Journal ArticleDOI
Chemistry and application of 4-oxo-4H-1-benzopyran-3-carboxaldehyde
TLDR
The chemistry and application of the title aldehyde and some simple derivatives thereof are reviewed in this paper, where the authors propose a simple derivative of the aldehydes, which they call simple aldeheeds.About:
This article is published in Journal of Heterocyclic Chemistry.The article was published on 2008-11-01. It has received 42 citations till now. The article focuses on the topics: Benzopyran.read more
Citations
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Journal ArticleDOI
Recyclizations of 3-formylchromones with binucleophiles
Andrey S. Plaskon,Andrey S. Plaskon,Oleksandr O. Grygorenko,Oleksandr O. Grygorenko,Sergey V. Ryabukhin +4 more
Journal ArticleDOI
4-Chloro-3-(trifluoroacetyl)- and 4-chloro-3-(methoxalyl)coumarins as novel and efficient building blocks for the regioselective synthesis of 3,4-fused coumarins
Viktor O. Iaroshenko,Viktor O. Iaroshenko,Friedrich Erben,Satenik Mkrtchyan,Satenik Mkrtchyan,Ani Hakobyan,Ani Hakobyan,Marcelo Vilches-Herrera,Sergii Dudkin,Alina Bunescu,Alexander Villinger,Vyacheslav Ya. Sosnovskikh,Peter Langer +12 more
TL;DR: In this article, the starting materials were prepared by the reaction of 4-hydroxycoumarin with trifluoroacetic anhydride and methyl 2-chloro-2-oxoacetate in the presence of trimethylsilylchloride.
Journal ArticleDOI
Three-component reactions of isocyanoacetates, amines and 3-formylchromones initiated by an unexpected aza-Michael addition.
TL;DR: A new mode of three-component reactions between isocyanoacetates, amines and 3-formylchromones is presented, which enables an efficient synthesis of polysubstituted pyrroles.
Journal ArticleDOI
3-Methoxalylchromone—a novel versatile reagent for the regioselective purine isostere synthesis
Satenik Mkrtchyan,Viktor O. Iaroshenko,Viktor O. Iaroshenko,Sergii Dudkin,Ashot Gevorgyan,Marcelo Vilches-Herrera,Gagik Ghazaryan,Dmitriy M. Volochnyuk,Dmitriy M. Volochnyuk,Dmytro Ostrovskyi,Zeeshan Ahmed,Alexander Villinger,Vyacheslav Ya. Sosnovskikh,Peter Langer +13 more
TL;DR: The first synthesis of 3-methoxalylchromone was described, where the reaction of the latter with electron-rich aminoheterocycles afforded a set of heteroannelated pyridines bearing a CO(2)Me substituent located at the α-position of the pyridine core.
Journal ArticleDOI
Synthesis of Chromone-Related Pyrazole Compounds.
TL;DR: This review will cover the literature on the chromone and pyrazole dual chemistry and their outcomes in the 21st century with a focus on the synthesis of chromone-pyrazole dyads.
References
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Journal ArticleDOI
Synthesis and pharmacological evaluation of 2,5-cycloamino-5H-[1]benzopyrano[4,3-d]pyrimidines endowed with in vitro antiplatelet activity.
Olga Bruno,Chiara Brullo,Angelo Ranise,Silvia Schenone,Francesco Bondavalli,Elisabetta Barocelli,Vigilio Ballabeni,Milena Chiavarini,Massimiliano Tognolini,Mariannina Impicciatore +9 more
TL;DR: Title compounds were ineffective in vivo and in vitro; however, the pyrrolidino derivatives 3a and 3c exhibited an antiplatelet activity against all the aggregants differing from that of acetylsalicylic acid (ASA) while the 5-morpholino derivatives3g-i showed the most potent ASA-like antiplatelets activity.
Journal ArticleDOI
New polycyclic pyrimidine derivatives with antiplatelet in vitro activity: synthesis and pharmacological screening
Olga Bruno,Silvia Schenone,Angelo Ranise,Francesco Bondavalli,Elisabetta Barocelli,Vigilio Ballabeni,Milena Chiavarini,Simona Bertoni,Massimiliano Tognolini,Mariannina Impicciatore +9 more
TL;DR: Findings indicate that the 5-pyrrolidino-2-methylthiobenzopyrano[4,3-d]pyrimidine 4d fulfils the chemical requirements to exhibit antiplatelet activity associated with gastroprotective effect.
Journal ArticleDOI
Synthesis, structure, infrared and fluorescence spectra of new rare earth complexes with 6-hydroxy chromone-3-carbaldehyde benzoyl hydrazone
TL;DR: Observations show that the ligand favor energy transfers to the emitting energy level of Eu3+.
Journal ArticleDOI
Heterocycles directly linked to 3-position of 1-benzopyran-4-ones
Journal ArticleDOI
Synthesis of 6-(2-hydroxybenzoyl)pyrazolo[1,5-a]pyrimidines by reaction of 5-amino-1H-pyrazoles and 3-formylchromone
Jairo Quiroga,Diana Mejía,Braulio Insuasty,Rodrigo Abonia,Manuel Nogueras,Adolfo Sánchez,Justo Cobo,John N. Low +7 more
TL;DR: In this paper, the reaction of 3-formylchromone (1) with 5-amino-1H-pyrazoles (2) in ethanol, afforded 6-(2-hydroxy-benzoyl)pyrazolo[1,5-a]pyrimidines (3a-g) in good yields.