Institution
University of Medicine and Dentistry of New Jersey
Education•
About: University of Medicine and Dentistry of New Jersey is a based out in . It is known for research contribution in the topics: Population & Pregnancy. The organization has 14634 authors who have published 19610 publications receiving 1041794 citations.
Topics: Population, Pregnancy, Poison control, Gene, Receptor
Papers published on a yearly basis
Papers
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TL;DR: Survival has substantially improved for head and neck cancer patients over the past decade, with the greatest improvement seen in tonsillar and tongue cancers.
Abstract: Background.
Therapy for head and neck cancers has evolved over the past decade, but few detailed analyses of recent developments in survival on the population level have been published.
633 citations
TL;DR: A p53-regulated gene product, TSAP6, was shown to enhance exosome production in cells undergoing a p53 response to stress, indicating that the p53 pathway regulates the production of exosomes into the medium and these vesicles can communicate with adjacent cells and even cells of the immune system.
Abstract: The p53 protein responds to stress signals by regulating the transcription of a variety of genes. Some of these genes encode secreted proteins that may be involved in the communication between adjacent cells. In this study, a proteomics approach was employed to identify proteins secreted by cells in a p53-dependent manner after DNA damage. In addition to the known transcriptional targets of p53, a set of proteins encoded by genes that are not transcriptional targets of p53 were found to increase in the culture medium after p53 activation. These proteins exit the cell via small, secreted vesicles called exosomes and exosome production by cells was found to be regulated by the p53 response. A p53-regulated gene product, TSAP6, was shown to enhance exosome production in cells undergoing a p53 response to stress. Thus, the p53 pathway regulates the production of exosomes into the medium and these vesicles can communicate with adjacent cells and even cells of the immune system.
632 citations
TL;DR: The periconceptional use of folic acid-containing supplements reduces the first occurrence, as well as the recurrence, of neural tube defects, and the risk of poor pregnancy outcome and of decreased birth weight and gestation duration.
624 citations
TL;DR: While iron supplementation may improve pregnancy outcome when the mother is iron deficient it is also possible that prophylactic supplementation may increase risk when theMother does not have iron deficiency or IDA, and iron supplements and increased iron stores have recently been linked to maternal complications.
623 citations
TL;DR: The SOFA score provides potentially valuable prognostic information on in-hospital survival when applied to patients with severe sepsis with evidence of hypoperfusion at the time of emergency department (ED) presentation.
Abstract: Objectives:Organ failure worsens outcome in sepsis. The Sequential Organ Failure Assessment (SOFA) score numerically quantifies the number and severity of failed organs. We examined the utility of the SOFA score for assessing outcome of patients with severe sepsis with evidence of hypoperfusion at t
622 citations
Authors
Showing all 14639 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| John Q. Trojanowski | 226 | 1467 | 213948 |
| Virginia M.-Y. Lee | 194 | 993 | 148820 |
| Danny Reinberg | 145 | 342 | 68201 |
| Michael F. Holick | 145 | 767 | 107937 |
| Tasuku Honjo | 141 | 712 | 88428 |
| Arnold J. Levine | 139 | 485 | 116005 |
| Aaron T. Beck | 139 | 536 | 170816 |
| Charles J. Yeo | 136 | 672 | 76424 |
| Jerry W. Shay | 133 | 639 | 74774 |
| Chung S. Yang | 128 | 560 | 56265 |
| Paul G. Falkowski | 127 | 378 | 64898 |
| Csaba Szabó | 123 | 958 | 61791 |
| William C. Roberts | 122 | 1117 | 55285 |
| Bryan R. Cullen | 121 | 371 | 50901 |
| John R. Perfect | 119 | 573 | 52325 |