Journal ArticleDOI
Encoded evidence: DNA in forensic analysis
Mark A. Jobling,Peter Gill +1 more
TLDR
For example, forensic DNA analysis is key to the conviction or exoneration of suspects and the identification of victims of crimes, accidents and disasters, driving the development of innovative methods in molecular genetics, statistics and the use of massive intelligence databases as mentioned in this paper.Abstract:
Sherlock Holmes said "it has long been an axiom of mine that the little things are infinitely the most important", but never imagined that such a little thing, the DNA molecule, could become perhaps the most powerful single tool in the multifaceted fight against crime. Twenty years after the development of DNA fingerprinting, forensic DNA analysis is key to the conviction or exoneration of suspects and the identification of victims of crimes, accidents and disasters, driving the development of innovative methods in molecular genetics, statistics and the use of massive intelligence databases.read more
Citations
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Journal ArticleDOI
DNA evidence: Current perspective and future challenges in India
TL;DR: A comprehensive review on the status of DNA testing in India is provided and the consequences of the admissibility of DNA as 'evidence' in the judicial dominion are elucidated.
Journal ArticleDOI
Tested at Last How DNA Evidence in Untested Rape Kits Can Identify Offenders and Serial Sexual Assaults
TL;DR: A sample of 900 previously unsubmitted SAKs from Detroit, Michigan were tested and the DNA forensic testing outcomes associated with those kits were documented, showing how many yielded DNA profiles eligible for upload into CODIS, the federal DNA criminal database, and how many resulted in a DNA match.
Journal ArticleDOI
Expanding beyond the current core STR loci: An exploration of 73 STR markers with increased diversity for enhanced DNA mixture deconvolution.
Nicole M.M. Novroski,Frank R. Wendt,August E. Woerner,Magdalena M. Bus,Michael D. Coble,Bruce Budowle +5 more
TL;DR: Exploratory data of a multiplex comprised of 73 highly polymorphic STRs that were selected because of their high diversity due to sequence variation are presented, illustrating the increased value of utilizing sequenced-based alleles of additional STR loci.
Journal ArticleDOI
Forensic DNA Profiling: Autosomal Short Tandem Repeat as a Prominent Marker in Crime Investigation.
Udogadi Nwawuba Stanley,Abdullahi Mohammed Khadija,Adams Tajudeen Bukola,Imose Omusi Precious,Esewi Ayevbuomwan Davidson +4 more
TL;DR: It has become very necessary for developing countries like Nigeria to develop a national DNA database and make policies and legislatures that will further expand and enable the practice of forensic genetics, particularly DNA profiling.
Journal ArticleDOI
Analyzing degraded DNA and challenging samples using the ForenSeq™ DNA Signature Prep kit.
TL;DR: The ForenSeq™ DNA Signature Prep kit was tested in repeated experimental runs on series of degraded DNA samples, ranging from mild to severe degradation, as well as 24 mock case-type samples, derived from bones, blood cards, and teeth, to demonstrate that it can be successfully used on degradedDNA samples.
References
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Journal ArticleDOI
Hypervariable 'minisatellite' regions in human DNA.
TL;DR: A probe based on a tandem-repeat of the core sequence can detect many highly variable loci simultaneously and can provide an individual-specific DNA ‘fingerprint’ of general use in human genetic analysis.
Book ChapterDOI
The Apportionment of Human Diversity
TL;DR: Lewontin this article pointed out that even in the present era of Darwinism there is considerable diversity of opinion about the amount or importance of intragroup variation as opposed to the variation between races and species.
Journal ArticleDOI
Individual-specific 'fingerprints' of human DNA.
TL;DR: It is shown that other variant (core)n probes can detect additional sets of hypervariable minisatellites to produce somatically stable DNA ‘fingerprints’ which are completely specific to an individual (or to his or her identical twin) and can be applied directly to problems of human identification, including parenthood testing.