Journal ArticleDOI
Chemistry and application of 4-oxo-4H-1-benzopyran-3-carboxaldehyde
TLDR
The chemistry and application of the title aldehyde and some simple derivatives thereof are reviewed in this paper, where the authors propose a simple derivative of the aldehydes, which they call simple aldeheeds.About:
This article is published in Journal of Heterocyclic Chemistry.The article was published on 2008-11-01. It has received 42 citations till now. The article focuses on the topics: Benzopyran.read more
Citations
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Journal ArticleDOI
Recyclizations of 3-formylchromones with binucleophiles
Andrey S. Plaskon,Andrey S. Plaskon,Oleksandr O. Grygorenko,Oleksandr O. Grygorenko,Sergey V. Ryabukhin +4 more
Journal ArticleDOI
4-Chloro-3-(trifluoroacetyl)- and 4-chloro-3-(methoxalyl)coumarins as novel and efficient building blocks for the regioselective synthesis of 3,4-fused coumarins
Viktor O. Iaroshenko,Viktor O. Iaroshenko,Friedrich Erben,Satenik Mkrtchyan,Satenik Mkrtchyan,Ani Hakobyan,Ani Hakobyan,Marcelo Vilches-Herrera,Sergii Dudkin,Alina Bunescu,Alexander Villinger,Vyacheslav Ya. Sosnovskikh,Peter Langer +12 more
TL;DR: In this article, the starting materials were prepared by the reaction of 4-hydroxycoumarin with trifluoroacetic anhydride and methyl 2-chloro-2-oxoacetate in the presence of trimethylsilylchloride.
Journal ArticleDOI
Three-component reactions of isocyanoacetates, amines and 3-formylchromones initiated by an unexpected aza-Michael addition.
TL;DR: A new mode of three-component reactions between isocyanoacetates, amines and 3-formylchromones is presented, which enables an efficient synthesis of polysubstituted pyrroles.
Journal ArticleDOI
3-Methoxalylchromone—a novel versatile reagent for the regioselective purine isostere synthesis
Satenik Mkrtchyan,Viktor O. Iaroshenko,Viktor O. Iaroshenko,Sergii Dudkin,Ashot Gevorgyan,Marcelo Vilches-Herrera,Gagik Ghazaryan,Dmitriy M. Volochnyuk,Dmitriy M. Volochnyuk,Dmytro Ostrovskyi,Zeeshan Ahmed,Alexander Villinger,Vyacheslav Ya. Sosnovskikh,Peter Langer +13 more
TL;DR: The first synthesis of 3-methoxalylchromone was described, where the reaction of the latter with electron-rich aminoheterocycles afforded a set of heteroannelated pyridines bearing a CO(2)Me substituent located at the α-position of the pyridine core.
Journal ArticleDOI
Synthesis of Chromone-Related Pyrazole Compounds.
TL;DR: This review will cover the literature on the chromone and pyrazole dual chemistry and their outcomes in the 21st century with a focus on the synthesis of chromone-pyrazole dyads.
References
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Journal ArticleDOI
A versatile route to 2-alkyl-/aryl-amino-3-formyl- and hetero-annelated-chromones, through a facile nucleophilic substitution at C2 in 2-(N-methylanilino)-3-formylchromones
TL;DR: The N-methylanilino group in 2-(Nmethylonilino)-3-formylchromones, obtained in high yield by rearrangement of C(4-oxo-4H[1]-benzopyran-3-yl)-N-phenylnitrones to 2-anilino-3 -formyl-chromones followed by N-methylation, undergoes facile nucleophilic substitution by a variety of nitrogen nucleophiles, thereby paving the way for synthesis of novel 2-substituted
Journal ArticleDOI
Annulation Reactions of Allene-Derived 1,3-Dipole with 3-Substituted-Chromones: Unusual Recognition of 4π-Component in 3-(N-Aryliminomethyl)chromones through [4 + 3] Annulation
TL;DR: In this article, an all-carbon dipole derived by the interaction of triphenylphosphine with allenic ester is able to locate the polarized 2π-component in 3-formylchromones through a regioselective [2 + 3] addition to the C2−C3 π-bond, which is followed by deformylation leading to novel 3a,9a-dihydro-1-ethoxycarbonyl-1 -cyclopenteno[5,4-b]benzopyran-4
Journal ArticleDOI
Chemistry of 4-Oxo-4H-[1]benzopyran-3-carboxaldehyde
TL;DR: The authors present an examen approfondi de la synthese, des proprietes et des reactions de l'oxo-4 chromenecarbaldehyde-3 and l'utilisation de ses condensats for the preparation of divers systemes chimiques.
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Efficient acetalisation of aldehydes catalyzed by titanium tetrachloride in a basic medium
TL;DR: In this paper, the authors used catalytic amount of Ti(IV) chloride in MeOH in the presence of NH3 or Et3N to achieve the acetalization of aliphatic and aromatic aldehydes.
Journal ArticleDOI
Progress in 5H[1]benzopyrano[4,3-d]pyrimidin-5-amine series: 2-methoxy derivatives effective as antiplatelet agents with analgesic activity.
Olga Bruno,Chiara Brullo,Silvia Schenone,Angelo Ranise,Francesco Bondavalli,Elisabetta Barocelli,Massimiliano Tognolini,Francesca Magnanini,Vigilio Ballabeni +8 more
TL;DR: Title compounds showed antiplatelet activity in aggregation AA or collagen-induced, and a good analgesic activity without any gastric toxicity.