Asia–Pacific clinical practice guidelines on the management of hepatocellular carcinoma: a 2017 update
Masao Omata,Ann-Lii Cheng,Norihiro Kokudo,Masatoshi Kudo,Jeong Min Lee,Jidong Jia,Ryosuke Tateishi,Kwang Hyub Han,Yoghesh K. Chawla,Shuichiro Shiina,Wasim Jafri,Diana A. Payawal,Takamasa Ohki,Sadahisa Ogasawara,Pei-Jer Chen,Cosmas Rinaldi Adithya Lesmana,Laurentius A. Lesmana,Rino Alvani Gani,Shuntaro Obi,A. Kadir Dokmeci,Shiv Kumar Sarin +20 more
TLDR
The latest guidelines for the treatment of HCC recommend evidence-based management and are considered suitable for universal use in the Asia–Pacific region, which has a diversity of medical environments.Abstract:
There is great geographical variation in the distribution of hepatocellular carcinoma (HCC), with the majority of all cases worldwide found in the Asia–Pacific region, where HCC is one of the leading public health problems. Since the “Toward Revision of the Asian Pacific Association for the Study of the Liver (APASL) HCC Guidelines” meeting held at the 25th annual conference of the APASL in Tokyo, the newest guidelines for the treatment of HCC published by the APASL has been discussed. This latest guidelines recommend evidence-based management of HCC and are considered suitable for universal use in the Asia–Pacific region, which has a diversity of medical environments.read more
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Review of recent research on hepatitis C therapy for 54th annual meeting of the American association for the study of liver diseases
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Ledipasvir and Sofosbuvir Plus Ribavirin for Treatment of HCV Infection in Patients With Advanced Liver Disease
Michael Charlton,Gregory T. Everson,Steven L. Flamm,Princy Kumar,Charles Landis,Robert S. Brown,Michael W. Fried,Norah A. Terrault,Jacqueline G. O'Leary,Hugo E. Vargas,Alexander Kuo,Eugene R. Schiff,Mark S. Sulkowski,Richard Gilroy,Kymberly D. Watt,Kimberly A Brown,Paul Y. Kwo,Surakit Pungpapong,Kevin M. Korenblat,Andrew J. Muir,Lewis Teperman,Robert J. Fontana,Jill Denning,Sarah Arterburn,Hadas Dvory-Sobol,Theo S. Brandt-Sarif,Phillip S. Pang,John G. McHutchison,K. Rajender Reddy,Nezam H. Afdhal +29 more
TL;DR: The combination of ledipasvir, sofosbuvir, and ribavirin for 12 weeks produced high rates of SVR12 in patients with advanced liver disease, including those with decompensated cirrhosis before and after liver transplantation.
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Epidemiology and surveillance for hepatocellular carcinoma: New trends
TL;DR: The current state of HCC surveillance is reviewed and areas for future research are highlighted, including improved risk stratification of at-risk patients, surveillance tools with higher sensitivity and specificity for early HCC, and interventions to increase surveillance utilisation.
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Chronic Hepatitis B Infection: A Review
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TL;DR: The Global Burden of Diseases, Injuries, and Risk Factors Study 2010 aimed to estimate annual deaths for the world and 21 regions between 1980 and 2010 for 235 causes, with uncertainty intervals (UIs), separately by age and sex, using the Cause of Death Ensemble model.
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