Institution
University of Düsseldorf
Education•Düsseldorf, Germany•
About: University of Düsseldorf is a education organization based out in Düsseldorf, Germany. It is known for research contribution in the topics: Population & Diabetes mellitus. The organization has 25225 authors who have published 49155 publications receiving 1946434 citations.
Topics: Population, Diabetes mellitus, Transplantation, Gene, Medicine
Papers published on a yearly basis
Papers
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13 Sep 1995TL;DR: The method uses simple non-linear modifications of Gaussian filters, thus avoiding iteration steps and convergence problems and providing excellent smoothing of fine image details without destroying the coarser structures.
Abstract: This paper presents a new diffusion method for edge preserving smoothing of images. In contrast to other methods it is not based on an anisotropic modification of the heat conductance equation, rather on a modification of the way the solution of the heat conductance equation is obtained by convolving the initial data with a Gaussian kernel. Hence the method uses simple non-linear modifications of Gaussian filters, thus avoiding iteration steps and convergence problems. A chain of three to five filters with suitable parameters provides excellent smoothing of fine image details without destroying the coarser structures. The size and contrast of the eliminated details can be selected. The choice of the parameters is not critical and the edges are not displaced when changing the scale. The filter stages can be implemented efficiently on almost any parallel hardware architecture.
339 citations
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TL;DR: Multivariable analyses revealed a high allelic ratio as a predictive factor for the beneficial effect of allogeneic HSCT; ITD IS in TKD1 remained an unfavorable factor, whereas no prognostic impact of concurrent gene mutations was observed.
339 citations
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TL;DR: Modulation of NO synthesis and action represents a new approach to the treatment of inflammatory and autoimmune conditions.
339 citations
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TL;DR: In this paper, the adsorption/desorption of up to 0.75 g of water vapour per g of the porous MOFs 3D-{M3O(X)(H2O)2[btc]2·n H2O}, MIL-100 (M = Al, Fe; X = OH, F, btc = benzene-1,3,5-tricarboxylate, trimesate), occurs at small relative pressures of p/p0 < 0.4 and a comparatively small hysteres
Abstract: The adsorption/desorption of up to 0.75 g of water vapour per g of the porous MOFs 3D-{M3O(X)(H2O)2[btc]2·nH2O}, MIL-100 (M = Al, Fe; X = OH, F, btc = benzene-1,3,5-tricarboxylate, trimesate), occurs at small relative pressures of p/p0 < 0.4 and a comparatively small hysteresis. Together with very good cycle stability, these properties render both MIL-100(Al and Fe) very suitable candidates for thermally driven heat pumps or adsorption chillers.
339 citations
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University of Pisa1, Dresden University of Technology2, University of Crete3, University of Texas at Austin4, University of Barcelona5, University of Padua6, Cambridge University Hospitals NHS Foundation Trust7, St Thomas' Hospital8, University of Münster9, University of Birmingham10, Johns Hopkins University11, University of Düsseldorf12, Tel Aviv Sourasky Medical Center13, Sheba Medical Center14, Tel Aviv University15, Medical University of Vienna16, Karolinska Institutet17, National Institutes of Health18, University of Pennsylvania19
TL;DR: A ‘core set’ of minimal variables for the assessment and monitoring of patients with SLE in clinical practice was developed that included some of the recommendations and indications for specific organ assessments that were viewed as part of good clinical practice.
Abstract: Objectives: To develop recommendations for monitoring patients with systemic lupus erythematosus (SLE) in clinical practice and observational studies and to develop a standardised core set of variables to monitor SLE. Methods: We followed the European League Against Rheumatism (EULAR) standardised procedures for guideline development. The following techniques were applied: nominal groups, Delphi surveys for prioritisation, small group discussion, systematic literature review and two Delphi rounds to obtain agreement. The panel included rheumatologists, internists, dermatologists, a nephrologist and an expert related to national research agencies. The level of evidence and grading of recommendations were determined according to the Levels of Evidence and Grades of Recommendations of the Oxford Centre for Evidence-Based Medicine. Results: A total of 10 recommendations have been developed, covering the following aspects: patient assessment, cardiovascular risk factors, other risk factors (osteoporosis, cancer), infection risk (screening, vaccination, monitoring), frequency of assessments, laboratory tests, mucocutaneous involvement, kidney monitoring, neuropsychological manifestations and ophthalmology assessment. A ‘core set’ of minimal variables for the assessment and monitoring of patients with SLE in clinical practice was developed that included some of the recommendations. In addition to the recommendations, indications for specifi c organ assessments that were viewed as part of good clinical practice were discussed and included in the fl ow chart. Conclusions: A set of recommendations for monitoring patients with SLE in routine clinical practice has been developed. The use of a standardised core set to monitor patients with SLE should facilitate clinical practice, as well as the quality control of care for patients with SLE, and the collection and comparison of data in observational studies.
338 citations
Authors
Showing all 25575 results
Name | H-index | Papers | Citations |
---|---|---|---|
Karl J. Friston | 217 | 1267 | 217169 |
Roderick T. Bronson | 169 | 679 | 107702 |
Stanley B. Prusiner | 168 | 745 | 97528 |
Ralph A. DeFronzo | 160 | 759 | 132993 |
Monique M.B. Breteler | 159 | 546 | 93762 |
Thomas Meitinger | 155 | 716 | 108491 |
Karl Zilles | 138 | 692 | 72733 |
Ruben C. Gur | 136 | 741 | 61312 |
Alexis Brice | 135 | 870 | 83466 |
Michael Schmitt | 134 | 2007 | 114667 |
Michael Weller | 134 | 1105 | 91874 |
Helmut Sies | 133 | 670 | 78319 |
Peter T. Fox | 131 | 622 | 83369 |
Yuri S. Kivshar | 126 | 1845 | 79415 |
Markus M. Nöthen | 125 | 943 | 83156 |