstract: We thank the Bavarian Forest National Park administration for funding the travel costs of RN and DL in support of this manuscript. ABL acknowledges support from grants P12-RNM-2705 and FJCI- 2015–23687.

Journal ArticleDOI
TL;DR: In this paper, a European research network on forest ownership change is developed, based on conceptual work, literature reviews and empirical evidence from 28 European countries, and the authors discuss relevant issues and provide conceptual and practical foundations for future research, forest management approaches, and policy making.

Journal ArticleDOI
05 Jul 2019-Cancers
TL;DR: For the functional capacity and medical care parameters, preoperative combined aerobic, resistance, and inspiratory muscle training was shown to be effective if comprising one to four weeks, performing 1–3 sessions per week, with moderate intensity (50% for endurance capacity).
Abstract: Preoperative physical exercise protocols prior to cancer surgery increased in popularity over recent years; however, the beneficial effect of such protocols is not well established, with conflicting results reported. We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) to assess the effects of different modalities or combinations of preoperative exercise interventions and/or prehabilitation multicomponent training in patients with non-small-cell lung cancer (NSCLC) after surgery on the outcomes related to functional capacity, mental wellness and medical care. We searched in OVID Embase, Pubmed, Cochrane Library, CINAHL, Scopus, and Web of Science. Characteristics of studies and program results and outcome data were extracted. Changes between the intervention and control groups, from baseline to follow-up (standardized mean difference (SMD) or relative risk (RR) with 95% confidence interval (CI) for each intervention was pooled using weighted random-effects models). A total of 676 participants from 10 RCTs were included in the final analysis (aerobic training + inspiratory muscle training, n = 5; aerobic training + strength training + inspiratory muscle training, n = 2; aerobic training + strength training, n = 1; multicomponent training, n = 1; aerobic training alone, n = 1). The results showed intervention-induced improvement in walking endurance (SMD = 0.27; 95% CI, 0.11 to 0.44; I2 = 0.0%), peak exercise capacity (SMD = 0.78; 95% CI, 0.35 to 1.21; I2 = 76.7%), dyspnoea (SMD = -0.30; 95% CI, -0.51 to -0.10; I2 = 0.0%), risk of hospitalization (SMD = -0.58; 95% CI, -0.97 to -0.20; I2 = 70.7%), and postoperative pulmonary complications (relative risk (RR) = 0.50; 95% CI, 0.39 to 0.66; I2 = 0.0%). For the functional capacity and medical care parameters, preoperative combined aerobic, resistance, and inspiratory muscle training was shown to be effective if comprising one to four weeks, performing 1-3 sessions per week, with moderate intensity (50% for endurance capacity). Further studies with larger samples and higher methodological quality are needed to clarify the potential benefits of preoperative exercise training for patients with NSCLC.