Cytokine Storm.
David C. Fajgenbaum,Carl H. June +1 more
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From the Department of Medicine, Division of Translational Medicine and Human Genetics, Center for Cytokine Storm Treatment and Laboratory, and the Center for Cellular Immunotherapies and the Parker Institute for Cancer Immunotherapy, University of Pennsylvania, Philadelphia.Abstract:
From the Department of Medicine, Division of Translational Medicine and Human Genetics, Center for Cytokine Storm Treatment and Laboratory (D.C.F.), and the Center for Cellular Immunotherapies and the Parker Institute for Cancer Immunotherapy (C.H.J.), Perelman School of Medicine, University of Pennsylvania, Philadelphia. Address reprint requests to Dr. Fajgenbaum at davidfa@ pennmedicine . upenn . edu or to Dr. June at cjune@ upenn . edu.read more
Citations
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The Role of an Anti-Inflammatory Diet in Conjunction to COVID-19
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TL;DR: This review aimed to directly address ncRNA role in SARS-CoV-2-immune system crosstalk upon COVID-19 infection, particularly focusing on inflammatory pathways and cytokine storm syndromes.
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Endothelium-protective, histone-neutralizing properties of the polyanionic agent defibrotide.
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TL;DR: In this article, the FDA-approved polyanionic agent defibrotide (a pleiotropic mixture of oligonucleotides) directly engages histones and thereby blocks their pathological effects on endothelium.
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Bleeding Complications in Patients With Perioperative COVID-19 Infection Undergoing Cardiac Surgery: A Single-Center Matched Case-Control Study
TL;DR: In this article , the authors investigated a possible significant correlation between perioperative COVID-19 infection and hemorrhagic complications compared to non-COVID19 patients and found that COVID infection is confirmed to markedly increase the postoperative risk.
References
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TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties.
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Gout-associated uric acid crystals activate the NALP3 inflammasome
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